The objectives of this study were to determine if clinical trials in breast cancer, with an investigational drug, created direct drug cost savings for the healthcare system related avoidance best standard care treatments used these studies. aim was quantify potential avoidance.We conducted a retrospective observational during period (2014-2016). We included managed by pharmacy department and provided sponsor. patients had therapeutic alternative defined as treatment that should have been...

<h3>Background and Importance</h3> Our country's legislation bans the return of dispensed drugs to Pharmacy Services, potentially leading increased costs for National Health System. <h3>Aim Objectives</h3> To estimate cost pill wastage due dose modifications discontinuation oral anticancer drugs. <h3>Material Methods</h3> Retrospective economic evaluation carried out in an intermediate complexity hospital. Using electronic medical record, dispensations between July 2022 2023 were identified....

<h3>Background and Importance</h3> Multiple myeloma (MM) is an incurable chronic disease, so the quality of life (QoL) patients with MM important criterion to consider. The patient-reported outcomes (PROs) are a fundamental tool know success treatment in clinical practice. <h3>Aim Objectives</h3> Assessing QoL as PROs adult treated daratumumab. <h3>Material Methods</h3> Retrospective observational study which included daratumumab between 01/2019 04/2023 second-level Hospital. electronic...

<h3>Background and importance</h3> Tofacitinib baricitinib were recently approved for rheumatoid arthritis (RA) treatment. This was a breakthrough because of their oral administration new mechanism action. <h3>Aim objectives</h3> To analyse tofacitinib treatment RA adverse effects (AE) after starting in second level hospital. <h3>Material methods</h3> A retrospective observational study conducted all patients until September 2019. The collected variables sex, age, previous disease modifying...

<h3>Background</h3> The treatment of rare autoimmune diseases presents for patients the additional problem limited therapeutic options, which are usually reduced to corticosteroids and immunosuppressants. use rituximab could be an effective alternative. <h3>Purpose</h3> To determine efficacy with in diseases. <h3>Material methods</h3> Retrospective observational study who were treated between January 2008–March 2014. Data was collected from electronic prescription records. Diagnosis, reason...

<h3>Background</h3> Mucositis is one of the most frequent complications in patients receiving chemotherapy. Currently there no standard treatment, and its management essentially based on adequate oral hygiene mouthwashes. In our hospital, pharmacy department compounds an suspension 250 ml sodium bicarbonate 3.5 g, gentamycin 47 mg, hydrocortisone 58 nystatin 3 000 UI mepivacaine 50 mg. <h3>Purpose</h3> The objective was to evaluate profile use mucositis compounded (MCS) with induced by...

<h3>Background</h3> Drug shortages are caused by many factors, therefore medicines errors reported. It is necessary to know how much health quality a concern of clinical practice and patient safety involved. <h3>Purpose</h3> To check out the drug supply problems; analyse characteristics assess their impact on medium-sized hospital. <h3>Material methods</h3> A retrospective study issues was conducted from September 2012 2014. Variables analysed: type drug, expected duration shortage...

<h3>Background</h3> The use of empiric antibiotics more selective than broad-spectrum is very frequent, which entails increased resistance in our environment. <h3>Purpose</h3> To evaluate the daptomycin patients with suspected infection complicated skin and soft-tissue infections (IPPBc), infectious endocarditis (EID) by meticilin resistant staphylococcus aureus (MRSA) or bacteremia MRSA associated EID IPPBc. <h3>Material methods</h3> Prospective longitudinal intervention study. We collected...

<h3>Background and importance</h3> Drug shortages (DS) are a current global health issue facing pharmacists, prescribers patients. To deal with DS, pharmacists forced to resort different suppliers manufacturers, or seek supplies abroad, in order guarantee treatment of <h3>Aim objectives</h3> analyse DS that affected second level hospital over 1 year (March 2018 March 2019) describe measures taken by the pharmacist them. <h3>Material methods</h3> This was descriptive, observational,...

<h3>Background and importance</h3> Dosing optimisation means therapeutic benefit with the lowest possible dose for each patient, improving patient adherence reducing adverse effects. <h3>Aim objectives</h3> To determine impact of an implantation tool in electronic medical history (ECHR) rheumatology patients being treated biologic drugs or without optimisation. <h3>Material methods</h3> The multidisciplinary team defined strategies based on reduction dosing interval. was designed to be...

<h3>Background and importance</h3> Clinical practice guidelines recommend oseltamivir in hospitalised patients with influenza but its use clinical is limited. <h3>Aim objectives</h3> To determine the criteria for of to analyse prescription concomitant antibiotics. <h3>Material methods</h3> An observational, descriptive, retrospective study was conducted treated (November 2018–February 2019) a second level hospital. Electronic medical history used as source information. Variables collected:...

<h3>Background and importance</h3> Selective cyclin dependent kinase (CDK) inhibitors, palbociclib ribociclib, were recently approved to treat advanced or metastatic breast cancer. The hospital pharmacist plays an important role in the revision of treatment at consultation, order ensure safety effectiveness treatment. <h3>Aim objectives</h3> To analyse potential drug interactions (PDI) before starting ribociclib evaluate physician acceptance recommendations. <h3>Material methods</h3> This...

<h3>Background and importance</h3> Medication errors (ME) are especially frequent in hospital emergency departments (ED). To minimise these ME, medication reconciliation programmes established, which analyse resolve the discrepancies detected regimen of patient. <h3>Aim objectives</h3> evaluate implementation programme ED a second level general hospital. <h3>Material methods</h3> An observational retrospective study was conducted. Records from patients admitted to observation area 1 January...