A5067530197- Congenital Diaphragmatic Hernia Studies
- Congenital Anomalies and Fetal Surgery
- Tracheal and airway disorders
- Esophageal and GI Pathology
- Neonatal Respiratory Health Research
- Intestinal Malrotation and Obstruction Disorders
- Urological Disorders and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Congenital gastrointestinal and neural anomalies
- Allergic Rhinitis and Sensitization
- Hernia repair and management
- Tumors and Oncological Cases
- Cardiac, Anesthesia and Surgical Outcomes
- Asthma and respiratory diseases
- COVID-19 and healthcare impacts
- Drug-Induced Adverse Reactions
- Viral gastroenteritis research and epidemiology
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Use and Resistance
- Hip and Femur Fractures
- Urologic and reproductive health conditions
- Digestive system and related health
- Dysphagia Assessment and Management
- Infant Nutrition and Health
- Inflammatory mediators and NSAID effects
Hospital Sant Joan de Déu Barcelona
2012-2025
Universitat de Barcelona
2003-2024
Centre for Biomedical Network Research on Rare Diseases
2024
Bellvitge University Hospital
2003
Hospital Clínic de Barcelona
1993
BackgroundCongenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital fatal without timely access to neonatal surgical care, but few studies have been done on these conditions low-income and middle-income countries (LMICs). We compared outcomes seven most common low-income, middle-income, high-income globally, identified factors associated with mortality.MethodsWe did a multicentre, international prospective cohort...
Although the mechanism of aspirin-induced asthma and rhinitis is unknown, it has been suggested that adverse nasal bronchial reactions are caused by an increased production lipoxygenase products. In examining this hypothesis we have measured release peptide leukotrienes (PeptLTs), 15-HETE, prostaglandins in fluids obtained lavages after instillation acetylsalycilic acid (ASA) placebo (saline). Ten ASA-sensitive asthmatics, 10 ASA-insensitive seven healthy subjects were challenged a...
Transition of care (TOC; from childhood into adulthood) patients with anorectal malformations (ARM) and Hirschsprung disease (HD) ensures continuation for these patients. The aim this international study was to assess the current status TOC adult (AC) programs ARM HD.A survey developed by members EUPSA, ERN eUROGEN, ERNICA, including patient representatives (ePAGs), comprising four domains: general information, questions about transition adulthood, disease-specific regarding AC programs....
Objective: Congenital high airway obstruction syndrome (CHAOS) normally has a dire prognosis due to laryngeal atresia and association with other anomalies. However, rare cases an isolated tracheal membrane have been described. We assessed systematically the larynx vocal cords in fetuses CHAOS, goal of identifying such attempting fetoscopic deobstruction. Methods: Between 2008 2012, 7 CHAOS were referred our institution. The ultrasonographic aspect trachea was assessed. report ultrasound...
<title>Abstract</title> Purpose: Frenotomy is the procedure of choice for treating ankyloglossia. The literature reports that readhesion frenulum occurs in 2.6-13% cases. There no published evidence to support performing tongue exercises prevent this readhesion. We routinely recommend parents perform them. aimed determine recurrence rate ankyloglossia necessitating a refrenotomy and benefits massage prevention Methods: Prospective, observational study neonates who underwent frenotomy between...
This is the first report of fetoscopy to successfully treat a case bilobar bronchial atresia presenting in form massive right lung tumor causing severe thoracic compression with mediastinal shift, pulmonary hypoplasia and eventually fetal hydrops. The presence an echolucent tubular structure hilum was identified as intrapulmonary continuation interrupted main bronchus, led diagnosis atresia. After extensive discussion counseling, fetoscopic operation designed indicated. procedure consisted...
<i>Objective:</i> To analyze the impact of in utero tracheal occlusion (TO) on lung tissue blood perfusion, as measured by fractional moving volume (FMBV) and conventional spectral Doppler, a rabbit model congenital diaphragmatic hernia (CDH). <i>Methods:</i> In 50 fetal rabbits, left CDH was surgically created at 23 days gestational age (GA). At 28 GA, surviving fetuses were randomly assigned to undergo either TO (CDH+TO group) or sham operation (CDH group). Twenty...
• An embryonal rhabdomyosarcoma that initially was seen as a polyp in the external auditory canal underwent uncontrollable direct extension along facial nerve through internal meatus, with encasement of base brain and entire spinal cord despite radical surgery, supervoltage irradiation, multidrug chemotherapy. This degree massive neuraxial spread without systemic metastases appears to be unique. (<i>Arch Otolaryngol</i>103:301-303, 1977)
We report our experience in the postnatal management of congenital diaphragmatic hernia (CDH) after fetal endoluminal balloon tracheal occlusion (FETO).Out 19 CDH fetuses diagnosed since December 2005, 13 had a lung-to-head ratio (LHR) < 1.1 (0.86 +/- 0.11) and underwent FETO at mean gestational age (GA) 27.9 weeks. The was removed 3 cases through puncture EXIT (ex utero intrapartum treatment); there were trans-utero punctures, fetoscopies balloons deflated spontaneously. One patient died...
An abnormal platelet release of oxygen-free radicals has been described in acetylsalicylic acid (aspirin)-induced asthma, a finding which might suggest the existence an intrinsic, specific abnormality arachidonic metabolism these patients. The objective this study was to evaluate asthmatic patients with or without intolerance aspirin.Thirty subjects distributed into three groups were studied: group 1, 10 healthy subjects; 2, aspirin tolerance; and 3, aspirin-intolerant asthmatics. Platelets...
For evaluation of two methods nasal cell identification, morphology and immunocytologic analysis, lavage was performed in 16 healthy subjects 29 patients suffering from rhinitis. Nasal smears were stained with May‐Grünwald‐Giemsa (MGG), cells identified according to their structure as epithelial cells, neutrophils, lymphocytes, eosinophils, metachromatic (basophils mast cells). Immunocytologic analysis monoclonal antibodies by the immunoalkaline phosphatase method. The following used: CK1,...
Nutritional complications have an impact in both short- and long-term morbidity of patients with congenital diaphragmatic hernia (CDH). We aimed to compare time full enteral tube feeding depending on route -gastric (GT) or transpyloric (TPT)- newborns left CDH (L-CDH).Retrospective cohort study L-CDH admitted a referral tertiary care NICU between January 2007 December 2014. Lethal chromosomal abnormalities death before initiation nutrition were exclusion criteria.37 fed through GT, 46 by...
The effectiveness of antimicrobial stewardship programs (ASP) in reducing use (AU) children has been proved. Many interventions have described suitable for different institution sizes, priorities, and patients, with surgical wards being one the areas that may benefit most. We aimed to describe results on AU length stay (LOS) a pre-post study during three years before (2014–2016) after (2017–2019) implementation an ASP based postprescription review feedback adolescents admitted...