- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Cardiac, Anesthesia and Surgical Outcomes
- Knee injuries and reconstruction techniques
- Cardiac and Coronary Surgery Techniques
- Renal Transplantation Outcomes and Treatments
- Olfactory and Sensory Function Studies
- Sepsis Diagnosis and Treatment
- Total Knee Arthroplasty Outcomes
- Cardiac Ischemia and Reperfusion
- Pain Mechanisms and Treatments
- Cancer Risks and Factors
- Breast Cancer Treatment Studies
- Ovarian function and disorders
- Biochemical Analysis and Sensing Techniques
- Transplantation: Methods and Outcomes
- Metabolism, Diabetes, and Cancer
- Blood transfusion and management
- Growth Hormone and Insulin-like Growth Factors
- Advanced Chemical Sensor Technologies
- Hidradenitis Suppurativa and Treatments
- Tendon Structure and Treatment
- Kruppel-like factors research
- Colorectal Cancer Screening and Detection
- Clinical Reasoning and Diagnostic Skills
Technical University of Munich
2006-2016
University of Salzburg
2016
Klinikum Ingolstadt
2016
Humboldt-Universität zu Berlin
2016
Charité - Universitätsmedizin Berlin
2016
Committee on Publication Ethics
2016
Klinikum rechts der Isar
2008-2009
Universitäts Frauenklinik
2009
Lungenheilkunde München-Pasing
2009
TU Dresden
2009
Purpose Smell and taste changes during chemotherapy are significant complaints of cancer patients. Loss olfactory/gustatory function can lead to malnutrition, weight loss, possibly a prolonged morbidity chemotherapy-induced adverse effects, decreased quality life, poor compliance, even therapy response. This prospective study comprehensively investigated, our knowledge for the first time, smell in cohort 87 patients undergoing breast or gynecologic malignancies. Patients Methods Olfactory...
Autologous osteochondral transplantation is accepted as one of the major treatment options for cartilage defects talus. One disadvantage this technique need to harvest a donor graft from normal knee. The potentially detrimental effect on knee function remains unclear.Two hundred patients who had an autologous obtained asymptomatic defect talus were evaluated. Of 200 patients, 112 followed minimum two years (mean duration follow-up, fifty-five months). WOMAC (Western Ontario and McMaster...
A recent study presented first evidence that a single nucleotide polymorphism (SNP) at codon 388 of fibroblast growth factor receptor 4 (FGFR4) gene, causing transmembrane domain missense mutation (Gly388Arg), is associated with disease outcome in node-positive breast cancer. This article addresses the clinical relevance this SNP, FGFR4 genotype, phenotype, and HER2 regarding patient influence adjuvant systemic therapy substantial primary cancer collective (n = 372; median follow-up, 94.5...
It has long been suspected that a family history of pilonidal sinus disease may predispose to higher incidence. The influence on recurrence rate not investigated. purpose this study was evaluate the in patients with both personal and disease.A standardized telephone interview used retrospectively 578 who underwent primary surgery between 1980 1996. Differences concerning long-term positive or negative were analyzed using Kaplan-Meier statistics.Sixty-eight (12%) had first-degree relatives,...
Increase in muscle force, endurance, and flexibility is desired elite athletes to improve performance avoid injuries, but it often hindered by the occurrence of myofascial trigger points. Dry needling (DN) has been shown effective eliminating points.This randomized controlled study 30 youth soccer players a professional Bundesliga Club investigated effects four weekly sessions DN plus water pressure massage on thigh force range motion hip flexion. A group receiving placebo laser with no...
Expected values for estradiol (E2), luteinizing hormone (LH), and progesterone determined in serum allow accurate assessment of menstrual cycle phase. Automated immunoassays demonstrate variable degrees bias, emphasizing the need to establish method-specific reference values. We therefore established intervals Elecsys® LH assay new generation Elecsys Estradiol III Progesterone assays (cobas e 801 analyzer) 85 apparently healthy women aged 22–37 (US)/18–37 (EU) years over one natural cycle....
In this retrospective analysis we tested the hypothesis that aprotinin doses of more than 6 x 10(6) kallikrein inhibiting units (KIU) per patient may be effective in reducing bleeding compared with high-dose regimen 5-6 KIU aprotinin. The administered for 8281 adult cardiac surgical patients were correlated to body weight and time operation calculated kg minute operation. Linear logistic regression models designed detect potential associations between dose postoperative bleeding,...
In order to improve operating room efficiency, it is desirable predict the duration of scheduled surgeries as precisely possible. The reliability existing predicting models less than satisfactory. This study presents an algorithm estimate time for laparoscopic cholecystectomy, based on historical data 312 patients, taking into account clinical parameters, diagnostic imaging, and surgeon′s experience. algorithm′s accuracy was evaluated in a group 45 patients by prospectively their times. It...
Summary Dysfunction of the graft after liver transplantation caused by ischaemia‐/reperfusion (I/R) injury is a serious clinical problem. The aim this study was to evaluate influence different kinds reperfusion on I/R in rat model. Arterialized orthoptic treatment performed male LEWIS‐(RT 1 )‐rats. Three groups ( n = 7) were formed. Group I: antegrade with 6‐min delayed via hepatic artery. II: Antegrade reperfusion, simultaneously, portal vein and III: Retrograde vena cava. Serum parameters...
Mu-opioidergic agonists are believed to induce euphoria, whereas kappa-agonists thought lead dysphoria. Our study investigated mood effects of remifentanil, a mu-receptor opioid agonist, in healthy male volunteers. Moreover, we examined interactions between and pain. Three conditions were 21 volunteers: saline, 0.05 0.15 microg kg(-1) min(- 1) remifentanil. Each condition was during non-painful heat painful stimulation. Mood measured with the von Zerssen's scale (Bf-S score) pain intensity...
The insulin-like growth factor 1 (IGF1) and its binding protein IGFBP3 (insulin-like 3) play a pivotal role during the development of tissues. purpose this study was to evaluate influence anthracycline- taxane-containing adjuvant chemotherapy in breast cancer patients on circulating plasma levels IGF1 main protein, IGFBP3. This investigation part prospective randomized phase III which were treated with either conventional or dose-intensified chemotherapy. factors quantified 151 commercially...
The insulin-like growth factor 1 (IGF1) and its binding protein IGFBP3 (insulin-like 3) play a pivotal role during the development of tissues. purpose this study was to evaluate influence anthracycline- taxane-containing adjuvant chemotherapy in breast cancer patients on circulating plasma levels IGF1 main protein, IGFBP3. This investigation part prospective randomized phase III which were treated with either conventional or dose-intensified chemotherapy. factors quantified 151 commercially...
Abstract Background: To provide a score to predict the risk of early mortality after single craniocerebral gunshot wound (GSW) based on three clinical parameters. Methods: All patients admitted Baragwanath Hospital, Johannesburg, South Africa, between October 2000 and May 2005 for an isolated GSW were retrospectively evaluated documentation (i) blood pressure (BP) admission; (ii) inspection bullet entry exit site; (iii) initial consciousness ( n = 214). Results: Conscious victims had 8.3%,...