Shota Kawahara
A5063962571- Abdominal Trauma and Injuries
- Blood Coagulation and Thrombosis Mechanisms
- Trauma and Emergency Care Studies
- Neonatal Respiratory Health Research
- Trauma Management and Diagnosis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Urological Disorders and Treatments
- Hemophilia Treatment and Research
Hokkaido University Hospital
2022-2025
This study aimed to evaluate the effectiveness of combining initial hemoglobin levels with shock index for predicting need life-saving interventions (LSI) in pediatric patients blunt liver and spleen injuries (BLSI), specifically tailored different age groups. was a multicenter retrospective cohort BLSI Japan. The area under receiver operating characteristic curve (AUROC) were used assess predictive accuracy. included 1,370 patients. LSI required 59 247 (23.9%) aged 1 6 years, 100 402...
Abstract Background Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there no established consensus on target timing supplementation. We aimed to elucidate effects deficiency balance between coagulation activation inhibition using a thrombin generation assay as vitro global assay. Methods Samples were prepared by admixing commercially AT-deficient plasma < 1% activity pooled normal plasma. The each sample...