A5066002657- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Pediatric Pain Management Techniques
- Airway Management and Intubation Techniques
- Anesthesia and Pain Management
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Family and Patient Care in Intensive Care Units
- Hemodynamic Monitoring and Therapy
- Nausea and vomiting management
- Patient Safety and Medication Errors
- Radiation Dose and Imaging
- Healthcare Technology and Patient Monitoring
- Assisted Reproductive Technology and Twin Pregnancy
- Medical History and Innovations
- Infant Development and Preterm Care
- Congenital Diaphragmatic Hernia Studies
- Atomic and Subatomic Physics Research
- Pain Management and Opioid Use
- Delphi Technique in Research
- Gastroesophageal reflux and treatments
- Simulation-Based Education in Healthcare
- Pectus Deformity Diagnosis and Treatment
Boston Children's Hospital
2016-2025
Harvard University
2016-2025
Baylor Scott & White Medical Center - Temple
2025
Collaborative Group (United States)
2023
Royal Australasian College of Surgeons
2023
Boston Children's Museum
2013-2022
Center for Pain and the Brain
2019-2022
Pain and Rehabilitation Medicine
2022
Boston University
2017-2021
Mayo Clinic
2017
BackgroundIn laboratory animals, exposure to most general anaesthetics leads neurotoxicity manifested by neuronal cell death and abnormal behaviour cognition. Some large human cohort studies have shown an association between anaesthesia at a young age subsequent neurodevelopmental deficits, but these are prone bias. Others found no evidence for association. We aimed establish whether in early infancy affects outcomes.MethodsIn this international, assessor-masked, equivalence, randomised,...
We used a large database of prospectively collected data on pediatric sedation/anesthesia outside the operating room provided by wide range specialists to delineate nature and frequency adverse events associated with propofol-based care.Data were Pediatric Sedation Research Consortium, collaborative group institutions dedicated improving care for children internationally. Members enrolled consecutive patients receiving sedation or procedures. The primary inclusion criterion was need some...
OBJECTIVE. We sought to use a large database of prospectively collected data on pediatric sedation and/or anesthesia for diagnostic and therapeutic procedures delineate the nature frequency adverse events that are associated with sedation/anesthesia care performed outside operating room in children. METHODS. Data were by Pediatric Sedation Research Consortium, collaborative group 35 institutions dedicated improving children internationally. Members enrolled consecutive patients who receiving...
Control of pain and stress for children is a vital component emergency medical care. Timely administration analgesia affects the entire experience can have lasting effect on child’s family’s reaction to current future A systematic approach management anxiolysis, including staff education protocol development, provide comfort in setting improve family satisfaction.
This study was designed to compare the emergence characteristics of sevoflurane with halothane anaesthesia in paediatric patients having no surgical intervention. We randomized 32 ASA I or II outpatients scheduled for magnetic resonance imaging scans receive either anaesthesia. The primary outcome measure percentage agitation, as defined by two different criteria. Time discharge from postanaesthesia care unit (PACU) and secondary recovery (SRU) were compared. Sevoflurane had a greater...
<h3>Background and Objective</h3> Ultrasound has become an increasingly popular modality in facilitating the performance of peripheral nerve blocks. There exists no literature that examines learning curve ultrasound novice. In this prospective series, we evaluated inexperienced anesthesia residents performing a simulated ultrasound-guided interventional procedure. doing so, hoped to identify reproducible patterns human errors, which could potentially aid prevention real-life iatrogenic...
Whether a component of disease process, the result acute injury, or product diagnostic therapeutic procedure, pain should be relieved and stress decreased for pediatric patients. Control children who enter into emergency medical system, from prehospital arena to department, is vital care. Any barriers that prevent appropriate timely administration analgesia child requires treatment eliminated. Although more research innovation are needed, every opportunity taken use available methods...
To determine if pediatric procedural sedation-provider medical specialty affects major complication rates when sedation-providers are part of an organized sedation service.The 38 self-selected members the Pediatric Sedation Research Consortium prospectively collected data under institutional review board approval. Demographic data, primary and coexisting illness, procedure, medications used, outcomes, airway interventions, provider specialty, adverse events were reported on a self-audited,...
