A5015953033- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Retinopathy of Prematurity Studies
- Genetic Syndromes and Imprinting
- Advanced Neuroimaging Techniques and Applications
- Genetics and Neurodevelopmental Disorders
- Cerebral Palsy and Movement Disorders
- Child and Adolescent Health
- Birth, Development, and Health
- Cognitive Abilities and Testing
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Spatial Cognition and Navigation
- Sociology and Education Studies
- Family and Disability Support Research
- Infant Health and Development
- Attention Deficit Hyperactivity Disorder
- Pregnancy and Medication Impact
- Advanced MRI Techniques and Applications
- Neuroscience of respiration and sleep
- Maternal Mental Health During Pregnancy and Postpartum
- Cognitive and developmental aspects of mathematical skills
- Health and Medical Studies
- Congenital Diaphragmatic Hernia Studies
Salzburg University of Applied Sciences
2025
Karolinska Institutet
2010-2020
Karolinska University Hospital
2005-2019
Aim : The aim of this study was to explore whether children born preterm have deficient executive functions (EF) in comparison with at full term, and, if so, is dependent on inferior intelligence scores and can be correlated specific neonatal risk factors gender. Methods In a population‐based study, the 182 (birthweight less than 1500 g, VLBW) 125 controls from Stockholm Neonatal Project were assessed 5± y neuropsychological test battery (Nepsy 1990). Results surpassed VLBW tests (EF), even...
Summary Background Prader–Willi syndrome (PWS) is a neurogenetic disorder characterized by muscular hypotonia, psychomotor delay, feeding difficulties and failure to thrive in infancy. GH treatment improves growth velocity body composition. Research on the effects of development infants with PWS limited. Objective To evaluate toddlers during compared randomized controls. Design/patients Forty‐three were evaluated at baseline. Twenty‐nine them into group ( n = 15) receiving 1 mg/m 2 /day or...
In a population-based follow-up study (the Stockholm Neonatal Project), 182 children with birthweight of 1500 g or less (very-low birthweight: VLBW) and control group 125 born healthy at term were examined the Wechsler Preschool Primary Scale Intelligence-Revised (WPPSI-R) neuropsychological test battery (Nepsy) 5 1/2 years age. The WPPSI-R results VLBW fell well within normal range: full-scale IQ 95.7, verbal subscale 99.9, performance 91.6. Nevertheless, had significantly better than which...
The Stockholm Neonatal Project involves a prospective, cross-sectional, population-based, cohort monitored for 12 to 17 years after birth; it was started with the aim of investigating long-term structural correlates preterm birth and comparing findings reports on similar cohorts.High-resolution anatomic diffusion tensor imaging data measuring in 30 directions were collected by using 1.5-T MRI scanner. A total 143 adolescents (12.18-17.7 age) participated study, including 74 formerly infants...
In a population‐based follow‐up study (the Stockholm Neonatal Project), 182 children with birth weight of 1500g or less (very‐low weight: VLBW) and control group 125 born healthy at term were examined the Wechsler Preschool Primary Scale Intelligence‐Revised (WPPSI‐R) neuropsychological test battery (Nepsy) 5½ years age. The WPPSI‐R results VLBW fell well within normal range: full‐scale IQ 95.7, verbal subscale 99.9, performance 91.6. Nevertheless, had significantly better than which could...
Abstract Background Prader–Willi syndrome (PWS) is a multisystem genetic disorder characterized by short stature, muscular hypotonia, hyperphagia, obesity, maladaptive behaviour, hypogonadism and partial growth hormone (GH) deficiency (GHD). Severe GHD of other aetiologies has been shown to affect mood quality life negatively, there are reports improvements with GH replacement. We have studied cognitive, emotional, physical social parameters in PWS adults at baseline, during after treatment....
The aim of this study was to investigate long-term cognitive outcome in a cohort 18-year-olds born preterm and previously assessed at the age 5.5.We tested 134 adolescents with very low birthweight <1500 g 94 term-born controls comprehensive battery 18 years age. subdivided into 73 extremely preterm, 42 19 moderately infants gestational ages 23-27, 28-31 32-36 weeks, respectively. group dominated by small for age.Very performed on par controls. In contrast, displayed inferior results all...
Background: Mobile health (mHealth) technology can support therapy adherence and self-management of people with multiple sclerosis (MS), but mHealth solutions tailored for the Austrian context are currently lacking. Objectives: This study aimed to evaluate usability, user experience acceptance Swiss “MS Active App” in an setting, identify transferable requirements design implications. Methods: Nine MS used App one week as part their individual physiotherapy occupational therapy. Data...
