- Anesthesia and Pain Management
- Pediatric Pain Management Techniques
- Nausea and vomiting management
- Pain Management and Opioid Use
- Anesthesia and Sedative Agents
- Shoulder Injury and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Anesthesia and Neurotoxicity Research
- Ion channel regulation and function
- Spinal Hematomas and Complications
- Nerve Injury and Rehabilitation
- Peripheral Nerve Disorders
- Trauma Management and Diagnosis
- Hernia repair and management
- Vascular Malformations Diagnosis and Treatment
- Case Reports on Hematomas
- Cardiac electrophysiology and arrhythmias
- Pain Mechanisms and Treatments
- Infant Development and Preterm Care
- Pain Management and Treatment
- Music Therapy and Health
- Intraocular Surgery and Lenses
- Organ Transplantation Techniques and Outcomes
- Airway Management and Intubation Techniques
Children's Hospital of Pittsburgh
2016-2025
University of Pittsburgh
2013-2025
University of Pittsburgh Medical Center
2013-2024
John Wiley & Sons (United Kingdom)
2019
Hudson Institute
2019
John Wiley & Sons (United States)
2019
Boston Children's Hospital
2012
Summary Different transversus abdominis plane blocks techniques cause variations in postoperative analgesia characteristics. We report the use of unilateral quadratus lumborum catheter for following colostomy closure. The was placed under direct ultrasound visualization and had good outcomes: low pain scores minimal rescue analgesic medication. No complications were reported this pediatric patient. More studies are needed to evaluate effectiveness safety regional anesthesia technique.
BACKGROUND: The time between the beginning of anesthetic administration and recognition first sign malignant hyperthermia (MH) (MH onset time) could differ among drugs. METHODS: We examined signs suspected MH, drugs administered, subject age, year event in Adverse Metabolic/Musculoskeletal Reaction to Anesthesia reports North American Malignant Hyperthermia Registry. Inclusion criteria were judgment by reporting clinician that was possible or fulminant documentation when began, MH noted....
Mutations in the ryanodine receptor type 1 gene (RYR1) that encodes skeletal muscle-specific intracellular calcium (Ca(2+)) release channel are a cause of malignant hyperthermia (MH). In this study, we examined RYR1 mutations large number North American MH-susceptible (MHS) subjects without prior genetic diagnosis.
Paravertebral perineural blocks are used to prevent pain in the thoracoabdominal dermatomes. Traditionally, a landmark-based technique is children, while ultrasound-guided (UG) techniques being employed adult patients.To describe an UG for placement of thoracic paravertebral nerve block (TPVNB) catheters pediatric patients.Retrospective chart review series 22 patients' ages 6 months 17 years with weights from 6.25 kg 135 using transverse in-plane technique. Catheters were placed both...
Summary Background Ambulatory continuous peripheral nerve blocks ( CPNB s) are feasible for pediatric patients. We sought to evaluate the efficacy of s in a population. Methods This retrospective report 33‐month prospectively collected data investigates patient, parent, and nurse pain control satisfaction score PCSS ), incidence severity pain, daily analgesic consumption following discharge home with various On‐Q pumps, any complications side effects related s. Results Four hundred three...
Summary A quadratus lumborum block associated complication is a rare event. We report two cases of hematoma following the performance lumorum blocks in patients. Performing this requires additional consideration abdominal wall anatomy and patient coagulation status.
Background/Objectives: Continuous epidural analgesia is desirable for improving infant outcomes after surgeries. However, its contribution to facilitating extubation not well known. Methods: A retrospective chart review was conducted at the UPMC Children’s Hospital of Pittsburgh identify all infants who received an catheter between 2018 and 2024 required postsurgical admission Neonatal Intensive Care Unit (NICU). The study examined timing reintubation, along with associated factors, in 100...
Purpose of review Although less common than in adults, pediatric organ transplantation has seen significant recent innovations surgical techniques, perioperative management, and postoperative outcomes. These advances, which we will delve into this review, are at the forefront improving survival quality life transplant recipients. Recent findings Advances donor utilization (e.g. donation after circulatory death split-liver grafts) approaches (partial heart transplants novel multiorgan...
