A5051742241- Berberine and alkaloids research
- Drug-Induced Hepatotoxicity and Protection
- Liver Disease and Transplantation
- Advances in Cucurbitaceae Research
- Microtubule and mitosis dynamics
- Nigella sativa pharmacological applications
- Calcium signaling and nucleotide metabolism
- Andrographolide Research and Applications
- Skin Protection and Aging
- Liver Disease Diagnosis and Treatment
- Inflammatory mediators and NSAID effects
- Alkaloids: synthesis and pharmacology
- Cancer, Lipids, and Metabolism
- Cancer Cells and Metastasis
- Seaweed-derived Bioactive Compounds
- Cancer-related Molecular Pathways
- Diet, Metabolism, and Disease
- Eicosanoids and Hypertension Pharmacology
- Chemotherapy-induced organ toxicity mitigation
- Natural Antidiabetic Agents Studies
- Collagen: Extraction and Characterization
- Bioactive natural compounds
- Plant Pathogenic Bacteria Studies
- Renal Transplantation Outcomes and Treatments
Alexandria University
2025
Benha University
2016
City of Scientific Research and Technological Applications
2013-2015
Abstract Background Berberis vulgaris is a well known plant with traditional herbal medical history. The aims of this study was to bioscreen and compare the in vitro biological activity (antioxidant, cholinergic, antidaibetic anticancer) barberry crude extract berberine active compound. Methods effect B. chloride on cellular thiobarbituric acid reactive species (TBARS) formation, diphenyle–α-picrylhydrazyl (DPPH) oxidation, nitric oxide (NO) radical scavenging capability, superoxide...
Berberine is a plant alkaloid that has several pharmacological effects such as antioxidant, antilipidemic, and anti-inflammatory effects. Nonalcoholic steatohepatitis (NASH) triggers different aspects of disorders impaired endogenous lipid metabolism, hypercholesterolemia, oxidative stress, neurotoxicity. In this study, we examined the mechanism by which NASH induces neurotoxicity protective effect berberine against both its associated induced rats showed significant impairments in...
Berberis vulgaris is a shrub in the family Berberidaceae. B. as well other berberine (BER) containing plants are used medicinally virtually all-traditional medical systems. In present study, efficacy of ethanolic extract dried root powder anti bacterial, fungal and hepatitis C was evaluated. Also, its for induction phagocytisis lymphoporiferation determined. The data showed that have strong bacterial effect (gram positive gram negative) at concentrations range from 2.5 to 20 mg/ml. Anti...
Liver cancer, predominantly hepatocellular carcinoma (HCC), represents a complex and fatal malignancy driven primarily by oxidative stress inflammation.The chemopreventive effect of omega-3 on inflammatory markers damage, caspase-3, antioxidant status histopathological alterations in hepatic tissue N-nitrosodiethylamine (DEN)-induced HCC male rats was investigated.To induce HCC, were given DEN (200 mg/kg b.wt.,i.p) three times at 15 day interval.75 divided into five equal groups.Control...
Cyclosporine A (CsA) is a strong immunosuppressive drug, but its use frequently accompanied by severe renal toxicity. The potential renoprotective effect of Thymoquinone (TQ) against CsA-induced nephrotoxicity in rats was assessed. Thirty adult white male albino were divided into three equal groups. Group I: (Normal control), received no drugs, II: (CsA treated), oral dose (25 mg/kg b.wt/day) for 21 days. III: (TQ protected + CsA), (10 orally 7 days before and during CsA treatment. obtained...
Cyclosporine A (CsA) is a drug used as immunosuppressive agent in organ transplant and non-transplant medicine. The main secondary effect results from CsA treatment nephrotoxicity. protective of Grape seed proanthocyanidin extract (GSPE) against CsA-induced nephrotoxicty rats was assessed. Thirty male were divided into three equal groups. Group I: (Normal control), received no drugs, II: (CsA treated), oral dose (25 mg/kg b.wt/day) for 21 successive days. III: (GSPE protected+ CsA), GSPE...