A5043061476- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Biosensors and Analytical Detection
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced biosensing and bioanalysis techniques
- Electrowetting and Microfluidic Technologies
- Electrohydrodynamics and Fluid Dynamics
- Characterization and Applications of Magnetic Nanoparticles
- 3D Printing in Biomedical Research
- Reproductive tract infections research
- SARS-CoV-2 detection and testing
- Medical Imaging Techniques and Applications
- Magnetic and Electromagnetic Effects
- Analytical Chemistry and Sensors
- Syphilis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
- Analytical Chemistry and Chromatography
- Polymer Surface Interaction Studies
- Bacterial Infections and Vaccines
- Agricultural Innovations and Practices
- Advanced Chemical Sensor Technologies
- Advanced Biosensing Techniques and Applications
- Electrochemical sensors and biosensors
- Metal and Thin Film Mechanics
- Bacteriophages and microbial interactions
Stockholm University
2022-2025
University of Hull
2014-2023
MIREA - Russian Technological University
2022
National Institute for Materials Science
2005-2006
Imperial College London
2002-2006
Philipps University of Marburg
2002
The ability to separate living cells is an essential aspect of cell research. Magnetic separation methods are among some the most efficient for bulk separation. With development microfluidic platforms within biotechnology sector, design miniaturised magnetic sorters desirable. Here, we report continuous sorting loaded with nanoparticles in a device. Cells were passed through chamber and deflected from direction flow by means field. Two types studied, mouse macrophages human ovarian cancer...
The separation of magnetic microparticles was achieved by on-chip free-flow magnetophoresis. In continuous flow, particles were deflected from the direction laminar flow a perpendicular field depending on their susceptibility and size rate. Magnetic could thus be separated each other nonmagnetic materials. introduced into microfluidic chamber, deflection studied under microscope. 2.0 4.5 μm in diameter with susceptibilities 1.12 × 10-4 1.6 m3 kg-1, respectively. 4.5-μm larger further than...
Magnetically labelled cells are finding a wealth of applications for in vitro analysis as well vivo treatments. Sorting into subpopulations based on their magnetite loading is an important step such procedures. Here, we study the sorting monocytes and macrophages which internalise nanoparticles to different extents endocytotic capacity. Macrophages featured high activity were found between 4 60 pg iron per cell. They successfully sorted five narrow distributions via on-chip free-flow...
An extremely versatile microfluidic device is demonstrated in which multi-step (bio)chemical procedures can be performed continuous flow. The system operates by generating several co-laminar flow streams, contain reagents for specific (bio)reactions across a rectangular reaction chamber. Functionalized magnetic microparticles are employed as mobile solid-supports and pulled from one side of the chamber to other use an external field. As particles traverse reagent binding washing steps on...
The continuous flow focussing and manipulation of particles cells are important factors in microfluidic applications for performing accurate reproducible procedures downstream. Many particle methods require complex setups or channel designs that can limit the process its applications. Here, we present diamagnetic repulsion as a simple means objects flow, based only on their intrinsic properties without requirement any label. Diamagnetic polystyrene were suspended paramagnetic medium pumped...
Processing of stool samples using an IFAST microfluidic device for the genetic analysis infectious pathogens such as<italic>H. pylori</italic>.
Agroathelia rolfsii (A. rolfsii) is a fungal infection and poses significant threat to over 500 plant species worldwide. It can reduce crop yields drastically resulting in substantial economic losses. While conventional detection methods like PCR offer high sensitivity specificity, they require specialized expensive equipment, limiting their applicability resource-limited settings the field. Herein, we present an integrated workflow with nucleic acid extraction isothermal amplification...
A microfluidic device for counting and sizing particles particle agglomerates based on laser light scattering is demonstrated. The were confined hydrodynamically passed through a focused beam. Scattering at two different angles, 15° 45°, was detected. At an acquisition rate of 10 kHz, throughput 150 s−1 achieved. intensity found to depend volume 2 9 µm diameter particles. Size discrimination with ratio 1 : accomplished. In addition, the signals formed in particle-enhanced immunoassay...
We have developed an integrated microfluidic platform for producing 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) in continuous flow from a single bolus of radioactive isotope solution, with constant product yields achieved throughout the operation that were comparable to those reported commercially available vessel-based synthesisers (40–80%). The system would allow researchers obtain radiopharmaceuticals dose-on-demand setting within few minutes. flexible architecture platform, based on...
A chip design inspired by the “Snakes-and-Ladders” boardgame was used to deposit a bilayer of polyelectrolytes onto magnetic droplets within 30 seconds.
We demonstrate for the first time direct stereolithographic 3D printing of an extrinsically self-healing composite, comprised commercial photocurable resin modified with anisole and PMMA-filled microcapsules. The composites solvent-welding based autonomous to afford 87% recovery initial critical toughness. This work illustrates potential fabricate user-defined structures, avoiding need extensive rheological optimization inks, like in direct-write printing. Importantly, this also demonstrates...
Annually, approximately 174 million people globally are affected by Trichomonas vaginalis (T. vaginalis) infection. Half of these infections occur in resource-limited regions. Untreated T. associated with complications such as pelvic inflammatory disease and adverse pregnancy outcomes mostly seen women. In regions, the World Health Organization (WHO) advocates for syndromic case management. However, this can lead to unnecessary treatment. Accurate diagnosis is required effective prompt...
A glass microfluidic device has been functionalized with photoactive porphyrins for performing reactions which are mediated by singlet molecular oxygen. The resulting was used to investigate the photochemical oxidation of cholesterol, α-terpinene, and citronellol under flow conditions, results were compared similar batch reactions.