A5077705802- Insect and Pesticide Research
- X-ray Diffraction in Crystallography
- Mosquito-borne diseases and control
- Crystallization and Solubility Studies
- Insect Pest Control Strategies
- Essential Oils and Antimicrobial Activity
- Dermatological diseases and infestations
- Dengue and Mosquito Control Research
- Crystallography and molecular interactions
- Burn Injury Management and Outcomes
- Phytochemistry and Biological Activities
- Advanced Drug Delivery Systems
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Insect Utilization and Effects
- Microencapsulation and Drying Processes
- Biochemical Analysis and Sensing Techniques
- Dermatology and Skin Diseases
- Neurological disorders and treatments
- Ion Channels and Receptors
- Mycotoxins in Agriculture and Food
- Advancements in Transdermal Drug Delivery
- Parkinson's Disease Mechanisms and Treatments
- Drug-Induced Hepatotoxicity and Protection
- Vitamin C and Antioxidants Research
- Genomics, phytochemicals, and oxidative stress
Defence Research Laboratory
2012-2025
University of Delhi
2024
Gujarat Matikam Kalakari & Rural Technology Institute
2020
Pharmaceutical Biotechnology (Czechia)
2013
Polymeric biomaterials are in extensive use the domain of tissue engineering and regenerative medicine. High performance hyperbranched epoxy is projected here as a potential biomaterial for regeneration. Thermosetting nanocomposites were prepared with Homalomena aromatica rhizome oil-modified bentonite well organically modified montmorillonite clay. Fourier transformed infrared spectroscopy, x-ray diffraction scanning transmission electron microscopic techniques confirmed strong interfacial...
Lung fibrosis (LF) is a serious complication with very limited therapeutic options. This study aimed to find potential compound for targeting LF and develop chitosome formulation minimize any inherent drawbacks of the achieve effective drug delivery. In total, 79 natural compounds were screened using an in silico approach against five targeted proteins (3HMG, 6B8Y, 2FAP, 3CQU, 3DK9). Amongst these, quercetin (QER) exhibited best efficacy (-14.725 kcal mol-1) ΔG average (-86.45 ± 6.24) mol-1...
Personal protection measures using insecticide-treated fabric is one of the most effective strategies to prevent bites hematophagous insects. Many countries have had success treating fabrics with pyrethroids on an individual level.In current study, a new combination insecticides, alpha-cypermethrin (ACP) and deltamethrin (DET), has been impregnated composed 50:50 blend polyester cotton. Residual morphological analysis was performed along evaluation physical parameters. Biological evaluations...
Summary Six essential oils viz. Eucalyptus citriodora , Cymbopogon citratus Callistemon lanceolatus Cinnamomum camphora Citrus limon Tagetes petula as well two standard antibiotics, miconazole and clotrimazole, were tested in vitro for their anticandidial activity. All these exhibited higher activity than the synthetic antibiotics. Highest zone of inhibition was recorded E. (8.50 mm μ l −1 ) followed by C. (5.63 establishing promising potential.
Health hazards of titanium dioxide nanoparticles (TiO2-NPs) have raised severe concerns because the paucity information regarding toxic effects among population. In present research, in vitro and vivo cytotoxic potential TiO2-NPs were evaluated using flow cytometric techniques. Further, genotoxic endpoints estimated by means comet, micronucleus (MN), chromosomal aberration (CA) assays. analysis was performed at concentration range 10-100 µg/mL murine RAW 264.7 cells. experiments conducted on...
Vector-borne diseases impose enormous menace worldwide including India. The principal strategies for combating are vector control the use of ovicide and larvicide against mosquitoes. present study assessed role larvicidal ovicidal properties dried leaf extract Piper longum also determined their toxicity three important 3rd instar mosquito larvae, viz., Aedes aegypti, Anopheles stephensi Culex quinquefasciatus. plant extracts with different concentrations caused a significant mortality as...
Vitex negundo L. (Verbenaceae) is a hardy plant widely distributed in the Indian subcontinent and used for treatment of wide spectrum health disorders traditional folk medicine, some which have been experimentally validated. In present study, we aimed to investigate anti-inflammatory effects V. carrageenan-induced paw edema rats, probable mechanism action.Paw was produced by injecting 1% solution carrageenan, volume measured before after carrageenan injection up 5 h. leaf oil extracted using...