Visual-motor development and executive functions were investigated with the Bender Test at age 5½ years in 175 children born preterm 125 full-term controls, within longitudinal Stockholm Neonatal Project. Assessment also included WPPSI-R NEPSY neuropsychological battery for ages 4-7 (Korkman, 1990). protocols scored according to Brannigan & Decker (2003), Koppitz (1963) a complementary scoring system (ABC), aimed developed this study. results by all three systems strongly related overall...
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Abstract Aim This study evaluated whether maternal mood disorders (MMD), particularly bipolar disorder, and lithium treatment during pregnancy influenced the neonatal health cognition of children born from 2006 to 2010. Methods Our at Karolinska University Hospital, Stockholm, Sweden, focused on women with without their children. Information pharmacotherapy, mental health, delivery complications was retrospectively collected electronic patient records. Children were tested in a blinded...
Cognitive outcome after preterm birth is heterogeneous, and group level analyses may disguise individual variability in development. Using a person-oriented approach, this study investigated cognitive patterns developmental trajectories from preschool age to late adolescence. As part of prospective longitudinal study, 118 adolescents born preterm, with weight < 1,500 g, participated neuropsychological assessments at 5½ years 18 years. At each age, four indices, two tapping general ability...
Background: There is a high prevalence of cognitive dysfunction in very low birthweight (500-1250 g) infants (VLBW). Understanding long-term risk factors associated with development preterm children requires longitudinal characterization. Thus, follow-up evaluations-- including identification risks and resilience influences--are important to promote health abilities born preterm. Aim: To examine changes from birth until 11 years age birthweight. Method: 24 VLBW infants, at the Karolinska...
<b>Background:</b> Preterm infants with chronic lung disease (CLD) had impaired cognitive development and poorer eye-hand coordination at 10 months of age. <b>Aims:</b> To study whether this effect CLD persisted until school age the severity affected outcome. <b>Method:</b> Cognition visual-motor skills were examined (Wechsler preschool primary scale intelligence, tests from Nepsy scale) in 60 very preterm children, without intraventricular haemorrhage or periventricular leucomalacia, 5.5...
Follow-up studies of preterm children have reported a range cognitive deficits, particularly in executive functions, visuospatial abilities, and learning. However, few researchers adopted person-oriented approach, exploring individual neuropsychological profiles. The aim this study was to identify typical profiles among control children, respectively. A second investigate if at age 5½ might be associated with perinatal medical risk factors. As part the longitudinal Stockholm Neonatal...
Prader-Willi syndrome is a neurogenetic disorder, with characteristics such as obesity, short stature, muscular weakness, intellectual deficiencies and deviant social behaviour. This study evaluated whether growth hormone treatment of children resulted in possible lasting effects on their cognition behaviour.We randomised six girls 13 boys to either group or control group. The received (Genotropin(®) 0.033 mg/kg/day) for 2 years, while the did not receive first year then double dose second...
The aim of the study was to investigate cognitive outcomes at 6.5 years in children born very preterm, relation neonatal characteristics and 2.5-year neurodevelopment.A prospective cohort, with gestational age 22.3-31.9 weeks, 2004-2007, were examined 2.5 Bayley Scales Infant Toddler Development (Bayley-III) (n = 100) Wechsler Intelligence 91).Neonatal factors independently related 6.5-year outcome age, retinopathy prematurity treated persistent ductus arteriosus. Bayley-III scores explained...
To assess visual-motor integration in young adults previously included a prospective study on the incidence of retinopathy prematurity (ROP).The encompassed 59 preterm individuals, born 1988-1990, with birth weight ≤1500 g, and 44 full-term controls, aged 25-29 years. Ophthalmological examination, including visual acuity contrast sensitivity, Beery Visual-Motor Integration (VMI) supplemental tests perception motor coordination, were performed. A short questionnaire was filled in.The...
This Swedish study evaluated whether the severity of retinopathy prematurity (ROP) in extremely preterm infants was related to their overall outcome young adulthood.We followed 39 individuals born between 1988 and 1993 at less than 28 gestational weeks, included Stockholm Neonatal Project. A total 19 were treated for severe ROP, 20 had no or mild ROP. They assessed general cognitive abilities mental health 18 years age compared with 23 term-born controls. Visual acuity examined 21-25 years....
Purpose: To elucidate the association between developmental stage of human figure drawing(HFD) and fine motor control, visual perception, further investigate its potential to be used for screening delay.Methods: Participants were 301 children at 5½ years age, 176 born preterm 125 term, whose HFDs categorized into six stages. Motor-Free-Visual-Perception Test, Movement-ABC, Performance Intelligence Quotient (PIQ: Wechsler Scale), Visual-Motor Integration test used. Fine functions explored...