Summary Background Duchenne muscular dystrophy ( DMD ) possesses many potential challenges for anesthetic care. Invasive and noninvasive procedures with corresponding sedation or general anesthesia are frequent necessary affected patients. There remains a need better agent agents procedural in patients comorbid diseases. This study prospectively evaluated combination of ketamine two different doses dexmedetomidine during muscle biopsy . Methods Dexmedetomidine 1.0 0.5 μg·kg −1 was...

Over the past few years, there has been a change in clinical practice with transition to use of cuffed instead uncuffed endotracheal tubes (ETTs) pediatric patients. These changes have led concerns regarding unsafe intracuff pressures patients, which may result postoperative morbidity. To avoid these issues, it is generally suggested that pressure be maintained at ≤30 cmH2 O. The current study prospectively assesses related alterations head and neck position patients.Patients less than 18...

Summary Background During perioperative care, the continuous measurement of blood pressure ( BP ) provides superior physiologic monitoring to intermittent techniques. However, such requires placement an intraarterial catheter, which may be time‐consuming or associated with adverse events and technical difficulty. A noninvasive, device has been studied in adult population. This study prospectively assesses its accuracy pediatric patients, weighing 20–40 kg. Methods The technology evaluated is...

Abstract Background Adenotonsillectomy is one of the most commonly performed operative procedures in children. It imperative to find efficient and cost‐effective methods practice facilitate operating room management while maintaining patient safety. We investigated efficiency two different approaches tracheal extubation pediatric patients following adenotonsillectomy at tertiary care hospitals with large surgical volumes. The primary aim study was determine difference time according...

Summary Background With the development of newer polyurethane cuffed endotracheal tubes ( cETT s), there has been a shift in clinical practice among pediatric anesthesiologists. Despite improvements design, excessive inflation cuff can still compromise tracheal mucosal perfusion. Several perioperative factors affect intracuff pressure CP ), and is no consensus on safe patients undergoing repair congenital cardiac disease CHD ) utilizing cardiopulmonary bypass CPB ). In current study, was...

OBJECTIVES: Controlled hypotension is one means to limit or avoid the need for allogeneic blood products. Clevidipine a short-acting, intravenous calcium channel antagonist with half-life of 1 3 minutes due rapid metabolism by non-specific and tissue esterases. To date, there are no prospective evaluations clevidipine in pediatric population. We prospectively evaluated dosing requirements, efficacy, safety ontrolled during spinal surgery neuromuscular scoliosis METHODS: Patients undergoing...

Life-threatening hypoxemia during tracheal intubation is more likely to occur in children than adults due its unique physiological and anatomical nature. Fiberoptic widely performed with difficult airways. However, mastery of fiberoptic requires substantial training, novice trainees need attempt at high risk respiratory-related adverse events. Therefore, a safer method traditional for airways desirable anesthesia trainees. This study aimed compare the efficacy video-assisted (VAFI) that...

Delayed identification of infiltration and dysfunction peripheral intravenous (PIV) access can lead to serious consequences during general anesthesia in children. This preliminary study aimed describe the application precordial Doppler ultrasound children detect confirm correct PIV evaluate accuracy this method.This was a single-center, that conducted (<18 years) who were scheduled for elective surgeries between October 2019 March 2020. Rater anesthesiologists judged change sound (S test)...

The neuronal ceroid lipofuscinoses (NCL) are a group of inherited, autosomal recessive, and progressive neurodegenerative diseases, which result from an enzymatic defect or the deficiency transmembrane protein, leading to accumulation lipopigments (lipofuscin) in various tissues. NCL results impairment function several end-organs including central nervous system with loss cognitive motor function, myoclonus, intractable seizures. Additional involvement includes cardiovascular arrhythmias...

Cold agglutinins are auto-antibodies, usually of the IgM class, that present in low titers blood normal individuals. They generally no clinical significance healthy patients because they active only at extremely temperatures (less than 10 °C). However, when high titers, during periods hypothermia, may have impact. We a child presenting for surgery congenital heart disease, whom agglutination was noted hypothermia while on cardiopulmonary bypass (CPB). The history cold agglutinin disease is...

This case report highlights the use of an integrated Dual Recording System (iDRS) to document and analyze airway management. The iDRS combines video laryngoscopy a wide-angle camera capture dual-view recordings larynx operating room during procedures. We utilized this system in 5-month-old boy with difficult who underwent pulmonary artery banding under general anesthesia. Retrospective analysis showed discrepancies between written information findings, including differences desaturation...

Rocuronium-induced injection pain causes withdrawal movements. These movements may cause accidental disruption of indwelling needles. Generic rocuronium contains low-acid concentration buffer solution compared with original rocuronium. In animal experiments, it has been suggested that the difference alleviate pain. The purpose this study was to identify between and generic in pediatric population.Patients ranging age from 1 15 years, American Society Anesthesiologists physical status I or...

Giant axonal neuropathy (GAN) is a rare, autosomal recessive, progressive neurodegenerative disorder affecting both the central and peripheral nervous systems. The aberrant accumulation of cytoskeletal-associated proteins causes neurodegeneration resulting in motor sensory dysfunction. Given invariable involvement neuromuscular system, anesthetic care frequently needed to correct orthopedic sequelae disorder. We present 12-year-old girl with GAN who required for posterior spinal fusion treat...

Cold agglutinins are auto-antibodies, usually of the IgM class, that present in low titers blood normal individuals. They generally no clinical significance healthy patients because they active only at extremely temperatures (less than 10 °C). However, when high titers, during periods hypothermia, may have impact. We a child presenting for surgery congenital heart disease, whom agglutination was noted hypothermia while on cardiopulmonary bypass (CPB). The history cold agglutinin disease is...