Karen Boretsky

ORCID: 0000-0003-2799-9902
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About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Pediatric Pain Management Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Airway Management and Intubation Techniques
  • Nausea and vomiting management
  • Ultrasound in Clinical Applications
  • Anesthesia and Neurotoxicity Research
  • Hemodynamic Monitoring and Therapy
  • Anesthesia and Sedative Agents
  • Shoulder Injury and Treatment
  • Intraocular Surgery and Lenses
  • Gastroesophageal reflux and treatments
  • Spine and Intervertebral Disc Pathology
  • Dental Anxiety and Anesthesia Techniques
  • Hip disorders and treatments
  • Muscle and Compartmental Disorders
  • Nicotinic Acetylcholine Receptors Study
  • Pain Management and Opioid Use
  • Orthopedic Surgery and Rehabilitation
  • Delphi Technique in Research
  • Blood Pressure and Hypertension Studies
  • Nerve Injury and Rehabilitation
  • Trauma Management and Diagnosis
  • Phytochemistry and biological activities of Ficus species
  • Pneumothorax, Barotrauma, Emphysema

Boston Children's Hospital
2015-2025

Harvard University
2015-2025

Pain and Rehabilitation Medicine
2020-2025

Center for Pain and the Brain
2017-2025

Boston Children's Museum
2018-2023

Harvard University Press
2021

Barro Colorado Island
2017-2021

Beth Israel Deaconess Medical Center
2020

Hôpital Beau-Séjour
2020

American Society of Anesthesiologists
2019

WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Complications in pediatric regional anesthesia are rare, so a large sample size is necessary to quantify risk. The Pediatric Regional Anesthesia Network contains data on more than 100,000 blocks administered at 20 children's hospitals. This study analyzed the risk of major complications associated with children.This prospective, observational routine clinical practice. Data were collected every block placed by an anesthesiologist...

10.1097/aln.0000000000002372 article EN Anesthesiology 2018-08-03

Background There is heterogeneity in the names and anatomical descriptions of regional anesthetic techniques. This may have adverse consequences on education, research, implementation into clinical practice. We aimed to produce standardized nomenclature for abdominal wall, paraspinal, chest wall Methods conducted an international consensus study involving experts using a three-round Delphi method list corresponding targets. After long-list formulation by Steering Committee, first second...

10.1136/rapm-2020-102451 article EN Regional Anesthesia & Pain Medicine 2021-06-18

Summary Introduction Thoracic epidurals ( TE ) have been advocated as a superior method for controlling postoperative pain after repair of pectus excavatum with N uss procedure. However, three recent reports permanent neurologic injury the procedure concurrent analgesia raised concerns about safety this combination. Paravertebral nerve blocks PVNB are used successfully chest, but no studies available comparing and catheters in patient population. This study was conducted to compare efficacy...

10.1111/pan.12369 article EN Pediatric Anesthesia 2014-03-10

Inconsistent nomenclature and anatomical descriptions of regional anesthetic techniques hinder scientific communication engender confusion; this in turn has implications for research, education clinical implementation anesthesia. Having produced standardized abdominal wall, paraspinal chest wall techniques, we aimed to similarly do so upper lower limb peripheral nerve blocks.

10.1136/rapm-2023-104884 article EN Regional Anesthesia & Pain Medicine 2023-11-22

Neosaxitoxin (NeoSTX) is a site-1 sodium channel blocker that produces prolonged local anesthesia in animals and humans. Under Food Drug Administration-approved phase 1 Investigational New trial, the authors evaluated safety efficacy of NeoSTX alone combined with 0.2% bupivacaine (Bup) without epinephrine.The conducted double-blind, randomized, controlled trial involving healthy male volunteers aged 18 to 35 yr receiving two 10-ml subcutaneous injections. Control sites received Bup. In part...

10.1097/aln.0000000000000831 article EN Anesthesiology 2015-08-14

Paravertebral perineural blocks are used to prevent pain in the thoracoabdominal dermatomes. Traditionally, a landmark-based technique is children, while ultrasound-guided (UG) techniques being employed adult patients.To describe an UG for placement of thoracic paravertebral nerve block (TPVNB) catheters pediatric patients.Retrospective chart review series 22 patients' ages 6 months 17 years with weights from 6.25 kg 135 using transverse in-plane technique. Catheters were placed both...

10.1111/pan.12238 article EN Pediatric Anesthesia 2013-07-27

Background and objectives Documentation is important for quality improvement, education, research. There currently a lack of recommendations regarding key aspects documentation in regional anesthesia. The aim this study was to establish Methods Following the formation executive committee directed literature review, long list potential components created. A modified Delphi process then employed achieve consensus amongst group international experts This consisted 2 rounds anonymous electronic...

