A self-administered diet history questionnaire has been developed for the use in health education Japan. The relative validity of test-version was examined using 3-day record (DR) as a reference method. Subjects were mildly hypercholesterolemic 47 women aged 38-69 years living Hikone, provided close estimation nutrients compared to DR (mean 3-days), 1-25% differences between two methods observed total energy and 17 examined. general smaller macronutrients, 1-3%, than micronutrients, 1-25%....

Although isoflavones, such as those found in soy, have been shown to inhibit breast cancer laboratory studies, associations between consumption of isoflavone-containing foods and risk inconsistent epidemiologic studies. We evaluated the relationship isoflavone among women Japan Public Health Center-Based Prospective Study on Cancer Cardiovascular Diseases (JPHC Study).In January 1990, 21 852 Japanese female residents (aged 40-59 years) from four public health center areas completed a...

To evaluate the role of dietary factors in etiology inflammatory bowel disease (IBD), we conducted a multicenter hospital-based case-control study Japanese population. Cases were IBD patients aged 15 to 34 years [ulcerative colitis (UC) 111 patients; Crohn's (CD) 128 patients] within 3 after diagnosis 13 hospitals. One control subject was recruited for each case who matched sex, age, and hospital. A semiquantitative food frequency questionnaire used estimate preillness intakes groups...

Although several self-administered dietary assessment questionnaires have been developed for Japanese subjects, they seldom validated with objective mea-sures. We a recently self administered diet history questionnaire (DHQ) fatty acids in serum phospholipid fractions, alpha- and beta-carotenes alpha-toco-pherol as gold standard using 86 university workers (42 men 44 women, age-range=24-67 y). The age-adjusted Pearson partial correlation coefficients between the intakes of marine origin n-3...

Background and Purpose— The impact of light-to-moderate alcohol consumption on risk stroke has not been well examined in a single study, although the effect is hypothesized to differ among subtypes from meta-analyses. Methods— A total 19 544 men aged 40 59 years living communities were followed-up 1990 1992 end 2001 Japan Public Health Center-based Prospective Study Cancer Cardiovascular Disease (JPHC Study). Results— After 214 504 person-years follow-up, 694 incident strokes documented,...

Mild metabolic acidosis, which can be caused by diet, may adversely affect cardiometabolic risk factors, possibly increasing cortisol production. Methodologies for estimating diet-induced acid-base load using dietary-intake information have been established. To our knowledge, however, the possible association between dietary and factors has not investigated. We cross-sectionally examined associations in a free-living population. The subjects were 1136 female Japanese dietetic students aged...

To examine the association between alcohol consumption and mortality in Japan, where lifestyle differ substantially from Western countries, a population-based prospective study was conducted four public health center areas as part of Japan Public Health Center-based on cancer cardiovascular disease (JPHC). After excluding subjects with self-reported serious diseases at baseline, 19,231 men aged 40–59 years who reported their intake were followed 1990 through 1996, 548 deaths documented. The...

We examined the validity of food intake measurements from a self-administered frequency questionnaire (FFQ) used in 5-year follow-up survey JPHC study using 28- or 14-day dietary records (DR) as gold standard. The median (range) correlation coefficients between 19-food group measured by FFQ and DR were 0.42 (0.13-0.76) for men 0.41 (0.02-0.75) women. energy-adjusted was 0.38 (0.08-0.76) 0.32 (0.06-0.66) mean percentage classification into same categories two methods 30% 31 % Only 2% 3% women...

The objective of this study was to evaluate the validity and reproducibility a self-administered food frequency questionnaire (FFQ) estimate nutrient intake in subjects Japan Public Health Center-based prospective Study on Cancer Cardiovascular Diseases (JPHC Cohort II). FFQ originally developed JPHC I. A total 392 sub-jects were recruited from entire cohort participants 6 areas II voluntary basis. completed used for 5-year follow-up survey twice at approximately 1-year interval. Seven-day...

