A5059966861- Multicomponent Synthesis of Heterocycles
- Quinazolinone synthesis and applications
- Synthesis and biological activity
- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Synthesis and Biological Evaluation
- Phenothiazines and Benzothiazines Synthesis and Activities
- Crystallization and Solubility Studies
- Angiogenesis and VEGF in Cancer
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Reactions
- X-ray Diffraction in Crystallography
- Polyoxometalates: Synthesis and Applications
- Oxidative Organic Chemistry Reactions
- Advanced Synthetic Organic Chemistry
- Synthesis and Reactions of Organic Compounds
- Metal-Catalyzed Oxygenation Mechanisms
- Cytokine Signaling Pathways and Interactions
- Click Chemistry and Applications
- Asymmetric Synthesis and Catalysis
- Cancer Mechanisms and Therapy
- Metal complexes synthesis and properties
- Synthesis and Catalytic Reactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Synthesis of Organic Compounds
North China University of Science and Technology
2020-2025
Beijing University of Technology
2013-2024
China Resources (China)
2024
Bioengineering Center
2018
A facile and efficient visible-light mediated method was reported, which would convert a series of sulfides into sulfoxides without using any photocatalysts. Moreover, the reaction mechanism studied both experimentally theoretically.
Abstract An ultrasound‐assisted facile condensation reaction was developed to synthesize the benzothiazoles. The conditions are mild and do not require toxic metals or ligands, making it an efficient synthesis strategy. Starting from commercially available aldehydes 2‐aminothiophenols, this method found have wide functional group compatibility, resulting in a series of benzothiazole derivates moderate excellent yields. Moreover, all derivatives been characterized by 1 H NMR, 13 C HRMS.
A green, simple and efficient method is developed for the synthesis of quinazolin-4(3H)-ones via visible light-induced condensation cyclization 2-aminobenzamides aldehydes under light irradiation. The reaction proceeds using fluorescein as a photocatalyst in presence TBHP without need metal catalyst. In addition, this tolerates broad scope substrates could afford variety desirable products good to excellent yields. Thus, present synthetic provides straightforward strategy quinazolin-4(3H)-ones.
A series of 2-amino-3-cyano-4-aryl-4H-pyrans (1) were synthesised by reacting malononitrile, ethyl acetoacetate, and aromatic aldehydes under ultrasound irradiation. The photochemical properties, including the photostability photoreaction 1, investigated in conventional solvents. results indicated that compounds 1 unstable underwent a to 1,3-butadienes irradiation with UV light. mechanism for is proposed using electron spin resonance spectroscopic techniques. 1,3-butadiene structures...
Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a crucial role in tumor angiogenesis, and inhibition of the VEGFR-2 signaling pathway has emerged as an attractive target for cancer therapy.
A concise and efficient photocatalytic C-C coupling of 1-benzyl-3-cyano-1,4-dihydropyridine for synthesis 1,1'-dibenzyl-3,3'-dicyano-1,1',4,4'-tetrahydro-4,4'-bipyridine is described. The reporter system provides a novel technique that facilitates derivatives without addition transition metals oxidants or other additives. plausible synthetic pathway proposed, the product was characterized via nuclear magnetic resonance spectroscopy (1H 13C NMR), high-resolution electrospray ionization mass...
A green, simple and efficient method is developed for the synthesis of quinazolin-4(3H)-ones via visible light-induced condensation cyclization 2-aminobenzamides aldehydes under light irradiation. The reaction proceeds using fluorescein as photocatalyst in presence TBHP without need metal catalyst. In addition, this tolerates a broad scope substrates could afford variety desirable products good to excellent yields. Thus, present synthetic provides straightforward strategy quinazolin-4(3H)-ones.
A metal-free and solvent-free method for the synthesis of quinazolin-4(3H)-ones is proposed by condensation cyclization 2-aminobenzamides aldehydes using 1-butyl-3-methylimida-zolium tetrafluoride ([Bmim]BF4) as ionic liquid catalyst. In this reaction, [Bmim]BF4 acts both a catalyst solvent without need additional catalysts solvents. This exhibits favorable functional group tolerance in substrates affords series desired products moderate to excellent yields. addition, it noteworthy that...
Abstract C 26 H 22 BrN 3 O , monoclinic, P 2 1 / c (no. 14), a = 17.7467(15) Å, b 10.7974(8) 11.9136(8) β 96.084°, V 2270.0(3) Å Z 4, R gt ( F ) 0.0375, wR ref 0.1205, T 293 K.
Ultrasound irradiation has emerged as a novel and powerful operational approach for the fast synthesis of quinazolinones. The was successfully applied under ambient temperature pressure conditions without need metal catalyst.
The asymmetric epoxidation of olefins is one the most studied reactions due to high synthetic value resulting enantiopure epoxides. authors report development a novel family chiral Mn(II) complexes N4-ligands for enones and nonfunctionalized olefins, with H2O2 in presence acetic acid. With 1 mol% catalyst loading, enantioselective proceeds good yields up 89% ee.
Abstract C 26 H 19 Br 2 ClN , triclinic, P <m:math xmlns:m="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <m:mrow> <m:mover accent="true"> <m:mn>1</m:mn> <m:mo>‾</m:mo> </m:mover> </m:mrow> </m:math> $&#x203e;{1}$ (no. 2), a = 9.4830(12) Å, b 10.2313(12) c 13.5948(18) α 111.234(2)°, β 98.025(2)°, γ 101.707(2)°, V 1170.6(3) Å 3 Z 2, R gt ( F ) 0.0444, wR ref 0.1273, T 296 K.