A5101517898- COVID-19 Clinical Research Studies
- Blood groups and transfusion
- SARS-CoV-2 and COVID-19 Research
- Diabetes and associated disorders
- Long-Term Effects of COVID-19
- Parasitic Infections and Diagnostics
- Parasitic infections in humans and animals
- Immune responses and vaccinations
- Chronic Lymphocytic Leukemia Research
- Cancer Immunotherapy and Biomarkers
- Platelet Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Dialysis and Renal Disease Management
- Mast cells and histamine
- Family Support in Illness
- Neutropenia and Cancer Infections
- Genomic variations and chromosomal abnormalities
- Pregnancy and Medication Impact
- Health and Wellbeing Research
- Bladder and Urothelial Cancer Treatments
- Urologic and reproductive health conditions
- Cancer survivorship and care
- Complement system in diseases
- Blood donation and transfusion practices
- Multiple Myeloma Research and Treatments
Miami Children's Hospital
2025
Hospital Clínico Universitario de Valladolid
2020-2024
Hospital Universitario Infanta Leonor
2016-2024
Universidad de Valladolid
2021
NeuroDevelopment Center
2021
Hospital Rio Carrion
2019-2020
Centro Regional de Hemodonación
2016-2019
Turku Centre for Biotechnology
2019
University of Turku
2019
Centre de Recherche en Cancérologie de Lyon
2011
Pneumonia is the leading cause of hospital admission and mortality in coronavirus disease 2019 (COVID-19). We aimed to identify cytokines responsible for lung damage mortality. prospectively recruited 108 COVID-19 patients between March April 2020 divided them into four groups according severity respiratory symptoms. Twenty-eight healthy volunteers were used normalization results. Multiple showed statistically significant differences mild critical patients. High HGF levels associated with...
Abstract IMPORTANCE Prior studies have demonstrated the effectiveness of COVID-19 vaccines in children and adolescents. However, benefits vaccination these age groups with prior infection remain underexplored. OBJECTIVE To evaluate preventing reinfection various Omicron subvariants (BA.1/2, BA.4/5, XBB, later) among 5- to 17-year-olds SARS-CoV-2 infection. DESIGN A target trial emulation through nested designs distinct study periods. SETTING The utilized data from Research COVID Enhance...
Background Crimean-Congo haemorrhagic fever virus (CCHFV) is considered an emerging or even a probable re-emerging pathogen in southern Europe. Presence of this had been reported previously Spain 2010. Aim We aimed to evaluate the potential circulation CCHFV western with serosurvey asymptomatic adults (blood donors). Methods During 2017 and 2018, we conducted randomly selected blood donors from Spain. Three assays using specific IgG antibodies against were performed: VectoCrimea ELISA test,...
Introduction Coronavirus disease 2019 (COVID-19) affects the population unequally, with a greater impact on older and immunosuppressed people. Methods Hence, we performed prospective experimental cohort study to characterise effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in immune-compromised patients (older adults oncohaematologic patients), compared healthy counterparts, based deep characterisation circulating immune cell subsets. Results discussion...
Severe status of coronavirus disease 2019 (COVID-19) is extremely associated to cytokine release. Moreover, it has been suggested that blood group also with the prevalence and severity this disease. However, relationship between profile remains unclear in COVID-19 patients. In sense, we prospectively recruited 108 patients March April 2020 divided according ABO group. For analysis 45 cytokines, plasma samples were collected time admission hospital ward or intensive care unit at sixth day...
BACKGROUND Blood transfusion safety is based on reliable donor screening for transmissible infections such as the hepatitis C virus (HCV) infection. STUDY DESIGN AND METHODS A novel HCV core–specific antibody was assayed random single donations from 2007 first‐time blood donors who tested negative anti‐HCV and RNA routine screening. Sample collection broke code between ethical reasons. RESULTS Forty‐two (2.1%) displayed reactivity in test. The specificity of evaluated by a peptide inhibition...
<title>Abstract</title> <bold>Background</bold>: Pneumonia is the leading cause of hospital admission and mortality in coronavirus disease 2019 (COVID-19), attributed to a cytokine storm. The objective our study characterize this profile identify cytokines responsible for lung damage mortality.<bold>Methods: </bold>Plasma samples 108 prospectively recruited COVID-19 patients were collected between March and<sup> </sup>April 2020. Patients divided into four groups according severity...
The Community Transfusion Centre in Madrid currently processes whole blood using a conventional procedure (Compomat, Fresenius) followed by automated processing of buffy coats with the OrbiSac system (CaridianBCT). Atreus 3C (CaridianBCT) automates production red cells, plasma and an interim platelet unit from unit. Interim are pooled to produce transfusable In this study was evaluated compared routine method regards product quality operational value.Over 5-week period 810 units were...
Abstract Background: We already showed that lymphopenia (&lt;1000 lymphocytes/μl) or CD4+ T cell (&lt;450/μl) detected before initiation of chemotherapy are prognostic factors for toxicity and death metastatic breast cancer (MBC) patients. The goal the present study was to identify characteristics cells in these lymphopenic TCR diversity investigated tested as a factor overall survival (OS). Patients methods: ImmunTraCkeR® assay (ImmunID, Grenoble, France), which analyzes through...
ABSTRACT COVID-19 affects the population unequally with a higher impact on aged and immunosuppressed people. Hence, we assessed effect of SARS-CoV-2 vaccination in immune compromised patients (older adults oncohematologic patients), compared healthy counterparts. While acquired humoral cellular memory did not predict subsequent infection 18 months after full immunization, spectral computational cytometry revealed several subsets within CD8 + T-cells, B-cells, NK cells, monocytes CD45RA CCR7...
Although eosinophilia is a condition that appears frequently in clinical practice, its prevalence the general population Spain not well-defined. To determine of blood donors. Descriptive, cross-sectional study. Asymptomatic donors from Haemotherapy and Blood Donation Centre Castilla-León during January 2016 to December were included analysis. Of total 63,941 donors, 8616 (13.5%) presented with eosinophilia, 3839 (44.6%) had relative 4590 (53.3%) mild 185 (2.1%) moderate 2 (.02%) severe...