10.1136/rapm-2021-103136 article EN cc-by-nc Regional Anesthesia & Pain Medicine 2022-02-22

Summary Introduction The prevalence of persistent postsurgical pain in children is over 20% after major surgeries; however, data are scarce on the prevalence, character, and risk factors among undergoing common ambulatory surgeries. primary aim this study was to evaluate following pediatric surgery at 1, 3, 6 months. Secondary aims were identify characterize consequences pain. Methods ASA I‐ II , ages 1 month 16 years old, elective hypospadias repair, herniorraphy, orchiopexy, orthopedic...

10.1111/pan.13321 article EN Pediatric Anesthesia 2018-01-20

Summary Background Hip arthroscopic surgery is performed on older pediatric patients. Fascia iliaca compartment block has proven efficacy in providing analgesia following hip and can be with target location of local anesthetic below or above the inguinal ligament. The reported success ultrasound‐guided infra‐inguinal fascia lower when compared to traditional landmark technique, while reliability supra‐inguinal unreported. Aim primary aim was report results obtaining sensory changes...

10.1111/pan.13227 article EN Pediatric Anesthesia 2017-10-13

<h3>Background and Objectives</h3> Published studies have shown a benefit of regional anesthesia (RA) in preventing unplanned hospital admissions (UHAs) decreasing costs after orthopedic surgeries adults but not pediatric patients. We performed retrospective analysis to assess the effect converting from an opioid RA-based approach pain management anterior cruciate ligament (ACL) reconstruction. <h3>Methods</h3> The records patients having ACL reconstruction were reviewed. Two groups, those...

10.1097/aap.0000000000000410 article EN Regional Anesthesia & Pain Medicine 2016-01-01

Abstract Introduction Several techniques for the transversus abdominis plane ( TAP ) block have been described. The extent of sensory changes using an ultrasound‐guided posterior pTAP remains unclear in pediatric patients. primary aim this study was to report achieved with ; specifically highest thoracic dermatome anesthetized. Secondary outcomes were pain scores PS ), opioid consumption, and complications. Methods We retrospectively reviewed medical records patients less than 21 years age...

10.1111/pan.13034 article EN Pediatric Anesthesia 2017-01-18

Pain management in small infants and children is challenging. We report the use of unilateral transversus abdominis plane (TAP) catheters for analgesia following single-sided open lower abdominal surgery when epidural was undesirable a series six low-weight children. Data collection done via retrospective chart review. All attempted were successfully placed with resultant low pain scores minimal rescue analgesic medications. No complications reported related to these catheters. TAP...

10.1111/j.1460-9592.2011.03783.x article EN Pediatric Anesthesia 2011-12-26

In Brief BACKGROUND: Tonsillectomy and adenoidectomy are associated with a frequent incidence of vomiting, both in the hospital at home. We evaluated effects oral ondansetron disintegrating tablets (ODT) on at-home emesis children undergoing tonsillectomy without bilateral myringotomy tube insertion. METHODS: All patients underwent inhaled mask induction nitrous oxide, oxygen, sevoflurane. Morphine, dexamethasone, were administered to all intraoperatively. Postoperative pain was treated...

10.1213/ane.0b013e318167cc3a article EN Anesthesia & Analgesia 2008-04-01

Summary Regional anesthesia use in pediatric patients has a good safety profile. 2‐Chloroprocaine is used frequently infants due to rapid onset, lack of accumulation, and plasma degradation. We present case local anesthetic systemic toxicity following the administration 3% 2‐chloroprocaine through paravertebral catheter an infant. The episode lasted 40 s followed by complete recovery. infrequent reporting limited duration symptoms supports continued infants. Volume should be restricted...

10.1111/pan.12912 article EN Pediatric Anesthesia 2016-04-19

Summary Background Infants with long‐gap esophageal atresia ( LGEA ) undergo repeated thoracotomies for staged surgical repair known as the Foker process FP ). Associated prolonged mechanical ventilation results in exposure to high doses of opioids and benzodiazepines, weaning times ICU stays. Aim The aim this study was determine effectiveness short‐term paravertebral nerve block PVNB catheters reducing opioid/benzodiazepine effects on clinical variables. Methods medical records seventeen...

10.1111/pan.12736 article EN Pediatric Anesthesia 2015-08-14

In Brief Thoracic paravertebral nerve blocks (PVNBs) provide excellent analgesia for many surgeries. The primary aim was to estimate the complication rate, and secondary aims were information on potential clinical application of PVNBs. Data 2390 PVNBs collected. A total 625 catheters performed 468 patients, 1765 single-injection 403 patients. There 1 case local anesthetic systemic toxicity a major rate per minor 13.2%. We demonstrate low risk complications in pediatric patients receiving...

10.1213/ane.0000000000001576 article EN Anesthesia & Analgesia 2016-08-31
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