A5040295772- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac Arrest and Resuscitation
- Tryptophan and brain disorders
- Immune Cell Function and Interaction
- Infective Endocarditis Diagnosis and Management
- Nuclear Receptors and Signaling
- Foreign Body Medical Cases
- Streptococcal Infections and Treatments
- Delphi Technique in Research
- Neurogenesis and neuroplasticity mechanisms
- Mechanical Circulatory Support Devices
- Surgical Simulation and Training
- Artificial Intelligence in Healthcare
- Clinical practice guidelines implementation
- Restraint-Related Deaths
- Chronic Disease Management Strategies
- Otolaryngology and Infectious Diseases
- Esophageal and GI Pathology
University of Pittsburgh
2024-2025
University of Pittsburgh Medical Center
2024
University of Florida
2019-2022
Florida College
2019
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patients because midbrain tissue accessible postmortem. PD pathology affects both the central nervous peripheral immune systems. Therefore, we immunophenotyped blood samples presence myeloid derived suppressor cells (MDSCs) discovered that DAT
ABSTRACT Background 10–15% of children with Wilms tumor (WT) have predisposing genetic syndromes. Somatic mutations are frequently identified; however, germline pathogenic variants in AMER1 much less prevalent and associated osteopathia striata cranial sclerosis (OSCS). Methods A multicenter retrospective case series was conducted reviewing patients WT from 2012 to 2023. Results were compared published data six other children. Four female identified. Age at diagnosis ranged 5 months 8 years....
Abstract Objective (1) To investigate weight as an alternative guide for trach tube choice. (2) Evaluate complications 3‐month posttracheostomy and associations with patient factors. Study Design Retrospective cohort study. Setting Single academic medical center. Methods Patients <2 years old who underwent tracheostomy placement from 2017 to 2022 were identified. Associations between characteristics, size/length, chest x‐ray (CXR) intraoperative endoscopy measurements, within 3 months...
While management protocols of pediatric esophageal foreign bodies (EFBs) are well-delineated, resource utilization can be improved. This study's objectives were to explore hospital charges/costs for patients who present with EFBs and identify patient risk factors associated injury.
Introduction Head and neck oncologic resections with microvascular reconstruction are lengthy complex procedures inefficiencies in the operating room (OR) associated increased complications higher costs. Multidisciplinary care has become increasingly used to provide improved for patients; however, potential role of this not yet been studied head free flap procedures. Methods Patients between 2016 2022 treated before after implementation conference were included. Primary outcome was total...
Neuromodulators, such as norepinephrine and dopamine, regulate immune responses. In addition to receptor competency, select cells express machinery engage in active neurotransmitter transmission. Specifically, macrophages the (NET) dopamine transporters (DAT). However, how these - classically studied central neurons affect immunity remains poorly understood. To this end, we investigated expression function of NET DAT human macrophages. We found that monocyte-derived functional vitro. A...