A5055342361- Pediatric Pain Management Techniques
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Pain Management and Opioid Use
- Pharmaceutical studies and practices
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Hemoglobinopathies and Related Disorders
- Endometriosis Research and Treatment
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Family and Patient Care in Intensive Care Units
- Menstrual Health and Disorders
- Neonatal Health and Biochemistry
- Neurological Complications and Syndromes
- Pregnancy-related medical research
- Nausea and vomiting management
- Amoebic Infections and Treatments
- Pain Management and Treatment
- Opioid Use Disorder Treatment
- Pharmacogenetics and Drug Metabolism
- Hernia repair and management
- Intestinal and Peritoneal Adhesions
- Heme Oxygenase-1 and Carbon Monoxide
Harvard University
2011-2024
Boston Children's Hospital
2012-2024
Pain and Rehabilitation Medicine
2022
Creative Commons
2018
Izaak Walton Killam Health Centre
2005
The current study was conducted to assess the safety and tolerability of a transdermal fentanyl delivery system for relief chronic pain in pediatric population, also validate titration recommendations conversion from oral opioid therapy.This 15-day (with 3-month extension), single-arm, open-label trial at 66 sites 10 countries. A total 199 patients (ages 2-16 years) with both malignant nonmalignant conditions who were receiving or parenteral opioids moderate severe enrolled. Transdermal...
OBJECTIVES: Identifying the source of pain for children with medical complexity (MC) is challenging. The purpose this study was initial validation a tool to guide evaluation identifying in MC by using differential diagnoses. entitled Guidelines Ruling Out and Assessing Source Pain (GRASP). METHODS: A mixed-methods approach that included expert review, focus groups, Web-based surveys, trial GRASP used determine validity as well perceived clinical utility. RESULTS: Focus groups were held 26...
Summary Epidural abscess following epidural analgesia is an unusual event especially in pediatric patients. Two patients presented with fever and local signs of infection without neurological deficit on day 4 after the initiation analgesia. Neuro‐imaging studies revealed abscess. Both were treated successfully intravenous antibiotics. One patients’ initial MRI was normal. However, symptoms persisted a followed‐up scan The other patient worsening indurations over insertion site positive blood...
Some remedies have long outlived their usefulness and thankfully been relegated to historical archives, supplanted by safer, more effective drugs. We no longer prescribe mercury loop diuretics or antisyphilitic arsenicals. Yet, the use of codeine-containing products persists for cough relief analgesia in children. As Kaiser et al1 report study “National Patterns Codeine Prescriptions Children Emergency Department” this month’s issue, prescriptions barely edged down frequency between 2001...
Typical sickle cell disease (SCD) vaso-occlusive pain episode (VOE) management includes opioids, which are often inadequate and can be associated with significant side effects. Ketamine, a dissociative anesthetic, is potentially effective adjunct to VOE management.This study aimed characterize ketamine use for in pediatric SCD.This retrospective case series summarizes single-center experience regarding the of inpatient 156 admissions from 2014 2020.Continuous low-dose infusion was most...
To develop and implement clinical practice guidelines for safely weaning dexmedetomidine infusions in non-ICU areas.Development, implementation, analysis of effectiveness guidelines.Quaternary care academic free-standing pediatric hospital.Children, otherwise medically ready transfer to areas, who were undergoing a planned wean infusion.Subject matter experts developed evidence-based patients whose critical phase illness had resolved.Searches identified no prospective studies weaning. We two...
Opioids are indicated for moderate-to-severe pain caused by trauma, ischemia, surgery, cancer and sickle cell disease, vaso-occlusive episodes (SCD-VOC). There is only limited evidence regarding the appropriate number of doses to prescribe specific indications. Therefore, we developed implemented an opioid prescribing algorithm with dosing guidelines procedures conditions. We aimed reach sustain 90% compliance within 1 year implementation.We conducted this quality improvement effort at a...
Ketorolac, a nonsteroidal anti-inflammatory drug, is used in combination with opioids to manage vaso-occlusive episodes (VOEs). The relationship between ketorolac use and kidney injury pediatric patients sickle cell disease (SCD) remains incompletely understood. We hypothesize that associated acute (AKI) SCD presenting pain. All nonsurgical hospitalizations for VOEs treated January 2014 December 2022 were included. optimal matching methodology identify control admissions (2:1 ratio)...
To develop and conduct preliminary testing of the Withdrawal Assessment Tool-Alpha 2 Agonist (WAT-A2A) to monitor dexmedetomidine clonidine withdrawal symptoms in acutely ill children. Three-phase instrument development study. Phase 1: retrospective chart review exhibited by children with documented withdrawal; phase 2: WAT-A2A construction based on 1 data; 3: prospective weaning from alpha agonists (A2As). Academic free-standing children's hospital. Acutely at least 5 days dexmedetomidine....
The IASP Satellite Symposia on Pediatric Pain Management: State of the Art and Science will be held from September 10 to 11, 2018 in Boston, MA, just prior official start date World Congress Pain. conference include internationally known speakers focus several prominent themes including pediatric chronic pain rehabilitation, children with developmental disabilities, opioid use misuse, fear related procedural children, as a consequence critical illness. sessions integrate basic, translational...