Andrés Rabinovich

ORCID: 0000-0002-9291-9078
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About
Contact & Profiles
Research Areas
  • Trypanosoma species research and implications
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • RNA and protein synthesis mechanisms
  • Coenzyme Q10 studies and effects
  • Research on Leishmaniasis Studies
  • Light effects on plants
  • Photosynthetic Processes and Mechanisms
  • Digital Games and Media
  • Plant Molecular Biology Research
  • Cardiovascular Issues in Pregnancy
  • Synthesis and Biological Evaluation
  • Sports, Gender, and Society
  • Cancer-related gene regulation

Hospital General de Niños Ricardo Gutierrez
2024-2025

Children's Hospital
2024-2025

Consejo Nacional de Investigaciones Científicas y Técnicas
2021-2024

Fundación Instituto Leloir
2021-2024

Genome-wide analysis of alternative splicing has been a very active field research since the early days next generation sequencing technologies. Since then, ever-growing data availability and development increasingly sophisticated methods have uncovered complexity general repertoire. A large number methodologies exist, each them presenting its own strengths weaknesses. For instance, exclusively relying on junction information do not take advantage majority reads produced in an RNA-seq assay,...

10.1093/bioinformatics/btab141 article EN Bioinformatics 2021-02-27

In recent years, attention has been devoted to proteins forming immiscible liquid phases within the intracellular medium, commonly referred as membraneless organelles (MLO). These enable spatiotemporal associations of cellular components that exchange dynamically with milieu. The dysregulation these liquid–liquid phase separation processes (LLPS) may cause various diseases including neurodegenerative pathologies and cancer, among others. Until very recently, databases containing information...

10.1016/j.csbj.2021.06.042 article EN cc-by-nc-nd Computational and Structural Biotechnology Journal 2021-01-01

Background In regions with controlled vector transmission of T . cruzi , congenital is the most frequent route infection. Treatment benznidazole (BZ) or nifurtimox (NF) for 60 days in girls and women childbearing age showed to be effective preventing mother child this disease. Reports on short-course treatment (≤30 days) are scarce. Methods Retrospective cohort study. Offspring Chagas disease who received BZ NF, attended between 2003 2022, were evaluated. Parasitemia (microhaematocrit and/or...

10.1371/journal.pntd.0011895 article EN cc-by PLoS neglected tropical diseases 2024-01-22

Summary When exposed to shade from neighbours, competitive plants modify their growth patterns improve access light. In dense plant stands, ranging forests humid grasslands and crops, is interrupted by sunflecks penetrating the canopy. Relatively infrequent, minute-scale interruptions can significantly contribute daily light input. However, given short duration time gap between these low frequency (LFS), whether sense them was unknown. Here we show that phytochrome B (phyB), cryptochrome 1...

10.1101/2024.02.21.581400 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-22

Chagas disease (ChD) affects approximately 7 million people in Latin America, with benznidazole being the most commonly used treatment.

10.1111/bcp.16214 article EN cc-by British Journal of Clinical Pharmacology 2024-08-29

Abstract Genome-wide analysis of alternative splicing has been a very active field research since the early days NGS (Next generation sequencing) technologies. Since then, ever-growing data availability and development increasingly sophisticated methods have uncovered complexity general repertoire. However, independently considered quantification methodology, often changes in variant concentration profiles can be hard to disentangle. In order tackle this problem we present ASpli2,...

10.1101/2020.06.21.162891 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-06-22
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