Irene Bretón Lesmes

ORCID: 0000-0003-0263-3728
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About
Contact & Profiles
Research Areas
  • Nutrition and Health in Aging
  • Clinical Nutrition and Gastroenterology
  • Diet and metabolism studies
  • Bariatric Surgery and Outcomes
  • Health and Lifestyle Studies
  • Nutritional Studies and Diet
  • Body Contouring and Surgery
  • Body Composition Measurement Techniques
  • Healthcare Systems and Technology
  • Obesity and Health Practices
  • Obesity, Physical Activity, Diet
  • Muscle metabolism and nutrition
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Pharmacology and Obesity Treatment
  • Child Nutrition and Feeding Issues
  • Diabetes Treatment and Management
  • Dysphagia Assessment and Management
  • Vitamin C and Antioxidants Research
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • Amyotrophic Lateral Sclerosis Research
  • Mercury impact and mitigation studies
  • Pituitary Gland Disorders and Treatments
  • Frailty in Older Adults
  • Intensive Care Unit Cognitive Disorders

Hospital General Universitario Gregorio Marañón
2016-2025

Nestlé (Switzerland)
2010-2024

École Polytechnique Fédérale de Lausanne
2024

Universidad Complutense de Madrid
2021-2024

Sociedad Española de Endocrinología y Nutrición
2014-2023

Unité de Nutrition Humaine
2005-2023

Federación Española de Enfermedades Raras
2014

Madrid Health Service
2012

Massey University
2011

Victoria School of Management
2011

Background: A nationwide, prospective, multicenter, cohort study (the Disease-Related caloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness of ultrasound rectus femoris for detecting sarcopenia in hospitalized patients at risk and define cut-off values measures. Methods: Patients according Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry, bioelectrical impedance analysis (BIA), a Timed Up Go (TUG) test, studies. European...

10.3390/nu16111552 article EN Nutrients 2024-05-21

Background/Objectives: Decompensated cirrhosis is characterized by systemic inflammation and innate adaptive immune dysfunction. Hepatic encephalopathy (HE) a prevalent debilitating condition cognitive disturbances in which ammonia play synergistic pathogenic role. Extraskeletal functions of vitamin D include immunomodulation, its deficiency has been implicated dysfunction different forms impairment. The aim was to assess changes function decompensated patients with receiving...

10.3390/nu17020226 article EN Nutrients 2025-01-09

Hyperglycemia may increase mortality in patients who receive total parenteral nutrition (TPN). However, this has not been well studied noncritically ill (i.e., the nonintensive care unit setting). The aim of study was to determine whether mean blood glucose level during TPN infusion is associated with increased hospitalized patients.This prospective multicenter involved 19 Spanish hospitals. Noncritically were prescribed included prospectively, and data collected on demographic, clinical,...

10.2337/dc12-1379 article EN cc-by-nc-nd Diabetes Care 2012-12-07

The pathogenesis of enteritis after abdominal radiotherapy is unknown, although changes in faecal microbiota may be involved. In several studies, Lactobacillus and Bifidobacterium have proven beneficial for the host. Prebiotics stimulate proliferation Bifidobacterium, this positive effects on intestinal mucosa during radiotherapy.We performed a randomised double-blind, placebo-controlled trial including 31 patients with gynaecological cancer who received (29 sessions, 52.2 Gy) surgery....

10.3305/nh.2012.27.6.5992 article EN PubMed 2013-04-17

Human age-related diseases, including obesity and type 2 diabetes (T2DM), have long been associated to mitochondrial dysfunction; however, the role for adipose tissue mitochondria in these conditions remains unknown. We tackled impact of aging T2DM on adipocyte from obese patients by quantitating not only corresponding abundance changes proteins, but also redox alterations undergone Cys residues thereof. For that, we resorted a high-throughput proteomic approach based isobaric labeling,...

10.1016/j.redox.2016.12.013 article EN cc-by-nc-nd Redox Biology 2016-12-18

The European Society for Clinical Nutrition and Metabolism published its first clinical guidelines use of micronutrients (MNs) in 2022. A two-day web symposium was organized November 2022 discussing how to apply the practice. present paper reports main findings this symposium.

10.1016/j.clnu.2023.12.006 article EN cc-by Clinical Nutrition 2023-12-09

Abstract A probiotic-related benefit for the host is inherently linked to metabolic activity and integration in gut ecosystem. To facilitate these, probiotics are often combined with specific prebiotics a synbiotic formulation. Here, we propose an approach improving probiotic engraftment. By cultivating strain presence of prebiotic (preconditioning), bacterial enzymatic machinery geared towards consumption. Today, it not known if preconditioning constitutes advantage concept. Therefore,...

10.1038/s41598-024-54887-z article EN cc-by Scientific Reports 2024-02-21

This paper presents baseline results from the NutriEcoMuscle study, a multicenter observational study conducted in Spain which focused on changes nutritional status, body composition, and functionality post-intensive care unit (ICU) COVID-19 patients following intervention. Assessments at hospital discharge included Subjective Global Assessment (SGA), Leadership Initiative Malnutrition (GLIM) criteria, Barthel index, handgrip strength (HGS) Timed Up-and-Go test, bioelectrical impedance...

10.3390/nu16060886 article EN Nutrients 2024-03-19

Purpose This study aimed to determine the effect of postexercise protein–leucine coingestion with CHO–lipid on subsequent high-intensity endurance performance and investigate candidate mechanisms using stable isotope methods metabolomics. Methods In this double-blind, randomized, crossover study, 12 male cyclists ingested a leucine/protein/CHO/fat supplement (LEUPRO 7.5/20/89/22 g·h−1, respectively) or isocaloric CHO/fat control (119/22 g·h−1) 1–3 h after exercise during 6-d training block...

10.1249/mss.0b013e3182290371 article EN Medicine & Science in Sports & Exercise 2011-06-17
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