- Genetic Neurodegenerative Diseases
- Eosinophilic Esophagitis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Helicobacter pylori-related gastroenterology studies
- Inflammatory Myopathies and Dermatomyositis
- Celiac Disease Research and Management
Chengdu Third People's Hospital
2024-2025
Southwest Jiaotong University
2024-2025
First Affiliated Hospital of Xi'an Jiaotong University
2024
In this study, we conducted a 2-sample Mendelian randomization (MR) analysis to explore the relationship between gastroesophageal reflux disease (GERD) and 16 common otolaryngological diseases. Single-nucleotide polymorphisms that are strongly associated with GERD were used as instrumental variables. The primary estimation of causal effect utilized inverse variance weighting method, supplemented by MR Egger, weighted median, simple mode, mode alternative methods for estimating effect. Then,...
Observational studies have shown that Helicobacter pylori is related to some otolaryngological diseases. However, it unclear if H. infection causally affects these To elucidate role in 12 common diseases, we conducted two-sample Mendelian randomization analysis.