A5070091003- Coenzyme Q10 studies and effects
- Advanced Drug Delivery Systems
- Mitochondrial Function and Pathology
- Ocular Surface and Contact Lens
- Safe Handling of Antineoplastic Drugs
- Prion Diseases and Protein Misfolding
- Retinal Diseases and Treatments
- Advancements in Transdermal Drug Delivery
- Metalloenzymes and iron-sulfur proteins
- Hernia repair and management
- Ocular Oncology and Treatments
- Pharmacological Effects of Natural Compounds
- Biosimilars and Bioanalytical Methods
- Colorectal Cancer Treatments and Studies
- Plant biochemistry and biosynthesis
- Block Copolymer Self-Assembly
- Ocular Diseases and Behçet’s Syndrome
- Gastrointestinal motility and disorders
- Fatty Acid Research and Health
- Retinal Imaging and Analysis
- Ginkgo biloba and Cashew Applications
- Biochemical Analysis and Sensing Techniques
- Infant Nutrition and Health
- Microbial Metabolites in Food Biotechnology
- Pesticide Residue Analysis and Safety
Trakya University
2020-2024
Sağlık Bilimleri Üniversitesi
2023-2024
Fatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi
2024
Balıkesir University
2024
University of Turin
2023
Creative Commons
2023
Ankara University
2016-2019
Ümraniye Eğitim ve Araştırma Hastanesi
2016
To investigate the swept-source optical coherence tomography (SS-OCT) and SS-OCT angiography (SS-OCTA) findings in circumscribed choroidal hemangioma (CCH) before after treatment with transpupillary thermotherapy (TTT). The clinical records of 21 eyes having CCH imaged SS-OCT/SS-OCTA between September 2018 December 2022 were evaluated. examination showed dome-shaped appearance (100%), shadowing expansion structures subretinal fluid (66.7%), intraretinal edema/schisis (33.3%), retinal pigment...
Recent reports have demonstrated that refrigerated bevacizumab can be stored for up to 3 weeks at 4 degrees C without loss of efficacy. There been no previous addressing bevacizumab's sterility when and used as multiple doses from a single-use vial.To evaluate the vial.Four groups vials were simulate storage use conditions bevacizumab. Each group contained 11 0.2 mL One sample each was cultured once day 37 10 days; one left 15 days. MacConkey agar, blood thioglycollate broth, Sabouraud...
Purpose. To evaluate the relationship between internal carotid artery (ICA) stenosis and subfoveal choroidal thickness (SFCT) in elderly population. Methods. A total of 42 eyes 21 patients with more than 70% ICA (Group 1) on one side less 2) other were recruited for this study. was diagnosed using both B-mode Doppler ultrasound. The two groups compared terms percentage stenosis, SFCT measurements, intraocular pressure, ocular perfusion refractive error, peak systolic velocity. Eyes examined...
S-adenosyl-L-methionine (SAMe) is an endogenic methyl donor naturally present in all living cells; it has high water solubility, but its bioavailability low oral administration due to the first pass effect liver.The aim of this study prepare colon targeted chitosan nanoparticles containing SAMe by ionic gelation.In preparation formulations, effects concentration, tripolyphosphate (TPP) concentration and amount on specifications such as particle size, zeta potential, encapsulation efficiency,...
To prospectively investigate the impact of various hormone replacement therapies (HRT) on ocular surface and tear function tests.A total 70 women in postmenopausal period were enrolled study. The groups consisted 16 who not HRT (group 1), 29 with tibolone 2) 25 received estradiol plus medroxyprogesterone acetate treatment 3). All patients underwent film break-up time (TFBUT), Schirmer's test conjunctiva cytology at enrollment 6 months' follow-up.Patients group 2 showed improved TFBUT results...
Background/aim: Methotrexate (MTX) is a folic acid antagonist that widely used to treat osteosarcoma, leukemia, breast cancer, and autoimmune inflammatory diseases. The most important concerns with MTX are its poor solubility high toxicity, particularly in liver cells. To enhance minimize we encapsulated niosomes investigated hepatotoxicity mechanisms using genetic biomarkers. Materials methods: Niosomes were successfully prepared modified thin film method, the monodisperse smallsized...
6-Mercaptopurine (6-MCP) is an antiproliferative purine analog used in acute lymphoblastic leukemia, non-Hodgkin lymphoma, and inflammatory bowel disease (Crohn's disease, ulcerative colitis). Although 6-MCP has the great therapeutic potential for cancer immunosuppressant-related diseases, not readily soluble water, presents a high first-pass effect, short half-life (0.5–1.5 h), implies low bioavailability (16%). On contrary, solid lipid nanoparticles (SLNs) are prepared from lipids at room...
Addressing obesity is a critical health concern of the century, necessitating urgent attention. L-carnitine (LC), an essential water-soluble compound, plays pivotal role in lipid breakdown via β-oxidation and facilitates transport long-chain fatty acids across mitochondrial membranes. However, LC’s high hydrophilicity poses challenges to its diffusion through bilayers, resulting limited bioavailability, short half-life, lack storage within body, mandating frequent dosing. In our research, we...
Abstract Background Laparoscopic hernia repair has been accepted as first-line treatment for inguinal by major surgical institutions today, with low complication and recurrence rates. The aim of this prospective clinical study, we compared two different laparoscopic approaches in terms technical ease, patients' early postoperative quality life, pain management, Method Patients who were planned to undergo randomized operated total extraperitoneal (TEP) extended view (eTEP) methods July August...
This study presents the development and validation of a novel high-performance liquid chromatography (HPLC) method for quantification rimantadine in pharmaceutical formulations.Rimantadine, an antiviral drug primarily used treatment influenza A, necessitates effective analytical methods quality control.Our HPLC employs reverse-phase column with mobile phase comprising acetonitrile 15mM phosphate buffer (pH 3.0) ratio 65:35 water, under isocratic elution conditions.The detection was carried...