Junko Ishihara

ORCID: 0000-0002-9516-5646
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About
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Research Areas
  • Nutritional Studies and Diet
  • Obesity, Physical Activity, Diet
  • Nutrition, Health and Food Behavior
  • Consumer Attitudes and Food Labeling
  • Diet and metabolism studies
  • Sodium Intake and Health
  • Potato Plant Research
  • Folate and B Vitamins Research
  • Antioxidant Activity and Oxidative Stress
  • Phytoestrogen effects and research
  • Cancer Risks and Factors
  • Diet, Metabolism, and Disease
  • Nutrition and Health in Aging
  • Plant Pathogens and Resistance
  • Fatty Acid Research and Health
  • Genomics, phytochemicals, and oxidative stress
  • Nutrition, Genetics, and Disease
  • Colorectal Cancer Screening and Detection
  • Tea Polyphenols and Effects
  • Carcinogens and Genotoxicity Assessment
  • Liver Disease Diagnosis and Treatment
  • Bladder and Urothelial Cancer Treatments
  • Trauma and Emergency Care Studies
  • Glutathione Transferases and Polymorphisms
  • Ginkgo biloba and Cashew Applications

Azabu University
2017-2025

Centre International de Recherche sur le Cancer
2023

Nara Women's University
2022-2023

Cambridge University Press
2016-2023

New York University Press
2016-2023

National Cancer Centre Japan
2003-2019

Printed Electronics (United Kingdom)
2019

Sagami Women's University
2011-2018

University of Kochi
2011-2016

University of Southampton
2016

Reverse-phase high-performance liquid chromatography and photodiode array detection were used to analyze the microbial quinones of influent sewage activated sludge in a treatment plant. Significant differences quinone patterns noted between sludge. Unlike sludge, had low ratios menaquinones ubiquinones, contained menaquinone-6 as most abundant menaquinone negligible amounts partially hydrogenated menaquinones. A analysis revealed that also considerable plastoquinones vitamin K1, both which...

10.2323/jgam.42.457 article EN The Journal of General and Applied Microbiology 1996-01-01

Background— Once- or twice-weekly consumption of fish (or a small amount intake) reduces the risk coronary heart disease and sudden cardiac death in Western countries. It is uncertain whether high frequency large intake, as case Japan, further risk. Methods Results— To examine an association between intake n3 polyunsaturated fatty acids disease, total 41 578 Japanese men women aged 40 to 59 years who were free prior diagnosis cardiovascular cancer completed food questionnaire followed up...

10.1161/circulationaha.105.581355 article EN Circulation 2006-01-10

Longitudinal epidemiological studies require both the periodic update of intake information via repeated dietary survey and minimization subject burden in responding to questionnaires. We developed a 66-item Food Frequency Questionnaire (short-FFQ) for Japan Public Health Center-based prospective Study Next Generation (JPHC-NEXT) follow-up using major foods from FFQ original JPHC Study. For JPHC-NEXT baseline survey, we used larger 172-item (long-FFQ), which was also derived JPHC-FFQ....

10.2188/jea.je20150064 article EN cc-by Journal of Epidemiology 2016-01-01

Epidemiological evidence regarding the long-term effects of higher dietary protein intake on mortality outcomes in general population is not clear.To evaluate associations between animal and plant all-cause cause-specific mortality.This prospective cohort study included 70 696 participants Japan Public Health Center-based Prospective Cohort who were aged 45 to 74 years had no history cancer, cerebrovascular disease, or ischemic heart disease at baseline. Data collected from January 1, 1995,...

10.1001/jamainternmed.2019.2806 article EN JAMA Internal Medicine 2019-08-26

Background— Soy and isoflavones have been proposed to reduce the risk of cardiovascular factors, but their potential as preventatives for disease remains uncertain. We investigated association soy isoflavone intake with cerebral myocardial infarctions (CI MI). Methods Results— To examine CI MI, we studied 40 462 Japanese (40 59 years old, without or cancer at baseline). They completed a food-frequency questionnaire (1990–1992) received follow-up 2002. After 503 998 person-years follow-up,...

10.1161/circulationaha.106.683755 article EN Circulation 2007-11-20

Few studies have investigated the effects of fruit and vegetables on risk both cancer cardiovascular disease (CVD). The authors examined associations between vegetable consumption total CVD in same Japanese population. During 1995-1998, a validated food frequency questionnaire was administered nine areas to 77,891 men women aged 45-74 years. as many 459,320 person-years follow-up until end 2002, 3,230 cases 1,386 were identified. Higher fruit, but not vegetables, associated with...

10.1093/aje/kwm263 article EN American Journal of Epidemiology 2007-10-10

Few prospective studies have examined the impact of both green tea and coffee consumption on strokes. We investigated association combination those with stroke incidence in a general population.We studied 82 369 Japanese (aged 45-74 years; without cardiovascular disease [CVD] or cancer 1995 1998 for Cohort I II, respectively) who received 13 years mean follow-up through end 2007. Green was assessed by self-administered food frequency questionnaire at baseline.In 1 066 718 person-years...

10.1161/strokeaha.111.677500 article EN Stroke 2013-03-15

Objective A meta-analysis showed an inverse association of a prudent/healthy dietary pattern with all-cause mortality and no western/unhealthy pattern. However, the distinctive patterns Japanese population remains unclear. We prospectively investigated between all-cause, cancer, cardiovascular disease among adults. Methods Participants were 36,737 men 44,983 women aged 45–74 years who participated in second survey Japan Public Health Center-based Prospective Study (1995–1998) had history...

