Tsuyoshi Nojima

ORCID: 0000-0003-0768-0179
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About
Contact & Profiles
Research Areas
  • Cardiac Arrest and Resuscitation
  • Trauma and Emergency Care Studies
  • Trauma Management and Diagnosis
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Hydrogen's biological and therapeutic effects
  • Heme Oxygenase-1 and Carbon Monoxide
  • Injury Epidemiology and Prevention
  • Neonatal Health and Biochemistry
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Anesthesia and Neurotoxicity Research
  • Traumatic Brain Injury Research
  • Organ Transplantation Techniques and Outcomes
  • Emergency and Acute Care Studies
  • Thermal Regulation in Medicine
  • Sepsis Diagnosis and Treatment
  • Abdominal Trauma and Injuries
  • Cannabis and Cannabinoid Research
  • Intensive Care Unit Cognitive Disorders
  • Abdominal vascular conditions and treatments
  • Glycogen Storage Diseases and Myoclonus
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Pelvic and Acetabular Injuries
  • Suicide and Self-Harm Studies
  • Mechanical Circulatory Support Devices
  • Cardiovascular Syncope and Autonomic Disorders

Okayama University
1999-2025

Japanese Red Cross Kobe Hospital
2021

Red Cross Hospital
2021

Okayama Rosai Hospital
2021

Okayama University Hospital
2021

University of Kochi
2015-2016

Kanazawa Medical University
2002

Abstract Background Carbon monoxide (CO), produced endogenously by heme oxygenase‐1, plays a crucial role in the immune system mitigating cellular damage under stress. However, significance of carboxyhemoglobin (COHb) levels after out‐of‐hospital cardiac arrest (OHCA) is not well understood. This study aimed to explore association between COHb at hospital arrival and within first 24 h post‐arrival with 30‐day mortality neurological outcomes patients who experienced OHCA. Methods...

10.1002/ams2.70053 article EN cc-by-nc-nd Acute Medicine & Surgery 2025-01-01

Abstract Background Limited data are available on organ donation practices and recipient outcomes, particularly when comparing donors who experienced cardiac arrest received extracorporeal cardiopulmonary resuscitation (ECPR) followed by veno-arterial membrane oxygenation (ECMO) decannulation, versus those without receiving ECPR. This study aims to explore outcomes post-ECPR enhance our understanding of the potential after arrest. Methods We conducted a nationwide retrospective cohort using...

10.1186/s13054-024-04949-5 article EN cc-by Critical Care 2024-05-13

Hypothalamic hamartoma is a non-neoplastic tumor consisting of ectopic brain tissue derived from the hypothalamus [1]. Patients with hypothalamic sometimes present gelastic seizure, precocious puberty, and behavioral disorder [2] [3]. The neuroradiological diagnosis based on following criteria: an isointense lesion relative to normal gray matter T1-weighted magnetic resonance (MR) images, pedunculated or sessile attachment hypothalamus; lack contrast enhancement MR images computed...

10.1055/s-2002-36196 article EN min - Minimally Invasive Neurosurgery 2002-12-01

Thyroid storm is a potentially fatal intensification of thyrotoxicosis normally marked by tachycardia, hyperthermia, impaired mental status, and severe agitation. It can be initiated numerous causes. Failure to promptly diagnose the condition may lead high mortality. Early diagnosis treatment thyroid are essential prevent further life-threatening complications. A 10-year-old girl was admitted our emergency center for intensive care. The patient presented tachypnea with stridor, paradoxical...

10.1016/j.rmcr.2020.101182 article EN cc-by-nc-nd Respiratory Medicine Case Reports 2020-01-01

Aim Although uncommon, medical emergencies arise in general dental practice. Inadequate data on their severity and frequency makes targeting education for practitioners difficult. This also planning unexpected events challenging collaborating with emergency physicians burdensome. We aimed to clarify the incidence characteristics of a outpatient department’s emergencies. Methods single‐center, retrospective, observational study was undertaken patients who visited department Okayama University...

10.1002/ams2.651 article EN cc-by-nc-nd Acute Medicine & Surgery 2021-01-01

Acute respiratory distress syndrome, which is caused by acute lung injury, a destructive disorder systemic inflammatory response. Persistent inflammation results in irreversible alveolar fibrosis. Because hydrogen gas possesses anti-inflammatory properties, we hypothesized that daily repeated inhalation of could suppress persistent inducing functional changes macrophages, and consequently inhibit fibrosis during late-phase injury.To test this hypothesis, injury was induced mice intratracheal...

