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Research Areas
- Immune Cell Function and Interaction
- CAR-T cell therapy research
- T-cell and B-cell Immunology
Organ transplantation is a lifesaving procedure, with 50,000 transplants happening every year in the United States. However, many patients harbor antibodies and B cells directed against allogeneic human leukocyte antigen (HLA) molecules, notably HLA-A2, greatly decreasing their likelihood of receiving compatible organ. Moreover, antibody-mediated rejection significant contributor to chronic transplant rejection. Current strategies desensitize non- specifically target circulating cells,...
10.1101/2025.03.27.645777
preprint
EN
cc-by-nc-nd
bioRxiv (Cold Spring Harbor Laboratory)
2025-04-01
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