A5080878960- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Photoreceptor and optogenetics research
- Acoustic Wave Phenomena Research
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Biochemical Analysis and Sensing Techniques
Yale University
2025
University of Wisconsin–Madison
2022
Wisconsin Division of Public Health
2019
Synchronous neuronal activity is a hallmark of the developing mouse primary somatosensory cortex. While patterns synchronous in cortical layer 2/3 have been well described, source robust still unknown. Using novel microprism preparation and vivo 2-photon imaging neonatal mice, we show that organized barrel columns across layers. Monosynaptic rabies tracing slice electrophysiology experiments reveal pyramidal neurons receive significant 5 inputs during first postnatal week, silencing synaptic...
T-stellate cells in the ventral cochlear nucleus (VCN) form an ascending pathway that conveys spectral information from cochlea to brainstem nuclei, inferior colliculi, and thalamus. The tonotopic array of enhances encoding peaks relative their auditory nerve fiber inputs. alignment local collaterals cell dendrites within isofrequency lamina suggests make connections which they reside. Recordings pairs mice both sexes revealed firing presynaptic evoked responses postsynaptic when was paired...
Abstract T‐stellate cells in the ventral cochlear nucleus (VCN) are known to have local axon collaterals that terminate vicinity of their dendrites and cell bodies within same isofrequency lamina parallel with auditory nerve fibers innervate them. Excitatory synaptic connections between stellate an hypothesized be involved nitric oxide‐mediated upregulation responses input. This could serve as a mechanism variable gain control enhancement vowel spectral peaks. Previous studies provided...