A5024297859- Tracheal and airway disorders
- Ear Surgery and Otitis Media
- Head and Neck Surgical Oncology
- Hearing, Cochlea, Tinnitus, Genetics
- Sinusitis and nasal conditions
- Cleft Lip and Palate Research
- Hearing Loss and Rehabilitation
- Congenital Ear and Nasal Anomalies
- Cystic Fibrosis Research Advances
- Nasal Surgery and Airway Studies
- Craniofacial Disorders and Treatments
- Obstructive Sleep Apnea Research
- Dysphagia Assessment and Management
- Neuroscience of respiration and sleep
- Airway Management and Intubation Techniques
- Foreign Body Medical Cases
- Hearing Impairment and Communication
- Stress Responses and Cortisol
- Voice and Speech Disorders
- Esophageal and GI Pathology
- Respiratory and Cough-Related Research
- Noise Effects and Management
- Urinary Bladder and Prostate Research
- Thyroid Cancer Diagnosis and Treatment
- Vestibular and auditory disorders
Children's Hospital of Pittsburgh
2016-2025
University of Pittsburgh
2015-2025
University of Pittsburgh Medical Center
2016-2024
Pittsburg State University
2023
Triological Society
2020
UPMC Health System
2017
University of Alabama at Birmingham
2008-2012
University of Oklahoma
2003-2008
BackgroundMany individuals with cystic fibrosis (CF) have chronic rhinosinusitis resulting in nasal obstruction, sinus infections, and repeated surgeries. Elexacaftor-tezacaftor-ivacaftor is a highly effective modulator therapy approved for aged 6 years or older CF who at least one F508del allele other responsive mutation. The current study tests the hypothesis that ELX/TEZ/IVA improves sinonasal disease CF.MethodsThe was pre/post, observational cohort conducted two sites. Participants...
To determine whether timing of palatoplasty (early, standard, or late) is associated with speech and language outcomes in children cleft palate.Retrospective case series.Tertiary care children's hospital.Records from 733 born between 2005 2015 treated at the Cleft Craniofacial Clinic a tertiary hospital were retrospectively reviewed. Exclusion criteria repair an outside hospital, intact secondary palate, absence postpalatoplasty evaluation, syndromes, staged palatoplasty, introduction to...
Background This study aimed to compare the microbiota of pediatric patients with chronic rhinosinusitis (CRS) who are undergoing adenoidectomy treat their disease that healthy control patients. Methods Patients adenoidectomy‐only for obstructive sleep apnea (n = 50) and CRS 37) were recruited. Preoperative 22‐item Sino‐Nasal Outcome Test (SNOT‐22) or Sinus Nasal Quality Life Survey (SN‐5) collected. Each patient had samples collected from nasopharynx (adenoid bed) nasal cavity (sinus) at...
Objectives/Hypothesis To describe the clinical presentation, management, and complications associated with button battery impaction in aerodigestive tract children. Study Design Retrospective case series. Methods This multi‐institutional study, endorsed by American Society of Pediatric Otolaryngology research consortium, is a retrospective medical record review, including all children at five tertiary‐care institutions presenting batteries impacted between January 2002 December 2014. Battery...
Abstract Objective To compare the safety and efficacy of nonopioid versus opioid pain management following adenotonsillectomy (AT) among pediatric patients. Study Design An open‐label randomized controlled trial. Setting Tertiary care children's hospital. Methods Patients aged 3 to 17 years undergoing AT were eligible. Participants randomly assigned receive either acetaminophen ibuprofen (nonopioid group) or acetaminophen, ibuprofen, oxycodone (opioid group). Pain scores prevalence emergency...
Objective Describe the impact of hearing loss, tympanostomy tube placement before palatoplasty, and number tubes received on speech outcomes in children with cleft palate. Study Design Case series chart review. Setting Tertiary care children's hospital. Subjects Methods Records from 737 born between April 2005 2015 who underwent palatoplasty at a tertiary hospital were reviewed. Exclusion criteria repair an outside hospital, intact secondary palate, absence postpalatoplasty evaluation,...
