A5016531940- Transplantation: Methods and Outcomes
- Tracheal and airway disorders
- Cystic Fibrosis Research Advances
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Polyomavirus and related diseases
- Respiratory viral infections research
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Airway Management and Intubation Techniques
- Mechanical Circulatory Support Devices
- Immunodeficiency and Autoimmune Disorders
- Pleural and Pulmonary Diseases
- Trauma Management and Diagnosis
- Myasthenia Gravis and Thymoma
- Lung Cancer Treatments and Mutations
- Organ and Tissue Transplantation Research
- Pneumonia and Respiratory Infections
- Genetic and Kidney Cyst Diseases
- Thyroid and Parathyroid Surgery
- Pediatric health and respiratory diseases
- Pneumocystis jirovecii pneumonia detection and treatment
University of Córdoba
1994-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2013-2025
Hospital Universitario Reina Sofía
2012-2024
Vall d'Hebron Hospital Universitari
2005-2023
Universitat Autònoma de Barcelona
1998-2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2009-2023
Vall d'Hebron Institut de Recerca
2016-2023
Hospital Quirónsalud Barcelona
2021-2022
Atos (Spain)
2022
Hopitaux Civils de Colmar
2022
Elexacaftor–tezacaftor–ivacaftor is a small-molecule cystic fibrosis transmembrane conductance regulator (CFTR) modulator regimen shown to be efficacious in patients with at least one Phe508del allele, which indicates that this combination can modulate single allele. In whose other CFTR allele contains gating or residual function mutation already effectively treated previous modulators (ivacaftor tezacaftor–ivacaftor), the potential for additional benefit from restoring protein unclear.
Whether discernible advantages in terms of sensitivity and specificity exist with Acute Kidney Injury Network (AKIN) criteria versus Risk, Injury, Failure, Loss Function, End-stage Disease (RIFLE) is currently unknown. We evaluated the incidence acute kidney injury compared ability maximum RIFLE AKIN within intensive care unit hospitalization predicting inhospital mortality critically ill patients.Patients admitted to Department Intensive Medicine our hospital between January 2003 December...
Keeping airways clear of mucus by airway clearance techniques seems essential in bronchiectasis treatment, although no placebo-controlled trials or any studies lasting longer than 3 months have been conducted. We evaluate the efficacy ELTGOL (slow expiration with glottis opened lateral posture) technique over a 1-year period patients chronic expectoration randomised trial. Patients were to perform (n=22) placebo exercises twice-daily (ClinicalTrials.gov, NCT01578681 ). The primary outcome...
This analysis aimed to evaluate perioperative outcomes of surgical resection following neoadjuvant treatment with chemotherapy plus nivolumab in resectable stage IIIA non-small-cell lung cancer.Eligible patients received (paclitaxel + carboplatin) for 3 cycles. Reassessment the tumour was carried out after and at least stable disease as best response underwent pulmonary resection. After surgery, adjuvant 1 year. Surgical data were collected from NADIM database patient charts reviewed...
Some studies have reported a high prevalence of bronchiectasis in patients with uncontrolled asthma, but the factors associated this condition are unknown. The objective study was to determine moderate-to-severe asthma and identify risk their correlation these patients. This is prospective data from consecutive asthma. Diagnosis based on high-resolution computed tomography. A prognostic score developed using logistic regression model, which used bronchiectasis. total 398 (60% severe asthma)...
Cerebral tissue from hemispherectomy in three children (two 4-month-old girls and one 4-year-old boy) with hemimegalencephaly was studied using histochemical immunocytochemical markers of neuronal glial maturation identity. Histologic abnormalities cellular growth cytomorphology, including "balloon cells," were present both gray white matter, addition to disorganized architecture. Cells the mitotic cycle absent. Many hypertrophic, atypical cells enlarged processes exhibited mixed or...
Airway complications (AC) remain a significant contributing factor of morbidity after lung transplantation (LT). The aim this study was to identify risk factors for AC, and review the outcomes endoscopic surgical treatment.From 1993 2006, 255 patients underwent LT. Seven retransplants 34 not surviving beyond 7 days were excluded. remaining were: 124 double LT (DLT), 85 single (SLT), 3 lobar 2 liver-DLT, comprising 343 bronchial anastomoses at risk. Donor lungs flushed with either modified...
In 2012, the European Society of Thoracic Surgeons (ESTS) created Lung Neuroendocrine Tumors Working Group (NETs-WG) with aim to develop scientific knowledge on clinical management such rare neoplasms. This paper outlines outcome and prognostic factors two aggressive NETs: atypical carcinoids (ACs) large-cell neuroendocrine carcinomas (LCNCs). Using ESTS NETs-WG database, we retrospectively collected data 261 patients in seven institutions Europe, between 1994 2011. We used a Cox regression...
Acute kidney injury (AKI) has increasingly been recognized as an important public health issue due to its rising frequency, associations with early and late adverse outcomes economic burden. Given the importance of determining available resources address this serious issue, AKI Committee SLANH conducted a survey obtain information about infrastructure, human equipment devoted treatment in Latin America A total 246 units from 14 countries participated survey, majority them pertaining...
Primary ciliary dyskinesia, with or without situs abnormalities, is a rare lung disease that can lead to an irreversible damage may progress respiratory failure. Lung transplant be considered in end-stage disease. This study describes the outcomes of largest population for PCD and also identified as Kartagener’s syndrome. Retrospectively collected data 36 patients who underwent transplantation from 1995 2020 SA part European Society Thoracic Surgeons Transplantation Working Group on...
Cystic fibrosis (CF) is a chronic disease in which the bacterial colonization of lung linked to an excessive inflammatory response that leads respiratory failure. The microbiology CF complex. Staphylococcus aureus first bacterium colonize lungs 30% pediatric patients, and 80% adult patients develop Pseudomonas aeruginosa infection, but other microorganisms can also be found. use antibiotics essential treat disease, antibiotic performance compromised by resistance mechanisms. Among various...
The Leicester Cough Questionnaire (LCQ) has been validated in non-cystic fibrosis bronchiectasis (NCFBC). present study aimed to create and validate a Spanish version of the LCQ (LCQ-Sp) NCFBC. LCQ-Sp was developed following standardized protocol. For reliability, we assessed internal consistency change score over 15-day period stable state. responsiveness, scores between visit 1 first exacerbation. validity, evaluated convergent validity through correlation with Saint George’s Respiratory...
Background: Pulmonary rehabilitation is recognized widely as one of the most effective measures to promote postoperative recovery lung transplant recipients (LTRs), and it has positive effects on both short- long-term quality life (QoL) survival outcomes. However, no standardized pulmonary training programs exist specifically for LTRs. The used in clinical practice focus mainly exercise or respiratory training, some extent neglecting other therapeutic methods that could patient health, such...
The main limitation to increased rates of lung transplantation (LT) continues be the availability suitable donors. At present, largest source allografts is still donation after neurologic determination death (brain-death donors, DBD). However, only 20% these donors provide acceptable for transplantation. One proposed strategies increase donor pool use circulatory-determination-of-death (DCD), which has potential significantly alleviate shortage transplantable lungs. According Maastricht...
Once the Tajogaite eruption was over in December 13, 2021, INVOLCAN continued monitoring visible volcanic emanations. To do so, active situ/remote techniques were undertaken based on different methodologies: direct sampling, alkaline traps, Multi-GAS and miniDOAS. These methods are suitable tools to provide as much information possible emitted gases. Direct gas sampling performed at two degassing sites, F1 F2, by collecting samples burying a glass funnel point using TEDLAR bags for later...