A5008388060- Anesthesia and Pain Management
- Pediatric Pain Management Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Spine and Intervertebral Disc Pathology
- Erythrocyte Function and Pathophysiology
- Blood groups and transfusion
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Pain Management and Opioid Use
- Immunodeficiency and Autoimmune Disorders
- Hemoglobinopathies and Related Disorders
- Muscle Physiology and Disorders
- Nuclear Structure and Function
- Neonatal Health and Biochemistry
- Spinal Fractures and Fixation Techniques
- Airway Management and Intubation Techniques
- Neurosurgical Procedures and Complications
- Cardiac Structural Anomalies and Repair
- Clusterin in disease pathology
- Shoulder Injury and Treatment
- RNA modifications and cancer
- Tracheal and airway disorders
- Blood disorders and treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
Nationwide Children's Hospital
2016-2025
The Ohio State University
2016-2025
Arkansas Children's Hospital
2025
University of Arkansas for Medical Sciences
2025
University of Pittsburgh Medical Center
2015
University of Pittsburgh
2012
Case Western Reserve University
2006-2011
The University of Texas Southwestern Medical Center
2007
Ente Ospedaliero Ospedali Galliera
1964-1984
Neonates and infants have decreased metabolic capacity for amide local anesthetics increased risk of anesthetic toxicity compared to the general population. Chloroprocaine is an ester that has extremely short plasma half-life in as well adults. Existing reports support safety efficacy continuous chloroprocaine epidural infusions neonates young during intraoperative period. Despite this, infusion may be under-utilized method postoperative analgesia this patient In particular, it improve pain...
Pain management following posterior spinal fusion (PSF) in pediatric patients can present significant challenges for clinicians. Opioids continue as the primary modality managing postoperative pain these patients, despite well-known concerns regarding their adverse effect profile such risk of dependence or abuse. Therefore, there has been increased focus on multimodal analgesic approaches that incorporate non-opioid medications, non-pharmacologic techniques, and regional anesthesia. Commonly...
ABSTRACT Introduction Preliminary clinical studies have demonstrated that clonidine is an effective adjuvant to spinal anesthesia in neonates and infants. However, the conducted previously had a limited cohort size of 80–100, potentially limiting accurate measure its safety. Methods The current study retrospectively examines our 5–6‐year experience with as large Results included 1420 patients ranging age from newborn 36 months (median 7 months). Ninety‐five percent tolerated without...
Although the Nuss procedure provides excellent cosmetic results for correction of pectus excavatum, provision analgesia following such procedures can be challenging.The current study retrospectively reviews our experience over a 2.5 year period with thoracic epidural (TE), paravertebral blockade (PVB), and intravenous opioids delivered via patient-controlled (PCA) to provide postoperative analgesia.The cohort included 30 patients (mean age = 15.6 ± 1.5 years), 15 whom were treated PCA, 8 TE,...
Background: There continues to be focus on the value of regional and neuraxial anesthetic techniques when combined with general anesthesia improve postoperative analgesia. The reported advantages include decreased opioid requirements, medication-related adverse effects, hospital length stay, increased patient satisfaction. Orthopedic procedures hip may amenable such as there is significant pain requirement for admission administration parenteral opioids. Given surgical site, various used...
Umbilical hernia repair is a common pediatric surgical procedure. While opioid analgesics are feasible option and have long been mainstay in the pharmacological intervention for pain, effort to improve care limit opioid-related adverse effects has led use of alternative techniques, including regional anesthesia. The current study prospectively compares analgesic efficacy three caudal epidural blockade, peripheral nerve local wound infiltration, double-blinded study.A total 39 patients...
<h3>Background and Objectives</h3> Perineural dexamethasone has been demonstrated to extend postsurgical analgesia after peripheral nerve blockade in adults. The mechanism of action as a regional anesthetic adjuvant is unclear intravenous shown have similar analgesic efficacy perineural dexamethasone. not previously explored the pediatric population. <h3>Methods</h3> After obtaining informed consent, children (aged 10–18 years) presenting for arthroscopic knee surgery with femoral block were...
Home peripheral nerve catheters (PNCs) have become common practice for adult patients after major orthopedic surgery. However, use in pediatric is a recent application.The purpose of this study was to review the demographics and outcomes receiving PNC at our institution.This retrospective included from October 2012 through 2014 undergoing procedures with placed postoperative pain management.A total 118 aged 3.2-25.3 years were identified. The types femoral (80.5%), interscalene (11.9%),...
Background: Femoral nerve blockade (FNB) provides effective postoperative analgesia in children undergoing arthroscopic knee surgery as evidenced by their opioid-sparing effects and decreased pain scores. Increasing the local anesthetic concentration peripheral for adults orthopedic has been shown to be beneficial, increasing block success rate, providing a longer duration of analgesia. The effect extremity blocks remains largely unexplored. Methods: We retrospectively evaluated...
OBJECTIVES: We pursued the use of regional analgesia (RA) to minimize postoperative opioids. Our aim was increase RA for eligible surgical procedures in NICU from 0% 80% by June 30, 2019. METHODS: A multidisciplinary team determined eligibility criteria, developed an extensive process map, implemented comprehensive education, and a structured communication pain management plans. Daily rounds provided opportunity collaborative comanagement. An additional 30 minutes catheter placement added...
To perform a single institution review of spinal instead general anesthesia for pediatric patients undergoing surgical procedures. Spinal success rate, intraoperative complications, and postoperative outcomes including unplanned hospital admission emergency department visits within seven days are reported.
Abstract: Post-dural puncture headache (PDPH) is a common adverse outcome following of the dura. It can occur after inadvertent dural during epidural catheter placement or diagnostic therapeutic LP. The incidence PDPH in pediatric patients has been estimated at 1– 15% depending on patient factors (age, gender, body mass index) and needle (size bevel/point type). larger gauge, higher PDPH. Various options have proposed to treat including observation, bed rest, hydration, caffeine,...
The use of regional anesthesia techniques continues to expand in a wide variety surgical procedures as the benefits and safety are increasingly appreciated. Limb-lengthening often associated with significant postoperative pain high opioid requirements which may impact patient's recovery increase risk chronic long-term use.The current study retrospectively reviews our experience utilizing novel peripheral nerve catheter (PNC) protocol for management patients undergoing elective...
For surgical procedures involving the hip and femur, various regional anesthetic techniques may be used to provide analgesia. Although there has been an increase in use of lumbar plexus block (LPB), technique time consuming associated with complications. Suprainguinal fascia iliaca compartment (FICB) is a potentially easier safer alternative. The current study prospectively compares LPB suprainguinal FICB.This prospective, double-blinded, randomized, included patients undergoing elective...