10.1371/journal.pone.0174848 article EN cc-by PLoS ONE 2017-04-26

The objective of this study was to evaluate the validity and reproducibility a self-administered food frequency questionnaire (FFQ) estimate nutrient intake in subjects Japan Public Health Center-based prospective Study on Cancer Cardiovascular Diseases (JPHC Cohort II). FFQ originally developed JPHC I. A total 392 sub-jects were recruited from entire cohort participants 6 areas II voluntary basis. completed used for 5-year follow-up survey twice at approximately 1-year interval. Seven-day...

10.2188/jea.13.1sup_134 article EN cc-by Journal of Epidemiology 2003-01-01

Respiratory quinones were used as biomarkers to study bacterial community structures in activated sludge reactors for enhanced biological phosphate removal (EBPR). We compared the quinone profiles of EBPR sludges and standard sludges, natural sewage synthetic sewage, plant scale laboratory systems. Ubiquinone (Q) menaquinone (MK) components detected all tested at molar MK/Q ratios 0.455 0.981. The differences much larger when we different wastewater (i.e., raw sewage) than from processes or...

10.1128/aem.64.3.992-998.1998 article EN Applied and Environmental Microbiology 1998-03-01

Although it has been hypothesized that a high intake of dietary calcium may reduce the risk cardiovascular disease (CVD), no prospective studies have conducted to examine specific association between and incidence stroke or coronary heart among Japanese with low average intake.To investigate CVD, total 41 526 men women age 40 59 years without history CVD cancer who had completed food consumption frequency questionnaire were enrolled in this study. The subjects followed up from 1990 1992...

10.1161/strokeaha.107.512236 article EN Stroke 2008-07-18

Abstract Background Several studies have determined that dietary intake of B vitamins may be associated with breast cancer risk as a result interactions between 5,10-methylenetetrahydrofolate reductase (MTHFR) and methionine synthase ( MTR ) in the one-carbon metabolism pathway. However, association vitamin Brazilian women particular has not yet been investigated. Methods A case-control study was conducted São Paulo, Brazil, 458 age-matched pairs women. Energy-adjusted intakes folate, 6 , 12...

10.1186/1471-2407-9-122 article EN cc-by BMC Cancer 2009-04-24

Background: Analysis of dietary pattern is increasingly popular in nutritional epidemiology. However, few studies have examined the validity and reproducibility patterns. We assessed patterns identified by a food frequency questionnaire (FFQ) used 5-year follow-up survey Japan Public Health Center-Based Prospective Study (JPHC Study).Methods: The participants were subsample (244 men 254 women) from JPHC Study. Principal component analysis was to identify 28- or 14-day records 2 FFQs. To...

10.2188/jea.je20110087 article EN cc-by Journal of Epidemiology 2012-01-01

AimsAlthough dietary saturated fatty acids (SFA) are considered atherogenic, associations between SFAs intake and stroke coronary heart disease still debated. We sought to test the hypothesis that SFA is associated inversely with risk of its subtypes positively among Japanese, whose average lower than Westerners.

10.1093/eurheartj/eht043 article EN European Heart Journal 2013-02-12

In this section we described the structure of self-administered semiquantitative food frequency questionnaire used in 5-year follow-up survey JPHC study, computation algorithms, and area-based mean intakes nutrients groups subjects validation study. The FFQ consists five sections: 1) questions for rice miso (fermented soybean paste)-soup, 2) those alcoholic beverages, 3) vitamin supplements, 4) foods 5) on dietary cooking behaviors. From questions, by were computed. Although most them...

10.2188/jea.13.1sup_13 article EN cc-by Journal of Epidemiology 2003-01-01

Background The associations between supplement use and certain demographics, lifestyles, health characteristics, dietary intakes have not been studied in a large population non-Western societies. objective of our study was to investigate the association intake population-based cohort Japan. Methods Subjects were 78 531 participants (45–74 years) who completed self-administered questionnaire 1995 or 1998 5-year follow-up survey by Japan Public Health Center-based prospective Study on cancer...

10.1093/ije/dyg091 article EN International Journal of Epidemiology 2003-08-01

BACKGROUND: Revision of the national nutrient database in 2000 had a strong impact on absolute level estimated intake dietary assessments. However, whether it influenced ranking individuals by intake, more important function epidemiologic studies, has not been investigated. Here, we investigated effect this revision validity food frequency questionnaire (FFQ) used to estimate Japan Public Health Center-based prospective Study (JPHC Study).METHODS: Subjects were subsample JPHC who volunteered...

10.2188/jea.16.107 article EN cc-by Journal of Epidemiology 2006-01-01

Abstract Abstract: We conducted a case-control study to investigate the association of nutrient intake involved in one-carbon pathway folate for DNA methylation and synthesis related enzyme genetic polymorphisms with colorectal cancer. Cases were 107 patients newly diagnosed Controls 224 subjects matched cases by sex, age, residential area. Nutrient was assessed self-administered, semiquantitative food-frequency questionnaire. Four polymorphisms—MTHFR C677T A1298C, MTRR A66G, ALDH2...

10.1207/s15327914nc5301_5 article EN Nutrition and Cancer 2005-09-01

10.3945/ajcn.2008.26195 article EN publisher-specific-oa American Journal of Clinical Nutrition 2008-12-01
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