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Marina Delgobo

ORCID: 0000-0002-9456-9913
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About
Contact & Profiles
A5053415034
Research Areas
  • Glutathione Transferases and Polymorphisms
  • Genomics, phytochemicals, and oxidative stress
  • Redox biology and oxidative stress
  • Nitric Oxide and Endothelin Effects
  • Pain Mechanisms and Treatments
  • Magnolia and Illicium research
  • Signaling Pathways in Disease
  • Histone Deacetylase Inhibitors Research
  • Eicosanoids and Hypertension Pharmacology
  • Biochemical Acid Research Studies
  • Inflammatory mediators and NSAID effects
  • Machine Learning in Materials Science
  • Estrogen and related hormone effects
  • Autophagy in Disease and Therapy
  • Endometriosis Research and Treatment
  • Computational Drug Discovery Methods
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Cancer Treatment and Pharmacology
  • Glioma Diagnosis and Treatment
  • Cancer Risks and Factors
  • Reproductive System and Pregnancy

Universidade Federal de Santa Catarina
 2019-2024

 Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer
OPENALEX - Publications 
Marina Delgobo Rosângela Mayer Gonçalves Marco Antônio Delazeri Marcelo Falchetti Alessandro Zandoná and 12 more Raquel Nascimento das Neves Karoline Almeida Adriane Cristina Fagundes Daniel Pens Gelain João Isidro Fracasso Guilherme Baroni de Macêdo Leonardo Priori Nicklas Bassani Alexander J. R. Bishop Cassiano Mateus Forcelini José Cláudio Fonseca Moreira Alfeu Zanotto‐Filho

10.1016/j.freeradbiomed.2021.10.020 article EN Free Radical Biology and Medicine 2021-10-20
 N-acetylcysteine and alpha-lipoic acid improve antioxidant defenses and decrease oxidative stress, inflammation and serum lipid levels in ovariectomized rats via estrogen-independent mechanisms
OPENALEX - Publications 
Marina Delgobo Jonathan Paulo Agnes Rosângela Mayer Gonçalves Vitória Wibbelt dos Santos Eduardo Benedetti Parisotto and 2 more Ariane Zamoner Alfeu Zanotto‐Filho

10.1016/j.jnutbio.2019.02.012 article EN The Journal of Nutritional Biochemistry 2019-03-10
 Late autophagy inhibitor chloroquine improves efficacy of the histone deacetylase inhibitor SAHA and temozolomide in gliomas
OPENALEX - Publications 
Rosângela Mayer Gonçalves Jonathan Paulo Agnes Marina Delgobo Priscila Oliveira de Souza Marcos Paulo Machado Thomé and 4 more Luana Heimfarth Guido Lenz José Cláudio Fonseca Moreira Alfeu Zanotto‐Filho

Glioblastoma multiforme is the most aggressive type of primary brain tumor associated with few therapeutic opportunities and poor prognosis. In this study, we evaluated efficacy combining temozolomide (TMZ) suberoylanilide hydroxamic acid (SAHA) - a specific histone deacetylases inhibitor in glioma models vitro vivo. cell lines, combined TMZ/SAHA promoted more cytotoxicity, G2/M arrest apoptosis than either drugs alone. was detected as soon 24 h post drug exposure preceded apoptosis, which...

10.1016/j.bcp.2019.03.015 article EN publisher-specific-oa Biochemical Pharmacology 2019-03-13
 Antioxidants Improve Oxaliplatin-Induced Peripheral Neuropathy in Tumor-Bearing Mice Model: Role of Spinal Cord Oxidative Stress and Inflammation
OPENALEX - Publications 
Jonathan Paulo Agnes Vitória Wibbelt dos Santos Raquel Nascimento das Neves Rosângela Mayer Gonçalves Marina Delgobo and 11 more Carolina Saibro Girardi Débora Denardin Lückemeyer Marcella de Amorim Ferreira Sérgio José Macedo-Júnior Samantha Cristiane Lopes Fernando Spiller Daniel Pens Gelain José Cláudio Fonseca Moreira Rui Daniel Prediger Juliano Ferreira Alfeu Zanotto‐Filho

10.1016/j.jpain.2021.03.142 article EN publisher-specific-oa Journal of Pain 2021-03-24
 COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice
OPENALEX - Publications 
Rosângela Mayer Gonçalves Marina Delgobo Jonathan Paulo Agnes Raquel Nascimento das Neves Marcelo Falchetti and 13 more T.S. Casagrande Ana Paula Vargas Garcia Thaynan Cunha Vieira Nauana Somensi Maciel Alencar Bruxel Daniel Augusto Gasparin Bueno Mendes Alex Rafacho André Báfica Daniel Pens Gelain José Cláudio Fonseca Moreira Geovanni Dantas Cassali Alexander J. R. Bishop Alfeu Zanotto‐Filho

10.1016/j.canlet.2021.01.003 article EN publisher-specific-oa Cancer Letters 2021-01-11
 Omics-based identification of an NRF2-related auranofin resistance signature in cancer: Insights into drug repurposing
OPENALEX - Publications 
Marcelo Falchetti Marina Delgobo Helena Zancanaro Karoline Almeida Raquel Nascimento das Neves and 5 more Bárbara dos Santos Natália Marcéli Stefanes Alexander J. R. Bishop Maria Cláudia Santos‐Silva Alfeu Zanotto‐Filho

10.1016/j.compbiomed.2022.106347 article EN Computers in Biology and Medicine 2022-11-25
 Efficient identification of novel anti-glioma lead compounds by machine learning models
OPENALEX - Publications 
Bruno J. Neves Jonathan Paulo Agnes Marcelo do Nascimento Gomes Marcio Roberto Henriques Donza Rosângela Mayer Gonçalves and 7 more Marina Delgobo Lauro Ribeiro de Souza Neto Mário Roberto Senger Floriano Paes Silva Sabrina Baptista Ferreira Alfeu Zanotto‐Filho Carolina Horta Andrade

10.1016/j.ejmech.2019.111981 article EN European Journal of Medicinal Chemistry 2019-12-19
 S-Denitrosylation counteracts local inflammation and improves survival in mice infected with K. pneumoniae
OPENALEX - Publications 
Filipe Rodolfo Moreira Borges Oliveira Thiele Osvaldt Rosales Daiane Mara Bobermin Marina Delgobo Alfeu Zanotto‐Filho and 2 more Regina Sordi Jamil Assreuy

10.1016/j.niox.2024.12.001 article EN Nitric Oxide 2024-12-07
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