Zeynep ÇELİK

ORCID: 0000-0002-9667-5728
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About
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Research Areas
  • Microbial infections and disease research
  • Veterinary Oncology Research
  • Veterinary medicine and infectious diseases
  • Animal Virus Infections Studies
  • Helicobacter pylori-related gastroenterology studies
  • Drug-Induced Hepatotoxicity and Protection
  • Essential Oils and Antimicrobial Activity
  • PI3K/AKT/mTOR signaling in cancer
  • Mesenchymal stem cell research
  • Toxin Mechanisms and Immunotoxins
  • Multiple Myeloma Research and Treatments
  • Tracheal and airway disorders
  • Reproductive Biology and Fertility
  • Renal and related cancers
  • Colorectal Cancer Treatments and Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Acute Lymphoblastic Leukemia research
  • Bacterial Infections and Vaccines
  • Coccidia and coccidiosis research
  • Wound Healing and Treatments
  • Neuroendocrine Tumor Research Advances
  • Veterinary Medicine and Surgery
  • Mycobacterium research and diagnosis
  • Pharmacological Effects of Natural Compounds
  • Neuroblastoma Research and Treatments

Selçuk University
2020-2024

Pancur Kasih Association
2023

University of Veterinary Science
2023

Weatherford College
2022

The aim of this study is to evaluate the treatment efficacy Platelet–Rich Plasma (PRP), silver sulfadiazine, and Wharton Jelly Mesenchymal Stem Cell–Derived Conditioned Medium (WJ–MSC–CM) on burn wounds using a rat model. included four groups, each with 16 rats, groups were further divided into two subgroups (n=8) for 7th 14th days process. Group 1 received no after burn. 2 PRP (Platelet–Rich Plasma) first day 3 was treated sulfadiazine 4 WJ–MSC–CM In current study, expression Caspase–3,...

10.52973/rcfcv-e35517 article EN cc-by-nc-sa Revista Científica de la Facultad de Ciencias Veterinarias 2025-03-03

Gentamicin, an aminoglycoside antibiotic, is nowadays widely used in the treatment of gram-negative microorganisms. The antimicrobial, anti-inflammatory, and antioxidant activities eucalyptol, a type saturated monoterpene, have been reported many studies. aim this study was to examine possible effects eucalyptol on gentamicin-induced renal toxicity. A total 32 rats were divided into 4 groups; Control (C), Eucalyptol (EUC), Gentamicin (GEN), + (GEN EUC). In order induce toxicity, 100 mg/kg...

10.1080/15376516.2023.2297234 article EN Toxicology Mechanisms and Methods 2023-12-20

Purpose: To evaluate the effect of a combination Tarantula cubensis alcohol extract (TCAE) and capecitabine (CAP) in treatment azoxymethane (AOM)-induced colorectal cancer (CRC). 
 Methods: Forty-two Wistar albino rats were divided into 7 groups with 6 each group. The consisted Control (C), Control+TCAE (C-TCAE), Control+CAP (C-CAP), Cancer control (CC), Cancer+TCAE (CC-TCAE), Cancer+CAP (CC-CAP) Cancer+CAP+TCAE (CC-CAP+TCAE). induce CRC, AOM (15 mg/kg) was administered to...

10.4314/tjpr.v23i2.8 article EN cc-by Tropical Journal of Pharmaceutical Research 2024-03-12

Helicobacter species such as H. heilmannii, pylori, felis, bizzozeronii and salomonis have been identified in cats dogs, research suggesting that these may be zoonotic agents has studied intensified recent years. The aim of this study was to reveal the presence, comparing histopathological findings Real-time PCR results pylori stomach liver tissues taken during necropsies owned, stray or shelter dogs. material consisted from 35 dogs died for different reasons were brought necropsy. DNA...

10.52973/rcfcv-e33214 article EN cc-by-nc-sa Revista Científica de la Facultad de Ciencias Veterinarias 2023-02-07

This study examines the impact of varying doses Doxorubicin (DOX) on body weight in rats, with a focus drug's cachexia-inducing properties. While DOX is widely used anticancer drug, it associated significant side effects, including cardiotoxicity and cachexia, which occur through mechanisms such as reduced insulin sensitivity, impaired glucose uptake, decreased adipogenesis. In this study, 12-week-old male Wistar albino rats were divided into four groups: Control (C), low-dose (DOX-L, 3...

10.69990/repvas.2025.2.1.5 article EN Research and practice in veterinary and animal science. 2024-12-04

This study aimed to diagnose Sarcina ventriculi in lambs with haemorrhagic abomasitis using histopathological and real-time PCR methods. The material used this consisted of 43 abomasum tissues recovered from presenting bleeding, ulcer, gas or a combination these the abomasum, that were brought for necropsy Department Pathology Veterinary Faculty, Selcuk University. samples stored 10% formaldehyde solution examinations Eppendorf tubes at −20 °C examinations. All analyzed by While S. pyruvate...

