A5004475174- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Curcumin's Biomedical Applications
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Microbial Natural Products and Biosynthesis
- Microencapsulation and Drying Processes
- Pharmacological Effects of Natural Compounds
- Diabetes Management and Research
- Pharmaceutical studies and practices
- Analytical Methods in Pharmaceuticals
- Analytical Chemistry and Chromatography
- Proteins in Food Systems
- Natural product bioactivities and synthesis
- Marine Sponges and Natural Products
- Polysaccharides Composition and Applications
- RNA Interference and Gene Delivery
- Hydrogels: synthesis, properties, applications
- Boron and Carbon Nanomaterials Research
- Crystallization and Solubility Studies
- Food Chemistry and Fat Analysis
- Biochemical effects in animals
- Biochemical Analysis and Sensing Techniques
- Probiotics and Fermented Foods
- Phytochemistry and biological activity of medicinal plants
Hebei University
2014-2023
Baoding University
2021
GD Goenka University
2021
Affiliated Hospital of Hebei University
2019
Jiangsu Hengrui Medicine (China)
2009
A new microemulsions system of curcumin (CUR-MEs) was successfully developed to improve the solubility and bioavailability curcumin. Several formulations were prepared evaluated using different ratios oils, surfactants, co-surfactants (S&CoS). The optimal formulation, which consists Capryol 90 (oil), Cremophor RH40 (surfactant), Transcutol P aqueous solution (co-surfactant), could enhance up 32.5 mg/mL. pharmacokinetic study performed in rats compared corresponding suspension. stability...
A novel chemical hydrogel was facilely achieved by coupling 1,4-phenylenebisdiboronic acid modified halloysite nanotubes (HNTs-BO) with compressible starch. The (HNTs) and prepared were characterized solid-state nuclear magnetic resonance (NMR), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission microscope (TEM). linkage of B-C in the can be degraded into B-OH C-OH units presence H2O2 result degradation hydrogel. Pentoxifylline loaded lumen...
This paper focused on formulating high-performance curcumin spray-dried powders for inhalation (curcumin-DPIs) to achieve a high lung concentration. Curcumin-DPIs were produced using wet milling combined with the spray drying method. The effects of different times particle size and aerodynamic performance investigated. curcumin-DPIs characterized by scanning electron microscopy (SEM), differential calorimetry (DSC), powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy...
A systematic chemical exploration of the marine-derived fungus Penicillium janthinellum led to isolation four indole-diterpenoid derivatives (1-4), including new penijanthines C and D (1 2), a pair steroidal epimers, penijanthoids B (5 6). The calculated ECD spectra Snatzke's method for compound 1 were carried out determine its absolute configuration. configuration 3 was established by X-ray diffraction methods first time. DP4plus approach used elucidate configurations C-25 epimeric steroids...
The purpose of the current study was to improve solubility ibuprofen, a poorly water-soluble drug, in microemulsion system that is suitable for oral administration. Microemulsion prepared using different sorts oils, surfactants, and co-surfactants. Pseudo-ternary phase diagrams were used evaluate domain. formulations characterized by drug vehicle, droplet size, release. optimal formulation consists 17% Labrafil M 1944CS, 28% Cremophor RH40/Transcutol P (3:1, w/w), 55% water, with maximum...
Abstract Determination of the absolute configrations for natural products is one most important and challenging tasks, especially when molecules display high conformational flexibility. In this paper, eight new prenylxanthones, aspergixanthones A-H ( 1 – 8 ), known analogue 9 were isolated from marine-derived fungus Aspergillus sp. ZA-01. The configurations C-14 C-15 in difficult to be assigned due flexibility chains. To solve problem, experimental ECD, ORD, VCD spectra combined analysis...