A5101946903- Genetic Associations and Epidemiology
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- Functional Brain Connectivity Studies
- Central Venous Catheters and Hemodialysis
- Chromosomal and Genetic Variations
- Advanced Neuroimaging Techniques and Applications
- RNA modifications and cancer
- Rock Mechanics and Modeling
- Intravenous Infusion Technology and Safety
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Glaucoma and retinal disorders
- Genomic variations and chromosomal abnormalities
- Neural dynamics and brain function
- Gastric Cancer Management and Outcomes
- Tunneling and Rock Mechanics
- Diagnosis and Treatment of Venous Diseases
- Radioactivity and Radon Measurements
- Livestock and Poultry Management
- Galectins and Cancer Biology
- Retinal Imaging and Analysis
- Spinal Hematomas and Complications
- Optical Imaging and Spectroscopy Techniques
- Neurosurgical Procedures and Complications
Jiangxi Provincial People's Hospital
2024-2025
First Affiliated Hospital of Jiangxi Medical College
2024-2025
Zhejiang University
2017-2024
Henan Polytechnic University
2024
Qinghai University Affiliated Hospital
2022-2024
Hangzhou Medical College
2023
Zhejiang Provincial People's Hospital
2023
Institute of Bioinformatics
2023
Nanjing University
2023
Air Force General Hospital PLA
2021
GPCR 37 (GPR37) is a expressed in the CNS; its physiological and pathophysiological functions are largely unknown. We tested role of GPR37 ischemic brain knockout (KO) mice, exploring idea that might be protective against damage. In an stroke model, KO mice exhibited increased infarction cell death compared with wild-type (WT) measured by 2,3,5-triphenyl-2H-tetrazolium chloride TUNEL staining 24 h after stroke. Moreover, more severe functional deficits were detected adhesive-removal corner...
In this study, we proposed an efficient algorithm (X-LD) for estimating linkage disequilibrium (LD) patterns a genomic grid, which can be of inter-chromosomal scale or small segments. Compared with conventional methods, the method was significantly faster, dropped from O(nm2) to O(n2m)-n sample size and m number SNPs, consequently were permitted explore in depth unknown reveal long-anticipated LD features human genome. Having applied 1000 Genome Project (1KG), found (1) extended LD, driven...
Abstract Kinase fusions represent an important type of somatic alterations that promote oncogenesis and serve as diagnostic markers in lung cancer. We aimed to identify the landscape clinically relevant kinase Chinese cancer explore rare rearrangements; thus, providing valuable evidence for therapeutic decision making. performed genomic profiling 425 cancer-relevant genes from tumor/plasma biopsies a total 17,442 patients using next generation sequencing (NGS). Patients’ clinical...
Cancer indeed represents a significant public health challenge, and unplanned extubation of peripherally inserted central catheter (PICC-UE) is critical concern in patient safety. Identifying independent risk factors implementing high-quality assessment tools for early detection high-risk populations can play crucial role reducing the incidence PICC-UE among patients with cancer. Precise prevention treatment strategies are essential to improve outcomes safety clinical settings.This study...
Abstract Having an accurate understanding of the scale effect surface morphology characteristics is crucial to examining mechanical behavior rock structural plane. At present, quantification and sampling methods show diversity, which potential reason for inconsistent research conclusions on effect. Firstly, based mathematical statistics correlation analysis, most representative parameter proposed from hundreds morphological parameters. Then, previous are analyzed. In order ensure that...
Co-occurrence of pyrethroids and metals in watersheds previously has been reported to pose great risk aquatic species. Pyrethroids are a class chiral insecticides that have shown enantioselective toxicity biotransformation. However, the influence on enantioselectivity not yet evaluated. In present study, effects cadmium (Cd), copper (Cu), lead (Pb) metabolism cis-bifenthrin (cis-BF) were investigated zebrafish at environmentally relevant concentrations. The addition Cd, Cu, or Pb...
We previously reported that Hook1 inhibits the phosphatase activity of SHP2 in regulation epithelial-mesenchymal transition (EMT) lung cancer. In this study, we performed a comprehensive analysis and expression relationships with prognosis patients non-small cell cancer (NSCLC).A total 121 NSCLC were included study. Expression was assessed by immunohistochemistry Western blot analysis. The overall survival rate analysed using Cox's ratio hazard multivariate log-rank test.In tumour tissue...
