A5081078857- Crystallization and Solubility Studies
- Metal complexes synthesis and properties
- X-ray Diffraction in Crystallography
- Metal-Catalyzed Oxygenation Mechanisms
- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- Protein Interaction Studies and Fluorescence Analysis
- Crystallography and molecular interactions
- Mycotoxins in Agriculture and Food
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Biofuel production and bioconversion
- Covalent Organic Framework Applications
- Photochemistry and Electron Transfer Studies
- Nanoparticle-Based Drug Delivery
- Bioactive Compounds and Antitumor Agents
- Chemical Synthesis and Characterization
- Enzyme Production and Characterization
- Supramolecular Self-Assembly in Materials
- Berberine and alkaloids research
- Analytical Chemistry and Chromatography
- Antifungal resistance and susceptibility
- Cancer therapeutics and mechanisms
- Animal testing and alternatives
- Synthesis and Biological Evaluation
University of Iowa
2025
Madurai Kamaraj University
2023
Anna University, Chennai
2020-2023
Bharathidasan University
1991-2017
Abstract A novel trinuclear zinc(II) complex [Zn 3 L 2 (μ‐O CCH ) (CH OH) 4 ] ( 1 that contains an N,O‐donor Schiff base ligand {H = 2‐[(2‐hydroxyphenylimino)methyl]‐6‐methoxyphenol} has been synthesized and crystallographically characterized. The X‐ray crystal structure of three centers, which have distorted‐octahedral coordination geometry, the molecule crystallizes in Pbcn space group. displays significant catecholase oxidation activity methanolic medium through a ligand‐centered radical...
Gliotoxin (GT) and fumagillin (FUM) are mycotoxins most abundantly produced by Aspergillus fumigatus during the early stages of infection to cause invasive aspergillosis (IA). Therefore, we hypothesized that GT FUM could be possible source virulence factors, which put test adopting in vitro monoculture novel integrated multiple organ co-culture (IdMOC) A549 L132 cell. We found (i) is more cytotoxic lung epithelial cells than FUM, (ii) act synergistically inflict pathology Reactive oxygen...
A simple and cost-effective synthesis method for zeolitic imidazolate framework-8 (ZIF-8) was developed loaded with metformin (MET@ZIF-8) pH sensitive-release behaviour the treatment of lung cancer. ZIF-8 MET@ZIF-8 were subjected to particle size, zeta potential analysis HR-TEM through which it shows evidence that particles had spherical morphology nanosize. Percentage (MET) loading in found be 63.39 ± 1.32%. Dissociation into its coordination ions at acidic conditions (pH 5–6) thereby leads...
The X-ray diffraction and spectroscopic properties of 1-amino-4-hydroxy-9,10-anthraquinone (1-AHAQ), a simple analogue anthracycline chemotherapeutic drugs were studied by adopting experimental computational methods. optimized geometrical parameters obtained from methods compared with the results analysis two found to be in reasonably good agreement. study, Density Functional Theory (DFT) natural bond orbital (NBO) indicated types hydrogen bonds molecule. IR spectra 1-AHAQ Vibrational Energy...
Structural, spectroscopic and biochemical studies on 2-amino-3-hydroxy-anthraquinone (AQ) were carried out.
Tephrosia purpurea is an Indian herb used in traditional medicine to treat various diseases such as jaundice, asthma, liver and urinary disorders. However, the anti-cancer potential of T. on hepatocellular carcinoma (HCC) poorly understood. Therefore, this study aims investigate activity HepG2 cells.The leaves root were extracted with methanol using soxhlet apparatus. The cytotoxicity extracts cells was evaluated MTT assay whereas mode cell death examined by AOEB, Hoechst JC1 staining under...
The interactions of copper complex (CuQ2) 1-amino-4-hydroxy-9,10-anthraquinone (QH) with calf thymus DNA, anionic surfactant sodium dodecyl sulfate (SDS), and cationic cetyltrimethylammonium bromide (CTAB) were investigated in an aqueous solution at physiological pH (7.4). Affinities such molecule to DNA micelles, a model for biological membrane, are important determining its action. Using different models, various binding parameters evaluated both molecule–DNA interaction...
The rise in accumulation of agricultural wastes has demanded ways effectively utilising this waste and converting them into useful products. A large portion the comprises lignocellulose. Lignocellulose, being most abundant carbon source available, can be used as a substrate to convert products like lactic acid ethanol. However, lignocellulose bio-conversion comes with its own challenges, mainly due complex structure. There are several parameters affecting efficiency bioconversion acid. This...