A5089422769- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Diet and metabolism studies
- Body Composition Measurement Techniques
- Frailty in Older Adults
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Nutrition, Genetics, and Disease
- Diabetes Management and Research
- Thyroid Cancer Diagnosis and Treatment
- Amyotrophic Lateral Sclerosis Research
- Neurogenetic and Muscular Disorders Research
- Bariatric Surgery and Outcomes
- Bone health and osteoporosis research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Dysphagia Assessment and Management
- Child Nutrition and Feeding Issues
- Vitamin D Research Studies
- Diabetes Treatment and Management
- Regulation of Appetite and Obesity
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
Hospital Clínico Universitario de Valladolid
2016-2025
Universidad de Valladolid
2016-2025
Complejo Asistencial Universitario de Palencia
2011-2025
University of Miami
2024
Sociedad Española de Endocrinología y Nutrición
2015-2022
Hospital Universitario Río Hortega
2021
Universidad Católica de El Salvador
2020
Clínica Santa María
2017
Hospital General San Jorge
2016
Universidad de León
2012
To evaluate the addition of paclitaxel to an anthracycline-based adjuvant regimen and compare this combination with same given as primary systemic (neoadjuvant) therapy.A total 1,355 women operable breast cancer were randomly assigned one three treatments: surgery followed by doxorubicin (75 mg/m(2)) cyclophosphamide, methotrexate, fluorouracil (CMF; arm A); (200 plus (60 mg/m(2)), CMF (arm B); or C). The two coprimary objectives assess effects on relapse-free survival (RFS) postoperative...
To determine distribution and function of cardiac angiotensin (ANG) II receptor AT1 AT2 subtypes in left ventricular (LV) hypertrophy (LVH), ANG (10(-8) M) was infused into isolated rat hearts with from aortic banding sham-operated controls. alone or the presence inhibitor [losartan (10(-5) CL-329167 (10(-7) M)] [CG-42112A M]. caused less increase coronary vascular resistance (CVR) LVH compared control (19 vs. 39%; P < 0.01), although baseline CVR higher hearts. This prevented by but not...
Background: A nationwide, prospective, multicenter, cohort study (the Disease-Related caloric-protein malnutrition EChOgraphy (DRECO) study) was designed to assess the usefulness of ultrasound rectus femoris for detecting sarcopenia in hospitalized patients at risk and define cut-off values measures. Methods: Patients according Malnutrition Universal Screening Tool (MUST) underwent handgrip dynamometry, bioelectrical impedance analysis (BIA), a Timed Up Go (TUG) test, studies. European...
The European Cooperative Trial in Operable breast cancer (ECTO) randomly tested whether efficacy of adjuvant doxorubicin followed by i.v. cyclophosphamide, methotrexate, and fluorouracil (CMF; doxorubicin-->CMF, arm A) could be improved adding paclitaxel (doxorubicin/paclitaxel-->CMF) as (arm B) or primary systemic therapy (PST, C). We report here feasibility, tolerability, locoregional antitumor activity, conservation rate.A total 1,355 women entered the study. Feasibility safety were...
(1) Background: The aim was to validate an AI-based system compared the classic method of reading ultrasound images rectus femur (RF) muscle in a real cohort patients with disease-related malnutrition. (2) Methods: One hundred adult DRM aged 18 85 years were enrolled. risk assessed by Global Leadership Initiative on Malnutrition (GLIM). variation, reproducibility, and reliability measurements for RF subcutaneous fat thickness (SFT), (MT), cross-sectional area (CSA), measured conventionally...
Epstein and Eckoff in 1967 devised a scheme to summarize population differences the rise of mean values systolic blood pressure by age accordance with their slopes levels. For first time, validity this can be examined data from single study, INTERSALT. This study included 52 populations 32 countries. On basis these data, collected an exceptionally well-standardized mode under common protocol, diversity median has been strongly reconfirmed. Populations no increase were again observed remained...
Objective: the COVID-19 pandemic, by restricting population mobility, may exacerbate risk factors for weight gain associated with physical inactivity and increased consumption of calorie-dense foods. The aim this cross-sectional study was to evaluate related self-reported body among obese subjects. Methods: involved a 284 adult After 7-week confinement period starting on March 17, telephone interview (May 4 through 7) conducted. In phone call, number were recorded. order obtain baseline data...
Objectives: The aim of this investigation was to evaluate the discrepancies between bioelectrical impedance analysis (BIA) and computed tomography (CT) in assessing skeletal muscle mass identifying low patients with colorectal cancer. Methods: This study recruited 137 cancer from February 2028 December 2023. CT scans were analyzed at Lumbar 3 vertebral level determine area muscle, which then utilized estimate whole-body mass. [BIA] also employed measure muscle. Both values [kg] divided by...
Many elderly patients with COVID-19 are at risk of malnutrition. The aim our study was to evaluate the malnutrition and sarcopenia in R-MAPP (Remote-Malnutrition APP).A cross-sectional 337 consecutive outpatients ≥65 years who attended Central Emergency Hospital Castilla y Leon conducted. In all patients, protocol (Malnutrition Universal Screening Tool [MUST] Simple Questionnaire Rapidly Diagnose Sarcopenia [SARC-F]) realized.The mean age 86.1 ± 8.7 years, a sex distribution 167 males...
Background and aims: The relationship between obesity bone metabolism is controversial. In recent decades, the protective role of in development osteoporosis questioned. aims this study are following: to evaluate differences turnover markers postmenopausal women with without compare risk fracture at five years these groups. Methods: An observational longitudinal prospective cohort (O) (body mass index (BMI) > 30 kg/m2) non-obesity (NoO) (BMI < designed. 250 included (NoO: 124 (49.6%) O: 126...
Nutritional ultrasonography is an emerging technique for measuring muscle mass and quality. The study aimed to evaluate the relationship between parameters of body quality with other morphofunctional assessment in patients disease-related malnutrition (DRM).
Amyotrophic lateral sclerosis (ALS) is a progressive disease with high prevalence of malnutrition that can influence prognosis. The main objective this study to compare the validity muscle ultrasonography in diagnosis and prognosis patients ALS. Methods: This prospective observational analyzes nutritional status at beginning monitoring. morphofunctional assessment included examination anthropometric variables such as weight, height, body mass index (BMI), arm circumference, calf...
Introduction: Some studies have demonstrated the effect of rs7903146 genetic variant on weight response after different dietary strategies. The objective our study was to evaluate role this TCF7L2 gene loss and diabetes mellitus progression following a partial meal replacement (pMR) hypocaloric diet. Methods: We conducted an interventional in 214 subjects with obesity body mass index (BMI) > 35 kg/m². received two servings per day normocaloric hyperproteic formula for 24 weeks as part pMR...
Abstract Background The relative contribution of the different components mechanical power to mortality is a subject debate and has not been studied in COVID-19. aim this study evaluate both total impact each on well-characterized cohort patients with COVID-19-induced acute respiratory failure undergoing invasive ventilation. This secondary analysis CIBERESUCICOVID project, multicenter observational including fifty Spanish intensive care units that included COVID-19 mechanically ventilated...