- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Mechanical Circulatory Support Devices
- Lung Cancer Diagnosis and Treatment
- Mesenchymal stem cell research
- Organ and Tissue Transplantation Research
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Pleural and Pulmonary Diseases
- Polyomavirus and related diseases
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease and Transplantation
- Tissue Engineering and Regenerative Medicine
- Organ Donation and Transplantation
- Sarcoma Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Pectus Deformity Diagnosis and Treatment
- Ear and Head Tumors
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Enhanced Recovery After Surgery
- Neurogenetic and Muscular Disorders Research
- Nutrition and Health in Aging
- Cardiac Arrest and Resuscitation
- Clinical Nutrition and Gastroenterology
Hospital Universitario 12 De Octubre
2024-2025
Hospital Universitario Puerta de Hierro Majadahonda
2013-2024
Universidad Europea
2023-2024
Toronto General Hospital
2022-2023
Universidad Autónoma de Madrid
2021
University Health Network
2020
University of Toronto
2020
Marqués de Valdecilla University Hospital
2012
This analysis aimed to evaluate perioperative outcomes of surgical resection following neoadjuvant treatment with chemotherapy plus nivolumab in resectable stage IIIA non-small-cell lung cancer.Eligible patients received (paclitaxel + carboplatin) for 3 cycles. Reassessment the tumour was carried out after and at least stable disease as best response underwent pulmonary resection. After surgery, adjuvant 1 year. Surgical data were collected from NADIM database patient charts reviewed...
BACKGROUND: Lung transplantation is performed on a 24/7 schedule to minimize organ ischemic time. Recent preclinical studies demonstrated superior graft preservation at 10°C compared with storage in an ice cooler (gold standard). METHODS: In this prospective, multicenter, nonrandomized clinical trial, we studied transplants from donors overnight cross-clamp times (6:00 p.m. 4:00 a.m.) that had earliest allowed starting time of 6:00 a.m. Lungs meeting criteria for were retrieved, transported,...
Recent advances in the treatment of locally advanced NSCLC have led to changes standard care for this disease. For selection best approach strategy each patient, it is necessary homogenization diagnostic and therapeutic interventions, as well promotion evaluation patients by a multidisciplinary oncology team.
Donor lung procurement and preservation is critical for transplantation success. Unfortunately, the large variability in techniques impacts organ utilization rates outcomes. Compounding this variation, recent developments cold static new technological advances with machine perfusion have increased complexity of procedure. The objective American Association Thoracic Surgery (AATS) Clinical Practice Standards Committee (CPSC) expert panel was to make evidence-based recommendations best...
Abstract Uncontrolled donation after cardiac death is an appealing source of organs for lung transplantation. We compare early and long‐term outcomes transplantation with these donors a cohort transplants from brain at our institution. Retrospective analysis all transplantations was performed 2002 to 2012. collected variables regarding recipients, donors, recover transplant procedures, late complications, survival. included 292 38 uncontrolled death. Both groups were comparable except sex...
Post-lobectomy bronchopleural fistula is a rare complication of lung resection surgery, and proper management essential for its successful resolution. Most published papers deal with endoscopic surgical treatment. We report our experience conservative management. Data were collected by reviewing the clinical charts patients diagnosed post-lobectomy at University Hospitals Marqués de Valdecilla, Santander, Puerta Hierro, Majadahonda-Madrid, Spain, from June 2003 to December 2010....
Abstract Background Controlled donation after circulatory death (cDCD) has emerged as one of the main strategies for increasing organ donor pool. Because ischemic injury that follows withdrawal life-sustaining therapies, hearts from cDCD donors have not been considered transplantation until recently. The ex-situ perfusion directly procured used to allow continuous and assessment myocardial viability prior transplantation. Based on our experience with abdominal normothermic regional in cDCD,...
Controlled donation after circulatory death donors (cDCD) are becoming a frequent source of lungs grafts worldwide. Conversely, lung transplantations (LTx) from uncontrolled (uDCD) sporadically reported. We aimed to review our institutional experience using both uDCD and cDCD compare LTx brain (DBD). This is retrospective analysis all performed between January 2013 December 2019 in institution. Donor recipient characteristics were collected univariate, multivariate survival analyses carried...
Hyperacute rejection (HAR) is a well-known complication in renal and cardiac transplantation, but rare lung recipients. We present case of HAR the graft with fatal outcome male patient preformed class II anti-HLA antibodies.
Abstract OBJECTIVES We reviewed the incidence of coronavirus disease 2019 cases and postoperative outcomes patients who had thoracic surgery during beginning at highest point transmission in our community. METHODS retrospectively undergone elective from 12 February 2020 to 30 April were symptomatic or tested positive for severe acute respiratory syndrome 2 infection within 14 days after surgery, with a focus on their complications potential deaths. RESULTS Out 101 surgical procedures,...
Many patients with non-metastatic non-small cell lung cancer (NSCLC) are cured by surgery but part of them develop recurrence. Strategies needed to identify these relapses. Currently, there is no consensus on the follow-up schedule after curative resection for NSCLC. The objective this study analyze diagnostic capacity tests performed during surgery.We retrospectively reviewed 392 stage I-IIIA NSCLC who underwent surgery. Data were collected from diagnosed between January 1st, 2010 and...
Abstract OBJECTIVES The aim of this study was to compare the outcomes lung transplantations using grafts from donors aged over 70 years against those performed younger donors. METHODS This retrospective single-centre analysis includes transplants conducted at our institution January 2014 June 2022. Lung recipients were classified into 2 groups based on donor age (group A <70 years; group B ≥70 years). Variables regarding demographics, peri and postoperative survival included....
Chronic rejection or bronchiolitis obliterans (BO) is the main cause of morbidity and mortality 1 year after lung transplantation. The objective this study was to develop a reproducible animal model that mimics typical histological findings in human BO transplantation.We used 2 rat strains - Lewis (L) Wistar (W) transplanted segment donor trachea into each recipient. animals were divided groups: 1) recipient same strain (W-W), 2) different (L-W). From group, we created 4 subgroups examined...
Most transplant centres use donation after brain death (DBD) criteria to assess the quality of controlled circulatory (cDCD) lungs. However, research on relationship between DBD extended and cDCD lung transplantation outcomes is limited. We investigated using donor organs in transplantation, compared standard transplantation.A retrospective chart review consecutive referrals Hospital Universitario Puerta de Hierro-Majadahonda from June 2013 December 2019 was undertaken. Donors were divided...