Granulation tissue formation and tracheitis are common pediatric tracheostomy complications. Ciprofloxacin/dexamethasone is frequently prescribed, but the influence of social determinants on this topic unexplored.
Abstract Objective To evaluate factors impacting access to and timing of surgery in patients with submucous cleft palate (SMCP) velopharyngeal dysfunction (VPD). Study Design Retrospective cohort study. Setting Single academic medical center. Methods Patients SMCP VPD between 2004 2021 were identified. Variables included national state area deprivation index (ADI) percentiles, child opportunity (COI) categories, distance care, insurance status. χ 2 , Fisher's exact test, Wilcoxon rank‐sum,...
ABSTRACT Background Severe chronic rhinosinusitis (CRS) is a near universal manifestation of cystic fibrosis. Elexacaftor/tezacaftor/ivacaftor (ETI) an oral, small molecule, highly effective Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) corrector–potentiator drug. In people with fibrosis age > 12 years, ETI improves sinonasal symptoms, endoscopy findings, polyp size, and radiologic findings. This study evaluates changes in CRS children ages 6–12 years newly started on ETI....
Abstract Objective (1) To investigate weight as an alternative guide for trach tube choice. (2) Evaluate complications 3‐month posttracheostomy and associations with patient factors. Study Design Retrospective cohort study. Setting Single academic medical center. Methods Patients <2 years old who underwent tracheostomy placement from 2017 to 2022 were identified. Associations between characteristics, size/length, chest x‐ray (CXR) intraoperative endoscopy measurements, within 3 months...
Abstract Objective To characterize postoperative airway obstruction and evaluate management strategies in pediatric patients with cleft palate following tissue‐augmentation palatoplasty (TAP). Study Design Retrospective case series. Setting Single academic center. Methods Patients within 1 year of primary TAP between 2017 2023 were identified. Fisher's exact, Wilcoxon rank‐sum, Spearman rank correlation used to investigate the relationship type, severity, interventions, polysomnography (PSG)...
To describe the impact of timing tympanostomy tube insertion on number tubes received and complications in children with routine placement.Retrospective case series.Tertiary care children's hospital.Records from a consecutive sample 401 cleft palate were reviewed. Sixty-five patients isolated 82 lip had follow-up until 5 years age included.Tympanostomy tubes.Number tube-related complications. The hypothesis was formulated prior to data collection.Males comprised 55.8% included patients,...
To evaluate the associations between proxy measures of socioeconomic status (SES) and usage cochlear implants.Retrospective case series.Usage outcomes were measured among patients with a implant data logging at tertiary care children's hospital 2002 2017. Time per day turned on, coil off, listening to speech in noise quiet extracted from audiology records, averaging right left ear for those bilateral implants. Associations demographic factors such as insurance type median household income...
Abstract Background Chronic rhinosinusitis (CRS) is common in individuals with cystic fibrosis (CF) and marked by chronic inflammation episodes of infection that negatively impact quality life. Several studies have shown elexacaftor–tezacaftor–ivacaftor (ETI) improves symptoms examination findings CF‐CRS. The current study determines the effect ETI on sinonasal microbiota CF. Methods Sinonasal samples were collected under endoscopic visualization before after starting ETI. Samples subjected...
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Three-dimensional printed models created on a consumer level printer can be used to practice mastoidectomy and discern experience level. Current in the literature for are limited by expense or operability. The aims of this study were (1) investigate utility an inexpensive model (2) assess whether as evaluation tool surgeon performing mastoidectomy.Three-dimensional temporal bone from CT scan 7-year old patient using consumer-level stereolithography 3D raw material cost $10 each....
Background: Molecular testing (MT) enhances the diagnostic accuracy of thyroid fine-needle aspiration biopsy, reducing need for lobectomy in adult patients with indeterminate nodules (Bethesda class III/IV). However, little is known about genetic alterations pediatric carcinoma (TC). Our aim was to analyze MT results differentiated TC (DTC) cases determine associations histological and clinical features. Methods: A retrospective review identified all (aged <19 years) diagnosed DTC from 2001...