Abstract Background Studies that have attempted to define the incidence of aspiration or pulmonary complications during sedation/anesthesia children with respect nil per os (NPO) status other factors are difficult because relatively infrequent rate these complications. Methods The Pediatric Sedation Research Consortium consists 42 participating institutions elective sedation services submit consecutive patient encounter information a central database. authors evaluated episodes and combined...
Summary Opioids have long held a prominent role in the management of perioperative pain adults and children. Published reports concerning appropriate, inappropriate, use these medications pediatric patients appeared various publications over last 50 years. For this document, Society for Pediatric Anesthesia appointed taskforce to evaluate available literature formulate recommendations with respect most salient aspects opioid administration The are graded based on strength evidence, consensus...
Increasing demand for pediatric procedural sedation has resulted in a marked increase provision of by critical care physicians both inside and outside the ICU. Reported experience physicians-administered is limited. We used Pediatric Sedation Research Consortium database to evaluate multicenter with propofol all settings.Review national identify provided from 2007 2012. Demographic clinical data were collected describe selection, location, delivery. Multivariable logistic regression analysis...
OBJECTIVES: Dexmedetomidine (DEX) is widely used in pediatric procedural sedation (PPS) by a variety of subspecialists. The objective our study was to describe the overall rates adverse events and serious (SAEs) when DEX various METHODS: Patients from Pediatric Sedation Research Consortium (PSRC) database were retrospectively reviewed children that received as their primary agent for elective PPS identified. Demographic clinical data, provider subspecialty, sedation-related complications...
BACKGROUND AND OBJECTIVES: Preterm and former preterm children frequently require sedation/anesthesia for diagnostic therapeutic procedures. Our objective was to determine the age at which who are born &lt;37 weeks gestational no longer increased risk adverse events. secondary describe nature incidence of METHODS: This is a prospective observational study receiving and/or procedures outside operating room by Pediatric Sedation Research Consortium. A total 57 227 patients 0 22 years were...
In Brief We designed this study to measure the effect of a small dose IV fentanyl on emergence characteristics pediatric patients undergoing sevoflurane anesthesia without any surgical intervention. Thirty-two ASA physical status I or II outpatients receiving for magnetic resonance imaging scans were enrolled and assigned in random double-blinded manner receive either placebo (saline) 1 μg/kg 10 min before discontinuation their anesthetic. The primary outcome was percentage with agitation....
BACKGROUND: Pediatric subspecialists routinely provide procedural sedation outside the operating room. No large study has reported trends in outpatient pediatric sedation. Our purpose this was to identify significant using Sedation Research Consortium. METHODS: Prospectively collected data from 2007 2018 were used for trending Patient characteristics, medications, type of providers, serious adverse events, and interventions reported. The Cochran–Armitage test trend explore association...
To evaluate the impact of obesity on adverse events and required interventions during pediatric procedural sedation.The Pediatric Sedation Research Consortium database prospectively collected sedation encounters was queried to identify patients for whom body mass index (BMI) could be calculated. Obesity defined as BMI ≥95th percentile age gender. Sedation-related outcomes, events, therapeutic were compared between obese nonobese patients.For analysis, 28,792 records eligible. A total 5,153...
OBJECTIVES: Development and validation of the Pediatric Sedation State Scale (PSSS) is intended to specifically meet needs pediatric procedural sedation providers measure effectiveness quality care. METHODS: The PSSS content was developed through Delphi methods utilizing leading experts published guidelines on in children. Video clips were created presented study participants, who graded state patients during procedures by using evaluate inter- intrarater reliability determining intraclass...
Procedural sedation/anesthesia outside the operating room for a variety of procedures is well described with an overall low adverse event rate in certain settings. Adverse associated procedural gastrointestinal have been described, albeit small, single-center studies wide variance outcomes. Predictors such outcomes are unclear. We aimed to estimate prevalence children undergoing esophagogastroduodenoscopy, colonoscopy, or both identify predictors event.Retrospective analysis Pediatric...
Neosaxitoxin (NeoSTX) is a site-1 sodium channel blocker that produces prolonged local anesthesia in animals and humans. Under Food Drug Administration-approved phase 1 Investigational New trial, the authors evaluated safety efficacy of NeoSTX alone combined with 0.2% bupivacaine (Bup) without epinephrine.The conducted double-blind, randomized, controlled trial involving healthy male volunteers aged 18 to 35 yr receiving two 10-ml subcutaneous injections. Control sites received Bup. In part...