- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Viral Infections and Immunology Research
- Celiac Disease Research and Management
- Eosinophilic Esophagitis
- Hepatitis Viruses Studies and Epidemiology
- Animal Virus Infections Studies
- Virus-based gene therapy research
Affiliated Hospital of North Sichuan Medical College
2024
Southwest Jiaotong University
2024
Chengdu Third People's Hospital
2024
Eighth Affiliated Hospital of Sun Yat-sen University
2023-2024
Sun Yat-sen University
2023-2024
Observational studies have shown that Helicobacter pylori is related to some otolaryngological diseases. However, it unclear if H. infection causally affects these To elucidate role in 12 common diseases, we conducted two-sample Mendelian randomization analysis.
Norovirus (NV) infection causes acute gastroenteritis in children and adults. Upon with NV, specific CD8+ T cells, which play an important role anti-infective immunity, are activated the host. Owing to NV's wide genotypic variability, it is challenging develop vaccines cross-protective abilities against infection. To aid effective vaccine development, we examined T-cell responses towards viral-structural protein (VP) epitopes, enable binding host susceptibility receptors. We isolated...
Abstract Background Human norovirus (HuNoV) is the leading cause of acute nonbacterial gastroenteritis globally, and its infection usually self-limited, so most people become past Norovirus (NoV)-infected individuals. It known that some antibody responses may play a critical role in preventing viral alleviating disease; however, characteristics functions particular persons with previous infections are not fully understood. Capsid proteins, including VP1 VP2, crucial antigenic components NoV...