- Ocular Oncology and Treatments
- Pancreatitis Pathology and Treatment
- Health and Lifestyle Studies
- Blood Pressure and Hypertension Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Musculoskeletal pain and rehabilitation
- Gastrointestinal disorders and treatments
- Ocular Infections and Treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Corneal Surgery and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Acute Ischemic Stroke Management
- Colorectal Cancer Screening and Detection
- Infective Endocarditis Diagnosis and Management
- Gallbladder and Bile Duct Disorders
- Retinal Development and Disorders
- Pancreatic and Hepatic Oncology Research
- Retinal Diseases and Treatments
- Sepsis Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- COVID-19 Clinical Research Studies
- Brain Metastases and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
Universidad de Valladolid
2013-2025
Hospital Clínico Universitario de Valladolid
2015-2024
Hospital Universitari Germans Trias i Pujol
2013-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2024
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2024
Instituto de Estudios de Ciencias de la Salud de Castilla y León
2021
Hospital de Poniente
2020
Vall d'Hebron Hospital Universitari
2017
Universitat Pompeu Fabra
2014
Mines Saint-Étienne
2012
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Over the last few years, most of attempts to introduce active learning methodologies in classroom have made use Information and Communication Technology (ICT). Many these efforts been directed collaborative scenarios used remote, blended or face-to-face experiences, order take advantage flexibility provided by ICT. However competitive could also some positive effects on success process, be added...
Pneumonia is the leading cause of hospital admission and mortality in coronavirus disease 2019 (COVID-19). We aimed to identify cytokines responsible for lung damage mortality. prospectively recruited 108 COVID-19 patients between March April 2020 divided them into four groups according severity respiratory symptoms. Twenty-eight healthy volunteers were used normalization results. Multiple showed statistically significant differences mild critical patients. High HGF levels associated with...
Background and purpose Perfusion‐computed tomography‐source images ( PCT ‐ SI ) may allow a dynamic assessment of leptomeningeal collateral arteries LMC filling emptying in middle cerebral artery MCA ischaemic stroke. We described regional scale on hypothesized that higher score would predict better response to intravenous (iv) thrombolysis. Methods studied consecutive stroke patients with an acute occlusion documented by transcranial Doppler/transcranial color‐coded duplex, treated iv...
Objectives: The aim of this investigation was to evaluate the discrepancies between bioelectrical impedance analysis (BIA) and computed tomography (CT) in assessing skeletal muscle mass identifying low patients with colorectal cancer. Methods: This study recruited 137 cancer from February 2028 December 2023. CT scans were analyzed at Lumbar 3 vertebral level determine area muscle, which then utilized estimate whole-body mass. [BIA] also employed measure muscle. Both values [kg] divided by...
Selection of best responders to reperfusion therapies could be aided by predicting the duration tissue-at-risk viability, which may dependant on collateral circulation status. We aimed identify predictor good among perfusion computed tomography (PCT) parameters in middle cerebral artery (MCA) ischemic stroke and analyze how early MCA response intravenous thrombolysis PCT-derived markers collaterals interact determine outcome.We prospectively studied patients with acute treated who underwent...
To estimate the attributable and targeted avoidable deaths (ADs; TADs) of outdoor air pollution by ambient particulate matter (PM10), PM2.5 O3 according to specific WHO methodology.Health impact assessment.City Valladolid, Spain (around 300 000 residents).Demographics; mortality; pollutant concentrations collected 1999-2008.Attributable fractions; ADs TADs per year for 1999-2008.Higher estimates (shown here) were obtained when assuming as 'target' Air Quality Guidelines instead Directive...
Major changes have occurred in the epidemiology and etiology of infective endocarditis (IE). Nevertheless, differences between nosocomial (NIE) community-acquired (CIE) not been addressed a population-based study. We conducted retrospective, nationwide, temporal trend study from 1997 to 2014 analyzing epidemiology, clinical, geographical, meteorological characteristics patients diagnosed with IE Spain, distinguish NIE CIE. Among 25,952 (62.2 ± 18·6 years; 65.9% men), 45.9% had NIE. The...
<b><i>Background:</i></b> Extending the therapeutic window of intravenous thrombolysis for acute ischemic stroke beyond established 4.5-hour limit is critical importance in order to increase proportion thrombolysed patients. In this setting, capacity MRI select patients reperfusion therapies delayed time windows has been and being tested clinical trials. However, whether more available cost-effective perfusion computed tomography (PCT) may be useful candidates remains...
To detect whether signs of oxidative stress appear at early stages colorectal adenocarcinoma (CRC), particularly in the polyp stage. We also aimed to evaluate specific entities myeloperoxidase (MPO) and oxidized low-density lipoprotein (oxLDL) as novel markers oxidation plasma patients with CRC study relationship between status patient survival.We assayed serum or specimens from healthy control subjects (n = 14), intestinal polyps 39), 128) calculate modified balance score (MOBS) using...
To analyze clinical and histopathological prognostic factors overall specific survival after enucleation in a Spanish cohort diagnosed with uveal melanoma. A prospective analysis was performed single-center case series of 138 patients posterior melanoma seen the Adult Intraocular Tumour Unit at University Clinical Hospital Valladolid treated by as primary treatment between January 2006 December 2021. Kaplan-Meier Cox regression analyses were to identify factors. Mean follow-up time 54...
Purpose This study aimed to assess the complication rate of porous polyethylene (PP) implants in patients who underwent enucleation for uveal melanoma and explore link between complications surgical factors. Methods A retrospective cohort was conducted on consecutive cases treated at Ocular Oncology Unit, University Clinical Hospital Valladolid, from 1995 2023. Complications were classified as mild (managed conservatively) or severe (requiring implant removal replacement). Kaplan-Meier...
ResumenConsumo de sustancias adictivas en los adolescentes 13 a 18 años y otras conductas riesgo relacionadas Introduction: one of the most important problems in our public health system nowadays is drug consumption and risky behaviors related to it.Objective: analyze prevalence adolescents attending high school province Valladolid its relation with other factors.Material methods: 101 question survey about alcohol consumption, performance, leisure time, accidents, tobacco, drugs,...
Purpose To design and validate a standard, simple, reliable iris color classification to study its distribution in Spanish population. Iris has geographic been correlated with different ocular diseases. However, there is no standard validated allowing comparison among studies. Methods Classification was made three grades (blue-gray, hazel-green, brown) by 3 independent readers. Initially, preliminary 50 photographs detect technical hitches. Afterwards, based on this procedure, 221 were...