Abstract The association between vegetables and fruit consumption gastric cancer risk was investigated in a population‐based prospective study 4 public health center areas Japan. Dietary other exposure data were obtained 1990 from cohort of 19,304 men 20,689 women with self‐administered questionnaire. After 10 years follow‐up, total 404 cases documented among them. adjustment for age, gender, potential confounding factors after exclusion the diagnosed first second follow‐up years, relative...

Abstract In order to update the findings of relative risk associated with cigarette smoking for lung cancer by histologic type in Japan, data from a population‐based cohort study 91,738 men and women were analyzed. During 1990–1999, 422 incident cases identified. The all current smokers versus non‐smokers was 4.5 [95% confidence interval (CI): 3.0–6.8] 4.2 (95% CI: 2.4–7.2), women, respectively. When divided type, squamous cell carcinoma small 12.7 4.7–34.7) 17.5 4.9–62.1), while...

Abstract The effect of cigarette smoking or alcohol consumption on the risk gastric cancer has not been clarified. We investigated this relationship, considering anatomic subsite and histologic type cancer. A total 19,657 men (aged 40–59 years at baseline), who responded to baseline questionnaire reported no serious illness that time, were followed for 10 years, from January 1990 December 1999. Gastric was confirmed histologically in 293 men. Smoking associated with an increased...

We examined sex-specific relationships of smoking with risk total stroke and subtypes in Asian populations because the limited data available.A 19,782 men 21,500 women aged 40 to 59 years who were free prior diagnosis stroke, coronary heart disease, or cancer reported their status followed Japan Public Health Center-based Prospective Study on Cancer Cardiovascular Disease (JPHC Study) from 1990 1992 end 2001.During a 461,761 person-year follow-up, 702 strokes documented among men, which 619...

We examined the validity and reproducibility of a 44-item food frequency questionnaire used in baseline survey Japan Public Health Center-Based Prospective Study Cohort I conducted February 1990. Subjects were 94 men 107 women selected on voluntary basis among respondents to survey. Four or five years after survey, they provided four 7-day diet records during 1-year period, then responded same second time. The median (range) for energy-adjusted correlation coefficients between 30 nutrients...

A sex- and age-matched case-control study was carried out.To facilitate early prediction, prevention, treatment of ossification the posterior longitudinal ligament spine, authors analyzed histories past illness, body mass indexes, pliableness by nature, adjusted for other factors considered to be risk factors.The cause spine has not yet been elucidated in detail, although many possible causative have suggested, including gender, diabetes mellitus, trauma, hormonal imbalance, dietary habits.A...

We examined 13-year trends in dietary patterns, using data from the National Health and Nutrition Survey, Japan 2003–2015. In repeated, independent cross-sectional studies, intake was assessed with a one-day weighed record 88,527 Japanese adults aged ≥20 years. Using principal component analysis based on daily consumption of 31 food groups, we identified three “plant fish”, “bread dairy”, “animal oil” patterns. whole sample, fish” pattern score decreased while dairy” scores increased. The...

We have already reported invasive ductal carcinomas (IDCs) with fibrotic focus (FF) to be associated significantly poorer survival than IDCs without FF. The purpose of this study was prospectively investigate the effect presence FF on outcomes 439 patients confirm prognostic significance FF, by multivariate analysis, employing Cox proportional hazard regression model, as compared well-known clinicopathological parameters. also precisely evaluated from viewpoint characteristics. present...

The prognosis of pancreatic carcinoma is generally very poor and difficult to predict. aim this study was quantitate with the onset symptoms.Survival curves clinicopathological findings 209 patients cancer admitted our hospital between 1992 1998 were retrospectively analyzed reference their symptoms (eg, abdominal pain, back jaundice, general fatigue, nausea) tumor location head, body, tail). interval from patient's first medical treatment laboratory data also reviewed. Univariate...

In order to investigate the associations between dietary patterns and risk of colorectal cancer by subsite in Japan, baseline data from a population-based cohort study 20,300 men 21,812 women were analyzed. We conducted factor analysis identified 3 major patterns, "healthy," "traditional" "Western," calculated scores each pattern for individuals. During 10 years follow-up, 370 cases identified. found positive association traditional colon [rate ratio highest quartile (RR) = 2.06; 95% CI...