Objective: Primary angle-closure glaucoma (PACG) is a globally prevalent, irreversible eye disease leading to blindness.Previous neuroimaging studies demonstrated that PACG patients were associated with gray matter function changes.However, whether the white matter(WM) changes in remains unknown.The purpose of study investigate WM patients.Methods: In total, 40 and well-matched HCs participated our underwent resting-state functional magnetic resonance imaging (rs-fMRI) scans.We compared...
<sec> <title>BACKGROUND</title> Central venous access devices (CVADs) play a crucial role in providing treatment and supportive care for cancer patients. However, catheter-related thrombosis (CRT) poses significant risk to patient safety., which will interrupt treatment, delay the patient's therapeutic period, prolong hospitalization, increase patient’s physical, mental, economic burden. Identifying independent factors CRT patients, proactively utilizing high-quality assessment tools...
Background Thyroid-associated ophthalmopathy (TAO) is a prevalent autoimmune disease characterized by ocular symptoms like eyelid retraction and exophthalmos. Prior neuroimaging studies have revealed structural functional brain abnormalities in TAO patients, along with central nervous system such as cognitive deficits. Nonetheless, the changes static dynamic network connectivity of patients are currently unknown. This study delved into modifications (sFNC) (dFNC) among thyroid-associated...
Mounting neuroimaging evidence indicates that patients with thyroid-associated ophthalmopathy (TAO) demonstrate altered brain function and structure. Nonetheless, the alterations in topological properties of functional connectome TAO are not yet fully understood. This study aimed to investigate organization using graph-theoretic methods. Twenty-five (10 males 15 females) 25 age-, sex-, education-matched healthy controls (HCs) (the HC data from same dataset previous studies) underwent...
Objective An increasing amount of neuroimaging evidence indicates that patients with anterior segment ischemic optic neuropathy (AION) exhibit abnormal brain function and structural architecture. Some studies have shown there are functional changes in the visual area AION patients. Nevertheless, alterations topological properties connectivity among remain unclear. This study aimed to investigate organization a group using graph theory methods. Methods Resting-state magnetic resonance imaging...
In this study, we proposed an efficient algorithm (X-LD) for estimating LD patterns a genomic grid, which can be of inter-chromosomal scale or pair small segments. Compared with conventional methods, the method was significantly faster, and consequently were permitted to explore in depth unknown reveal long-anticipated features human genome. Having applied as demonstrated 1000 Genome Project (1KG), found: I ) The extended LD, driven by population structure, universally existed, strength...
radical surgery for elderly patients and are beneficial of clinical application.
Plexiform fibromyxoma (PF), known as plexiform angiomyxoid myofibroblastic tumor firstly, is derived from gastrointestinal mesenchyme cells, being officially adopted a distinct benign entity in the 2010 WHO Classification of Tumors Digestive System. We report case 32-year-old Chinese man who presented with slight intermittent acid regurgitation and abdominal discomfort. Endoscopy imaging studies revealed muscularis mucosa mass gastric antrum initial suspicion GIST. Microscopically, spindle...
Objective To study the clinical issues of progressive epidural hematoma (PEDH).Method The incidence,impacts on course and short - term outcomes predictors PEDH were retrospectively studied.Results occurred in 20.3％ patients.The rates neurological deterioration surgical treatment due to patients with significantly higher than those without PEDH.There was not a difference outcome between timing from injury first CT scanning,volume CT,rate other intracranial injuries,hypocoagulability heavy...
<sec> <title>BACKGROUND</title> Cancer indeed represents a significant public health challenge, and unplanned extubation of peripherally inserted central catheter (PICC-UE) is critical concern in patient safety. Identifying independent risk factors implementing high-quality assessment tools for early detection high-risk populations can play crucial role reducing the incidence PICC-UE among patients with cancer. Precise prevention treatment strategies are essential to improve outcomes safety...
Abstract In this study, we proposed an efficient algorithm (X-LD) for estimating LD patterns a genomic grid, which can be of inter-chromosomal scale or small segments. Compared with conventional methods, the method was significantly faster, dropped from 𝒪 ( nm 2 ) to n m )— sample size and number SNPs, consequently were permitted explore in depth unknown reveal long-anticipated features human genome. Having applied 1000 Genome Project (1KG), found: I The extended LD, driven by population...