A5016907834- Sexual function and dysfunction studies
- Psychosomatic Disorders and Their Treatments
- Hormonal and reproductive studies
- Urinary Bladder and Prostate Research
- Pain Mechanisms and Treatments
- Tryptophan and brain disorders
- Treatment of Major Depression
- Neuroscience and Neuropharmacology Research
- Obsessive-Compulsive Spectrum Disorders
- Plant Toxicity and Pharmacological Properties
- Pain Management and Placebo Effect
- Nicotinic Acetylcholine Receptors Study
- Connective tissue disorders research
- Amyotrophic Lateral Sclerosis Research
- Alcoholism and Thiamine Deficiency
- Nuclear Receptors and Signaling
- Signaling Pathways in Disease
- Neurotransmitter Receptor Influence on Behavior
- Ion Channels and Receptors
- Cancer, Stress, Anesthesia, and Immune Response
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Plant-based Medicinal Research
- Ferroptosis and cancer prognosis
- Action Observation and Synchronization
- Heat shock proteins research
Southwest Hospital
2025
Army Medical University
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
Chongqing Medical University
2025
University of Copenhagen
2004-2019
Eastern Virginia Medical School
2016
Southern Medical University
2015
Tianjin University
2014
University of Washington
2009-2013
Seattle University
2011
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are the two common neurodegenerative diseases that have been associated with GGGGCC·GGCCCC repeat RNA expansion in a noncoding region of C9orf72. It has previously reported unconventional repeat-associated non-ATG (RAN) translation repeats produces five types dipeptide-repeat proteins (referred to as RAN proteins): poly-glycine-alanine (GA), poly-glycine-proline (GP), poly-glycine-arginine (GR), poly-proline-arginine (PR)...
Electrocoagulation and electroflotation are effective technologies for restaurant wastewater treatment, especially the removal of oil grease. The response surface methodology was used to establish a model treatment using electrocoagulation electroflotation. provides optimum operation conditions. In addition, contributions grease were determined under different conditions an inter-electrode distance 3.6 cm, reaction time 34 min, current density 43 A/m2. efficiency above 95% such When...
The proliferation of all nontransformed adherent cells is dependent upon the development mechanical tension within cell; however, little known about mechanisms by which signals regulated are integrated with those growth factors. We show here that Skp2, a component ubiquitin ligase complex mediates degradation several proteins inhibit proliferation, upregulated when increased develops in intact smooth muscle and its upregulation critical for proliferative response to tension. Notably, whereas...
Saponins form a group of plant-produced glycosides with potential as biopesticide ingredients. The environmental fate saponins has never been fully investigated. In the present study, we use QS-18, specific saponin from Quillaja saponaria an example, to quantify hydrolysis under different conditions pH, temperature and water chemical composition. Saponin in buffer solutions was base-catalyzed followed first-order kinetics. Thus, slow at pH 5.1 half-life 330 ± 220 d (26 °C), which increases...
We investigated the mechanisms of diabetic bladder dysfunction (BD) through analysis roles L- and T-type voltage-gated calcium channels (VGCCs), with ultimate goal identifying potential drug targets for BD.Bladder function db/db (type 2 diabetes) wild type (Wt) mice was evaluated by behavioral tests in vivo cystometry. Contractile responses strips to carbachol were measured or without pre-treatment nifedipine (a L-type VGCC blocker) mibefradil blocker). Furthermore, effects on proliferation...
We performed this study to identify the source of complexes recorded during corpus cavernosum electromyography.A total 10 healthy male volunteers 19 54 years old (mean age 36) with normal erectile function, participated in study. A Porti electrodiagnostic system (TMS International, Enschede, The Netherlands) connected a notebook computer low frequency electromyography via penile surface electrodes 3 phases. In phase 1 baseline was for 30 minutes. 2 skin block followed by minutes recording....
The purpose of this study was to establish a method for monitoring the neural differentiation stem cells using ferritin transgene expression, under control neural-differentiation-inducible promoter, and magnetic resonance imaging (MRI). Human adipose tissue-derived mesenchymal (hADMSCs) were transduced with lentivirus containing human heavy chain 1 (FTH1) gene coupled one three cell-specific promoters: synapsin promoter (SYN1p, neurons), glial fibrillary acidic protein (GFAPp, astrocytes),...
Summary The Shc family of proteins participates in mitogenic and survival signalling through binding to receptor tyrosine kinases. We report here on the expression forebrain, spinal cord hind limb muscles from 30‐month‐old rats with different degrees sensorimotor impairment. ShcA (mRNA protein) is up‐regulated skeletal aged rats, this change relates biological age, i.e. degree behavioural incapacitation, rather than chronological age. Western blot RT‐PCR revealed that increase selectively...
No AccessJournal of UrologyAdult Urology: Sexual Function/Infertility1 Nov 2005CORPUS CAVERNOSUM ELECTROMYOGRAPHY DURING MORNING NAPS IN HEALTHY VOLUNTEERS: FURTHER EVIDENCE THAT CORPUS POTENTIALS REFLECT SYMPATHETICALLY MEDIATED ACTIVITY XIAOGANG JIANG, ERIC J.H. MEULEMAN, HESSEL WIJKSTRA, and GORM WAGNER JIANGXIAOGANG JIANG , MEULEMANERIC MEULEMAN WIJKSTRAHESSEL WIJKSTRA WAGNERGORM View All Author Informationhttps://doi.org/10.1097/01.ju.0000176748.66044.a2AboutFull TextPDF ToolsAdd to...
Study Type – Aetiology (case control) Level of Evidence 3b What's known on the subject? and What does study add? As one major components extracellular matrix, elastic fibres are believed to enhance tissue compliance. However, role in normal bladder function dysfunction remains speculative. Although transgenic mice overexpressing elastin showed increased compliance, findings patients with non‐compliant bladders inconsistent. Using elastin‐deficient mouse models, this provides first direct...
This work comprises, the feasibility of anaerobic co-digestion waste activated sludge and corn straw to produce methane.It showed that could increase C/N substrate it was benefit for digestion.Anaerobic efficiency higher than digestion pure sludge.It found raise biogas yield initial production time 3-6 days before sludge.Biogas lasted 27 cumulative 7 times sludge.
To study the effects of ketamine and alcohol on learning memory in mice its possible mechanism.Forty were divided into 4 groups: normal control group, plus group. Ketamine given by intraperitoneal injection intragastric administration, respectively, 1 time per day, for 14 days. The ability was tested method step-down Morris water maze. Acetylcholine (ACh) 5-hydroxy tryptamine(5-HT) brain tissue analyzed mechanism.(1) Step-down: treatment groups lessened latency added wrong times (P < 0.05)....