Single-injection paravertebral nerve blocks (PVBs) provide effective postoperative analgesia after adult laparoscopic cholecystectomy (LC). We sought to compare PVBs with local anesthetic injections at port sites in a pediatric population.Eighty-three patients (8-17 years old) scheduled for LC were randomized prospectively 2 treatment groups: the PVB group received ropivacaine 0.5% injected space and normal saline instrument sites, infiltration sites. Postoperative was provided hydromorphone...
There is an anecdotal impression that teenage patients report exaggerated postoperative pain scores do not correlate with their actual level of pain. Nurse and parental perception teenagers' can be complemented by knowledge patient behavior, catastrophizing thoughts, anxiety, mood level. Two hundred two completed the study: 56.4% female, 89.6% White, 5.4% Black, 5% other race. Patient ages ranged from 11 to 17 years (mean = 13.8, SD 1.9). The patient, parent, nurse multiple questionnaires on...
Summary Regional anesthesia techniques commonly utilized in post‐operative pain management are often considered contraindicated coagulopathic patients. We report on successful postoperative control utilizing peripheral nerve blockade after exploratory laparotomy with small bowel resection a mildly patient. In our case, complicated by abnormal PT, PTT and INR, thromboelastogram (TEG) was performed before the procedure found to be normal. An ultrasound‐guided bilateral paravertebral continuous...
Pain management in small infants and children is challenging. We report the use of unilateral transversus abdominis plane (TAP) catheters for analgesia following single-sided open lower abdominal surgery when epidural was undesirable a series six low-weight children. Data collection done via retrospective chart review. All attempted were successfully placed with resultant low pain scores minimal rescue analgesic medications. No complications reported related to these catheters. TAP...
Summary Outpatient pain management after iliac crest bone harvesting can be challenging. We report the use of home L 2 paravertebral nerve block catheter ( PVBC ) in a series five children. The scores were low, and analgesic medication consumption was minimal. No complications reported related with these catheters, patients very high control satisfaction scores. beneficial as part multimodal analgesia strategy selected pediatric patients.
Introduction: Nerve block catheters (NBCs) are increasingly used for pain management in pediatric trauma patients. While short-term efficacy has been well established, the long-term safety of NBCs is unknown. Methods/Cases: The retrospective chart review includes a cohort nine patients aged 3–15 years who received 52 peripheral nerve and epidurals management. This study aimed to investigate potential risks associated with prolonged use cases. Results: (48 4 epidural catheters) were...
Abstract Intravenous administration of acetaminophen is an alternative to the oral and rectal routes, which may be contraindicated in particular clinical settings. This randomized, placebo‐controlled study intravenous (Ofirmev, Mallinckrodt Pharmaceuticals, Bedminster, New Jersey) neonate infant patients with acute postoperative pain assessed pharmacokinetics (PK) safety, addition efficacy pharmacodynamics repeated doses administered over 24 hours. Neonate (<2 years age) who were...
Acute Interventional Perioperative Pain Service consultants have routinely placed paravertebral nerve block (PVB) catheters for the continuous release of ropivacaine following stage I microtia reconstruction with costal cartilage graft at our institution since 2010. A retrospective chart review from July 2006 was performed to compare length hospital stay, median pain score (0‐10 scale), and opioid use patients receiving PVB those historical controls. Statistical analysis included t ,...
Single injection ultrasound-guided rectus sheath blocks are used for postoperative analgesia after midline abdominal incisions, but the ultrasonographic spread of medication posterior to muscle has not been investigated.The primary goal this study was determine ultrasound-measured superiorly and inferiorly single calculate incidence cases with up subcostal margin below umbilicus. The secondary goals were correlate volume administered patient's age, weight, height, sex, body mass...
Abstract Background Adequate perioperative analgesia for pediatric abdominal transplant surgery is essential patient recovery. However, the risks of commonly used medications such as hepatotoxicity, nephrotoxicity, bleeding concerns, and poor graft results with opioids limit pain management in this population. Thoracic epidural, continuous erector spinae plane, type‐1 quadratus lumborum blocks (QLBs) have been described utilized adult population setting. The safety benefits regional...