- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Thermal Regulation in Medicine
- Anesthesia and Sedative Agents
- Mechanical Circulatory Support Devices
- Esophageal and GI Pathology
- Injury Epidemiology and Prevention
- Traumatic Brain Injury Research
- Anesthesia and Pain Management
- Dysphagia Assessment and Management
- Healthcare Decision-Making and Restraints
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Emergency and Acute Care Studies
- Cardiac Structural Anomalies and Repair
- Trauma Management and Diagnosis
- Bone and Joint Diseases
- Spinal Hematomas and Complications
- Atrial Fibrillation Management and Outcomes
- Neuroscience of respiration and sleep
- Restraint-Related Deaths
Okayama University
1971-2025
Okayama Saiseikai General Hospital
2015-2025
Kibi International University
2024
Okayama University Hospital
2022
Nippon Medical School
1994-2009
Nippon Medical School Hospital
2005-2008
Chiba Hokusou Hospital
1995
In Brief BACKGROUND: Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect dexmedetomidine in patients NIV. METHODS: This was a prospective clinical investigation an intensive care unit. Dexmedetomidine infused 10 whom NIV difficult because agitation. RESULTS: Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 ± 0.94 −1.23 1.30, respectively. All successfully weaned from NIV, respiratory state not worsened. CONCLUSION:...
Objective: Sepsis often leads to heterogeneous symptoms of post-intensive care syndrome (PICS) composing physical, cognitive, and psychiatric disabilities, resulting in deteriorated quality life (QoL), with limited interventions. This study aimed identify phenotypes sepsis-associated PICS by function QoL at hospital discharge. Design: A prospective observational study. Setting: Twenty-one mixed ICUs. Patients: All consecutive adult patients between November 2020 April 2022, diagnosed sepsis...
Background The simplicity of the diagnostic definition acute respiratory distress syndrome (ARDS) has led to its diagnosis in patients with new-onset or exacerbation diffuse parenchymal lung diseases (DPLDs). This study investigated incidence DPLDs hypoxic failure (AHRF) who met Berlin definition. Methods Japan-based multicentre retrospective cohort included on mechanical ventilation For all participants, was made by pulmonology specialists DPLD and thoracic radiology (blinded clinical...
This study aimed to evaluate the effectiveness of combining initial hemoglobin levels with shock index for predicting need life-saving interventions (LSI) in pediatric patients blunt liver and spleen injuries (BLSI), specifically tailored different age groups. was a multicenter retrospective cohort BLSI Japan. The area under receiver operating characteristic curve (AUROC) were used assess predictive accuracy. included 1,370 patients. LSI required 59 247 (23.9%) aged 1 6 years, 100 402...
Abstract Background Carbon monoxide (CO), produced endogenously by heme oxygenase‐1, plays a crucial role in the immune system mitigating cellular damage under stress. However, significance of carboxyhemoglobin (COHb) levels after out‐of‐hospital cardiac arrest (OHCA) is not well understood. This study aimed to explore association between COHb at hospital arrival and within first 24 h post‐arrival with 30‐day mortality neurological outcomes patients who experienced OHCA. Methods...
Abstract Background Extracorporeal cardiopulmonary resuscitation (ECPR) is rapidly becoming a common treatment strategy for patients with refractory cardiac arrest. Despite its benefits, ECPR raises variety of ethical concerns when the discontinued. There little information about decision to withhold/withdraw life-sustaining therapy (WLST) out-of-hospital arrest (OHCA) after ECPR. Methods We conducted secondary analysis data from SAVE-J II study, retrospective, multicenter study in Japan....
Abstract Background The appropriateness of a restrictive transfusion strategy for those with active bleeding after traumatic injury remains uncertain. Given the association between tissue hypoxia and lactate levels, we hypothesized that optimal may differ based on levels. This post hoc analysis RESTRIC trial sought to investigate strategies patient outcomes initial Methods We performed trial, cluster-randomized, crossover, non-inferiority multicenter trials, comparing liberal red blood cell...
Abstract Background Limited data are available on organ donation practices and recipient outcomes, particularly when comparing donors who experienced cardiac arrest received extracorporeal cardiopulmonary resuscitation (ECPR) followed by veno-arterial membrane oxygenation (ECMO) decannulation, versus those without receiving ECPR. This study aims to explore outcomes post-ECPR enhance our understanding of the potential after arrest. Methods We conducted a nationwide retrospective cohort using...
BackgroundEmergency medical technicians (EMTs) may be subjected to emotional stress during patient treatment/transport. In Japan, dispatched EMTs must attempt resuscitation in all cases of out-of-hospital cardiac arrest (OHCA), including patients with "do not resuscitation" (DNAR) orders and whose families do support resuscitation. We described the characteristics, prevalence, outcomes OHCA/DNAR patients, aimed identify factors associated EMT when treating them.MethodsWe included OHCA...
In Brief Dexmedetomidine hydrochloride is a potent, highly selective α-2 adrenergic receptor agonist, broadly used as sedative drug in intensive care units. We describe the case of 59-yr-old patient who experienced fever caused by dexmedetomidine hydrochloride. The was transferred to unit with an abdominal aortic aneurysm rupture. After initiation sedation hydrochloride, he developed pyrexia more than 39°C. This symptom improved rapidly 7 h after stopping Other possible causes (such...
BackgroundIdentifying dysphagia as a potential complication of sepsis may improve swallowing function and survival while decreasing hospital length stay.ObjectivesOur goal was to determine the frequency in survivors on 7th day after admission, well their associated factors outcomes.MethodsThis single-centre, retrospective, observational study analysed data from admitted Okayama Saiseikai General Hospital 2018 2019. Participants with were assigned one two groups based presence or absence...
BackgroundGastric inflation caused by excessive ventilation is a common complication of cardiopulmonary resuscitation. Gastric may further compromise via increases in intrathoracic pressure, leading to decreased venous return and cardiac output, which impair out-of-hospital arrest (OHCA) outcomes. The purpose this study was measure the gastric volume OHCA patients using computed tomography (CT) scan images evaluate effect on spontaneous circulation (ROSC).MethodsIn single-center,...
To examine the change in vertebral bone mineral density (BMD) using abdominal computed tomography patients treated for sepsis.A single-center, retrospective, observational study was undertaken to evaluate BMD after critical care at Okayama Saiseikai General Hospital (Okayama, Japan) from January 2016 April 2018. Sepsis defined as an absolute increase of ≥2 Sequential Organ Failure Assessment score intensive unit or high unit. Bone evaluated Hounsfield units (HU) by tomography. Patients were...
Abstract Background Evidence indicates frailty before intensive care unit (ICU) admission leads to poor outcomes. However, it is unclear whether quality of life (QOL) and activities daily living (ADL) for survivors critical illness admitted the ICU via emergency department remain consistent or deteriorate in long-term compared baseline. This study aimed evaluate QOL/ADL outcomes these patients, categorized by presence absence according Clinical Frailty Scale (CFS) score, as well explore...