A5061278713- Traumatic Brain Injury Research
- Mitochondrial Function and Pathology
- Family and Disability Support Research
- Metabolism and Genetic Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Childhood Cancer Survivors' Quality of Life
- ATP Synthase and ATPases Research
- Psychosomatic Disorders and Their Treatments
- Action Observation and Synchronization
- Cognitive Functions and Memory
- Intensive Care Unit Cognitive Disorders
- Educational and Psychological Assessments
- Autism Spectrum Disorder Research
- Neonatal Respiratory Health Research
- Cardiac Arrest and Resuscitation
- Genetics and Neurodevelopmental Disorders
Edmond and Lily Safra Children's Hospital
2015-2023
Sheba Medical Center
2017-2023
Academic College of Tel Aviv-Yafo
2017-2023
Patients with single large-scale mitochondrial DNA (mtDNA) deletion syndromes (SLSMDs) usually present multisystemic disease, either as Pearson syndrome in early childhood or Kearns-Sayre later life. No disease-modifying therapies exist for SLSMDs. We have developed a method to enrich hematopoietic cells exogenous mitochondria, and we treated six patients SLSMDs through compassionate use program. Autologous CD34 + were augmented maternally derived healthy technology termed augmentation...
Memory deficits are a common sequelae following childhood traumatic brain injury (TBI), which often have serious implications on age-related academic skills. The current study examined verbal memory performance using the Rey Auditory Verbal Learning Test (RAVLT) in pediatric TBI sample. abilities as well effect of age at-testing were examined. A sample 67 children severe (age average = 12.3 ± 2.74) and matched controls evaluated RAVLT. Age at assessment was two groups: above below 12 years...
Objective: To test the efficacy of Mitochondrial Augmentation Therapy (MAT) to improve physiological and metabolic status a patient with Kearns-Sayre syndrome (KSS) Background: KSS is defined as progressive retinitis pigmentosa external ophthalmoplegia occurring at childhood due de-novo mtDNA deletions. Other systems may be involved over time including hearing, heart, central nervous system, skeletal muscles, endocrine glands kidneys. There no available treatment for KSS. Previous studies...
A paucity of data exists regarding the duration post-traumatic amnesia (PTA) as a predictor cognitive functioning among children after traumatic brain injury (TBI). The study aimed to assess relationship between PTA and areas neurocognitive function pediatric population in sub-acute phase recovery rehabilitation.Data were collected from medical files on 103 aged 5.5-16.5 hospitalized at rehabilitation department with diagnosis moderate-severe TBI (msTBI) years 2004-2019. Children Orientation...
This work presents a case of young woman with apraxia and severe body scheme disorder, 10 years after childhood frontal occipitoparietal brain injury. Despite specific limitations, she is independent in performing all activities daily living. A battery tests was administered to evaluate praxis representations. Specifically, the Hand Laterality Test used compare RS's dynamic representation that healthy controls (N = 14). Results demonstrated impairment, revealed deficits accuracy latency...
This paper presents a follow-up of child with Balint’s syndrome over more than decade. The patient experienced traumatic brain injury before age 12, resulting in bilateral occipito-parietal infarctions and clinical presentation syndrome. Neuropsychological assessments at three time points showed average verbal abilities alongside persistent difficulties visual orientation, mirrored the patient’s daily life. Her outstanding compensatory face these impairments are discussed respect to...