10.1186/s12890-021-01712-2 article EN cc-by BMC Pulmonary Medicine 2021-10-31

Aim It has been widely reported that pre‐injury use of anticoagulant and antiplatelet agents can affect traumatic brain injury the associated risk mortality, however, effect these on non‐head site‐related blood loss remains unclear. Therefore, we investigated effects transfusion amount need for massive in elderly patients with severe trauma. Methods We retrospectively reviewed a cohort trauma (age, ≥65 years; Injury Severity Score, ≥16) between S eptember 2006 M arch 2014. The selected were...

10.1002/ams2.152 article EN other-oa Acute Medicine & Surgery 2015-08-27

Lung contusion caused by blunt chest trauma evokes a severe inflammatory reaction in the pulmonary parenchyma that may be associated with acute respiratory distress syndrome. Although hydrogen gas has antioxidant and anti-inflammatory effects is protective against multiple types of lung injury at safe concentrations, inhaled on have not been previously investigated. Therefore, using mouse model, we tested hypothesis inhalation after would reduce inflammation contusion.Inbred male C57BL/6...

10.1016/j.surg.2023.04.029 article EN cc-by-nc-nd Surgery 2023-05-18

Abstract Prolonged intestinal cold storage causes considerable mucosal breakdown, which could bolster bacterial translocation and cause life‐threatening infection for the transplant recipient. The intestine has an intraluminal compartment, be a target intervention, but not yet been fully investigated. Hydrogen gas exerts organ protection used recently in several clinical basic research studies on topics including transplantation. In this study, we aimed to investigate cytoprotective efficacy...

10.1111/petr.13848 article EN Pediatric Transplantation 2020-09-30

The ginkgo tree is a well-known, highly adaptable urban plant. Ginkgo nuts are the product of tree. Interior cooked and served in Asian countries; however, potential toxicity gingko not commonly known. Herein, we report 48-year-old male patient experiencing acute convulsions presumably due to overconsumption nuts. was transferred our department after several episodes generalized tonicclonic seizures lasting approximately 30 seconds each starting one hour before visit. also complained...

10.1155/2020/5072954 article EN cc-by Case Reports in Emergency Medicine 2020-01-28

Burning mouth syndrome (BMS) is characterized as the sensation of burning in tongue or any other area oral mucosa without a medical dental cause. BMS's pathophysiology poorly understood and may be caused by its association with various factors, particularly antihypertensive psychotropic medicines. Although BMS relatively common intraoral disorder field, emergency physicians rarely recognize it. We report 53-year-old Japanese woman who presented to our ED three-week history strange taste...

10.7759/cureus.11376 article EN Cureus 2020-11-08

Abstract Background Patients with traumatic cardiac arrest (TCA) are known to have poor prognoses. In 2003, the joint committee of National Association EMS Physicians and American College Surgeons Committee on Trauma proposed stopping unsuccessful cardiopulmonary resuscitation (CPR) sustained for > 15 min after TCA. However, in 2013, a specific time-limit terminating was dropped, due lack conclusive studies or data. We aimed define association between emergency medical services transport...

10.1186/s12873-021-00499-z article EN cc-by BMC Emergency Medicine 2021-09-16

The protective effects of carbon monoxide (CO) against ischemia/reperfusion (IR) injury during organ transplantation have been extensively investigated. Likewise, CO-releasing molecules (CORMs) are known to exert a variety pharmacological activities via liberation controlled amounts CO in organs. Therefore, we hypothesized that intraluminal administration water-soluble CORM-3 cold storage intestinal grafts would provide IR injury.Orthotopic syngeneic was performed Lewis rats following 6 h...

10.1097/tp.0000000000004007 article EN cc-by-nc-nd Transplantation 2021-12-27

Hamman's syndrome is an uncommon clinical entity characterized by idiopathic spontaneous pneumomediastinum as a result of sudden increase in intra-alveolar pressure. It can be triggered repeated vomiting or Kussmaul breathing associated with diabetic ketoacidosis (DKA). Careful attention to this particular condition needed avoid under-diagnosis and provide optimal management. Herein, we report case 18-year-old man complaining chest discomfort progressive weight loss, ultimately diagnosed...

10.22037/aaem.v10i1.1709 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2022-01-01

Blunt neck trauma patients can suffer from an airway emergency and are necessary to careful observation. A 79-year-old man under anticoagulation therapy presented our hospital three hours after a fall. Shortly arrival, he developed dyspnea. Oral intubation was attempted, but with no success; therefore, tracheotomy performed. Contrast-enhanced computed tomography (CT) subsequent angiography revealed active bleeding branch of the right ascending cervical artery. Subsequently, thyrocervical...

10.1016/j.ijscr.2020.11.007 article EN International Journal of Surgery Case Reports 2020-01-01
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