A5032230915- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Pharmaceutical Practices and Patient Outcomes
- Congenital Diaphragmatic Hernia Studies
- Patient Safety and Medication Errors
- Rheumatoid Arthritis Research and Therapies
- Obesity, Physical Activity, Diet
- Breastfeeding Practices and Influences
- Clinical Nutrition and Gastroenterology
- Health and Lifestyle Studies
- Respiratory Support and Mechanisms
- Safe Handling of Antineoplastic Drugs
- Cancer Treatment and Pharmacology
- Preterm Birth and Chorioamnionitis
- Congenital Anomalies and Fetal Surgery
- Pharmaceutical studies and practices
- Chemotherapy-induced cardiotoxicity and mitigation
- Hepatitis C virus research
- Tuberculosis Research and Epidemiology
- Botulinum Toxin and Related Neurological Disorders
- Orthopedic Infections and Treatments
- Neuroscience of respiration and sleep
- Gestational Diabetes Research and Management
- Child Nutrition and Water Access
- Pregnancy-related medical research
Universitat de Barcelona
2018-2025
Hospital General Universitario Gregorio Marañón
2016-2024
Hospital Sant Joan de Déu Barcelona
2014-2024
Hospital Clínic de Barcelona
2019-2024
Comunidad de Madrid
2024
Fundació Clínic per a la Recerca Biomèdica
2024
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2024
Hospital Universitario del Henares
2018
Hospital Universitario Fundación Jiménez Díaz
2001-2018
Sociedad Española de Farmacología Clínica
2018
Abstract Aim To develop and validate a feasible predictive model for early surfactant treatment in very preterm infants (VPI) admitted with respiratory distress syndrome (RDS). Methods Preterm less than 32 weeks of gestation RDS stabilized noninvasive ventilation delivery room were recruited (January 2018–April 2020). Clinical data, chest X‐ray (CXR) score, support, oxygen saturation/fraction inspired ratio (SF ratio), lung ultrasound (LUS) diaphragmatic thickening fraction (DTF) recorded at...
This study evaluated the impact of an exclusive human milk diet to nourish extremely low birth weight infants in neonatal intensive care unit.This multicenter pre-post retrospective included all inborn <1,000 g admitted four Level IV units either before or after implementing a donor policy. The feeding protocol was unchanged both periods. Collected data maternal/infant demographics, infant clinical data, and enteral intake as mother's own milk, formula.Two hundred one were enrolled. Infant...
<b><i>Introduction:</i></b> Lung ultrasound (LUS) is useful for respiratory management in very preterm infants (VPI), but little known about the echographic patterns bronchopulmonary dysplasia (BPD), relation between image findings, and severity of disease its long-term outcomes. We aimed to describe LUS BPD analyze accuracy predict need support at 36 weeks postmenstrual age (PMA) VPI. <b><i>Methods:</i></b> Preterm ≤30.6 gestational were...
Background Bronchopulmonary dysplasia (BPD) is a common cause of morbidity in preterm infants, leading to long-term respiratory complications and risk neurodevelopmental impairment. Although it has multifactorial etiology, local inflammation may play major role. Objectives. We aimed analyze the relationship between nasopharyngeal aspirate (NA) interleukin 6 (IL6) levels clinical imaging findings BPD. Methods: Pilot study infants < 30 weeks . NA was collected at 7 days life (DOL) serial...
Changes in lifestyle and diet have led to a progressive increase the prevalence of overweight obesity. This disorder can lead significant physical psychosocial effects that affect health related quality life (HRQOL). Adolescence is time great vulnerability very decisive personality development. The objective this study was assess influence weight status on HRQoL adolescents.A cross-sectional conducted adolescents 12-16 years old an assessment HRQOL using CHIP-Adolescents Edition...
Background: We report the long-term outcomes, changes in laboratory parameters, incidence of secondary nosocomial infections and treatment cost a Spanish cohort patients with severe COVID-19 that received tocilizumab (TCZ).
Abiraterone and enzalutamide, androgen receptor pathway inhibitors (ARPI) for the treatment of metastatic castration-resistant prostate cancer (mCRPC), are at high risk potential drug interactions (PDIs). We aimed to describe PDIs their management, triggered adverse events (AEs) in clinical practice.We conducted a cross-sectional study mCRPC patients who started with abiraterone or enzalutamide university hospital between August 1st, 2016 July 31st, 2020. Lexicomp® was used identify analyze...
Abstract Objective To identify changes in macronutrient content of very preterm human milk associated with perinatal factors. Study design Milk macronutrients were measured on weeks 1, 2, 4 and 8 mid-infrared transmission spectrometers. Result We assessed 625 samples (from 117 mothers 130 infants). Average concentrations were: protein 1.3 ± 0.3 g/dl, carbohydrates 7.3 0.6 fat 3.7 1.0 g/dl energy 296.0 41.0 kJ/dl (70.7 kcal/dl). Gestational age negatively correlated ( rho : −0.307, p <...
Abstract Purpose The design, implementation, and assessment of a comprehensive pharmaceutical care program (CPCP) for hepatitis C virus (HCV)-infected patients treated with direct-acting antivirals (DAA) are described. Summary advent DAA regimens has caused the evolution role hospital pharmacists, leading to development more specialized models care. Three clinical pharmacists were incorporated into pharmacy department general tertiary teaching in Madrid, Spain, aim developing implementing...
Background: No previous studies exist examining the effectiveness and safety in real clinical practice of combination ombitasvir/paritaprevir/ritonavir dasabuvir (OBV/PTV/r+DSV). Objective: To evaluate OBV/PTV/r+DSV with or without ribavirin for 12 weeks treatment-naïve previously treated adult patients chronic hepatitis C virus (HCV) genotype 1 infection. Methods: This was an observational study a prospective cohort pretreated who received OBV/PTV/r (25/150/100 mg once daily) DSV (250 twice...
Introduction Osimertinib is a third-generation tyrosine kinase inhibitor (TKI) indicated for the treatment of epidermal growth factor receptor mutated non-small cell lung cancer (NSCLC). It has demonstrated better results concerning effectiveness than other TKIs same indication. However, despite good safety profile, it could produce some cardiotoxicity that does not occur with drugs group. Case report We evolution and management female patient diagnosed NSCLC who developed grade 3 due to...
Nutritional complications have an impact in both short- and long-term morbidity of patients with congenital diaphragmatic hernia (CDH). We aimed to compare time full enteral tube feeding depending on route -gastric (GT) or transpyloric (TPT)- newborns left CDH (L-CDH).Retrospective cohort study L-CDH admitted a referral tertiary care NICU between January 2007 December 2014. Lethal chromosomal abnormalities death before initiation nutrition were exclusion criteria.37 fed through GT, 46 by...