Mycotoxins are fungal toxin and contaminated to human through food-stuffs. Hematological abnormality, mainly thrombocytopenia leukopenia induced after consumption of mycotoxin. Experiments were conducted evaluate the hematotoxicity trichothecenes mycotoxins in Sprague-Dawley rats. parameters viz. Hemoglobin, hematocrit, erythrocyte count (RBC), white blood cell (WBC), lymphocytes, monocytes, neutrophils, eosinophils, basophils, mean corpuscular volume, hemoglobin, hemoglobin concentration,...
Numerous adverse effects on human health have been reported in epidemiological studies of oleoresin capsicum (OC) and other riot control agents (RCAs). Importantly, the daunting risk such RCAs can be neutralized by optimizing desired concentration for mob dispersal. Hence, a nonlethal combinational formulation (NCF) was prepared dispersing rioters without imparting fatal outcomes. However, utilization NCF, it is essential to recognize its extent potential toxicity. Therefore, current...
Vitex negundo is a common herb in different herbal formulation. The potential acute and sub-chronic dermal toxicities were evaluated as per OECD (Organization for Economic Cooperation Development) guidelines 402 411, respectively. Both sexes of Wistar rats exposed to oil 2000 mg/kg body weight toxicity, whereas the toxicity study, 250, 500 1000 weight, respectively, five times week 90 d. In studies, all animals normal without any behavioral, serum biochemistry, hematology, necroscopical...
Objective: Melatonin and pumpkin seed oil, along with US FDA approved UV filters were incorporated into a formulation for enhancement of protection by exerting an antioxidant effect. The objective this study was to assess the protective effect against ultraviolet (UV) radiation-induced photo dermatitis in rats, which is established model aetiopathogenic mechanisms psoriasis vulgaris, as former exhibits same features those clinical vulgaris humans.Materials methods: animals segregated five...
Defense personnel utilize capsaicin-based ocular sprays as non-lethal agents for law implementation during instances of mob violence. This study involves the capsaicin antagonist Capsazepine and investigation whether Capsazepine's antagonistic approach can be favorably utilized defense utilization to block capsaicin-initiated pain inflammation via pathway.Ocular capsazepine in situ gels were prepared with polymers Pluronic F-127 Chitosan; optimized formulation was quantified tissues...
Abstract Mast cell activation is initiated by two signalling pathways: immunoglobulin E (IgE)‐dependent and IgE‐independent pathway. It reported that the type or pseudo‐allergy pathway gets activated G‐protein‐dependent of mast cell. Recently, adiponectin (APN) receptors, AdipoR1, AdipoR2 have been identified as G‐protein‐coupled receptors (GPCRs). Interestingly, APN replenishment to activate Nrf2/HO‐1 axis. However, no study has performed interlinking role axis in pseudo‐allergic reaction....
Frostbite is a cold induced injury which occurs due to exposure of particular site body sub-zero temperature. One the primary reasons for lack proper studies about underlying mechanism frostbite non-availability any reliable animal model and method inflicting frostbite. In our current research, device was designed standardised inflict wound in wistar rat. A formulation comprising different combination essential oils also developed its activity assessed found effective treatment wound.
<title>Abstract</title> Emerging infestations of bed bugs are affecting normal human lifestyles globally. To perform a scientific experiment, there is paramount requirement for an established rearing condition. Thus, this study has been conducted to optimize and establish the conditions bud (<italic>Cimex lectularius</italic> L.) based upon temperature relative humidity. The have projected onto three temperatures (20 ºC, 25 30 ºC) humidity (50%, 70%, 90%) check their overall growth survival...
Abstract Emerging infestations of bed bugs are affecting normal human lifestyle globally. This study has been designed to optimize the rearing conditions for Cimex lectularius L. (Hemiptera), support scientific research on them. Bed have projected onto three different temperature (20 °C, 25 and 30 °C) relative humidity (50%, 70%, 90%) check their overall growth survival rate. Adult mortality, weight loss, egg laying, percentage hatching, hatching initiation completion, nymph molting...