A5012451214- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Intensive Care Unit Cognitive Disorders
- Geriatric Care and Nursing Homes
- Anesthesia and Sedative Agents
- Migration, Aging, and Tourism Studies
- Health disparities and outcomes
- Anesthesia and Neurotoxicity Research
- Dementia and Cognitive Impairment Research
MRC Unit for Lifelong Health and Ageing
2021-2023
University College London
2021-2023
Medical Research Council
2022-2023
University of London
2022
There is an unmet public health need to understand better the relationship between baseline cognitive function, occurrence and severity of delirium, subsequent decline. Our aim was quantify cognition delirium follow-up impairment.
BackgroundPrevious population-based, longitudinal studies have shown that delirium is associated with an increased risk of dementia and cognitive decline. However, the underlying biological mechanisms are largely unknown. We aimed to assess effects on both trajectories any neuronal injury, measured via neurofilament light chain (NfL).MethodsIn this analysis a prospective, 2-year follow-up, cohort study participants aged 65 years or older living in Sandefjord municipality, Norway, we included...
Abstract Introduction Life-space and frailty are closely linked to health-related quality of life understanding their inter-relationship could indicate potential intervention targets for improving life. We set out examine the relationship between life-space relative impact on measures. Methods Using cross-sectional data from a population-representative cohort people aged ≥ 70 years, we assessed with EuroQol Health Index tool (5-levels) (EQ-5D-5L). also undertook assessment derived index....
Abstract Introduction Frailty and socioeconomic position (SEP) are well‐established determinants of health. However, we know less about the contributions frailty SEP in older adults, especially acute settings. We set out to answer how might influence health outcomes people, comparing a population sample patients managed by speciality service. Methods used Delirium Population Health Informatics Cohort, 1510 individuals aged ≥70 years from London Borough Camden 1750 patients. was determined...
Introduction: Life-space and frailty are closely linked to health-related quality of life understanding their inter-relationship could indicate potential intervention targets for improving life. We set out quantify the relationship between life-space, relative impact on measures.Methods: Using cross-sectional data from a population-representative cohort people aged ≥70 years, we assessed with EuroQol Health Index tool (5-levels) (EQ-5D-5L). also undertook life-space assessment derived index....