10.2754/avb202291030227 article EN Acta Veterinaria Brno 2022-01-01

Helicobacter species such as heilmannii, pylori, felis, bizzozeronii, salomonis have been identified in cats and dogs, research suggesting that these may be zoonotic agents increased recent years. The aim of this study is to reveal the presence H. heilmannii stomach liver tissues taken during necropsies domestic, stray shelter by real-time PCR histopathology compare histopathological findings results. material consisted from 41 who died different causes were necropsied. DNA was determined 36...

10.24880/maeuvfd.1218001 article EN Mehmet Akif Ersoy Üniversitesi Veteriner Fakültesi Dergisi 2023-08-29

Cisplatin (CP) is a platinum-based anticancer drug used to treat many different solid tumors. Although CP has strong properties, its clinical use limited due side effects such as ototoxicity, neurotoxicity, myelosuppression and nephrotoxicity. Taxifolin (Tax) reported exhibit various possess anti-inflammatory, antioxidant, antimicrobial, antiviral anticancer. In this study, we aimed investigate the possible of Tax on CP-induced This study consisted Control (C), (Tax), + (CP Tax) groups,...

10.35864/evmd.1458328 article EN Etlik Veteriner Mikrobiyoloji Dergisi 2024-05-22

In this study, it was aimed to determine Bordetella bronchiseptica, Mycoplasma felis, Staphylococcus aureus and Chlamydia which cause bronchopneumonia in cats, by Real-time PCR compare the pathological findings of identified agents. The material study constituted paraffin blocks belonging lungs, 21 were detected microscopic examination (with Hematoxylin Eosin (HE)) from a total 78 cats samples brought Selcuk University, Faculty Veterinary Medicine, Department Pathology for diagnosis....

10.53518/mjavl.1455252 article EN Manas Journal of Agriculture Veterinary and Life Sciences 2024-06-28

<title>Abstract</title> Background Transient Tachypnoea of the Newborn (TTN) is a common cause neonatal respiratory distress, often requiring support with Continuous Positive Airway Pressure (CPAP). This study compares effectiveness Bubble CPAP (BCPAP) and Ventilator-derived (VCPAP) in reducing NICU admissions late preterm term neonates TTN. Materials Methods retrospective cohort analysed 144 born at or beyond 34 weeks' gestation TTN who received either BCPAP (n = 70) VCPAP 74) delivery...

10.21203/rs.3.rs-5278451/v1 preprint EN 2024-10-25

Gentamicin (GM), which is in the aminoglycoside antibiotic class, frequently preferred today treatment of diseases caused by gram-negative bacteria. However, its significant side effects on liver and kidney functions limit clinical usefulness. The antioxidant anti-inflammatory medical activities eucalyptol (EUC, 1.8-cineole) have been reported different studies. This study aimed to evaluate EUC GM-induced hepatotoxicity. groups are consisted control (C), EUC, GM + there were 7 rats each...

10.35864/evmd.1549327 article EN Etlik Veteriner Mikrobiyoloji Dergisi 2024-12-02

Coligranulomatosis, which induces hepatic granulomas, and Marek's disease, one of the important neoplastic diseases in poultry, rarely causes outbreaks turkeys. In this study, etiological diagnoses were performed light post-mortem, histopathological, microbiological, immunohistochemistry studies turkeys that died a commercial establishment region Konya. post-mortem examination, many grey-white foci with diameter 3-10 mm, sometimes spread from serosa to parenchyma, found liver. Mucous exudate...

10.34233/jpr.744360 article EN cc-by-nc Tavukçuluk Araştırma Dergisi 2020-12-30

Urothelial carcinomas are malignant tumours originating from the epithelial layer of urinary bladder. In this instance, a case papillary and infiltrative urothelial carcinoma in bladder 2-year-old terrier dog was defined clinically, histopathologically immunohistochemically. The material presented consisted tissue samples that were surgically extirpated two-year-old terrier-breed female applied to Department Surgery Faculty Veterinary Medicine, Selcuk University with complaint hematuria....

10.31797/vetbio.1237692 article EN Journal of Advances in VetBio Science and Techniques 2023-04-28

There are many bacterial factors that cause respiratory diseases in dogs. Bacterial bronchopneumonia is a lung disease caused by bacteria the lower tract and parenchyma. In this study, it was aimed to determine Mycoplasma spp., Streptococcus Bordetella bronchiseptica, Klebsiella dogs with Real-time PCR compare histopathological findings determined according agents. The material of study consisted paraffin blocks 37 died due different reasons were found have microscopic examination....

10.35864/evmd.1354193 article EN Etlik Veteriner Mikrobiyoloji Dergisi 2023-10-30

Infectious bursal disease (IBD) is a viral that causes significant economic losses in young chickens, characterized by lymphoid depletion and inflammation the bursa Fabricius (BF). The incidence of shows an increasing trend all over world. Active passive immunization very important as well strict hygiene measures combating outbreaks. However, fact live-attenuated vaccines (mild, intermediate, hot) used for this purpose cause immunosuppression because damage seen limitation. In study, it was...

10.31797/vetbio.1069954 article EN Journal of Advances in VetBio Science and Techniques 2022-08-27

Bakır zehirlenmesi, bakırın vücuda alınımı ve atılımı arasındaki dengesizlikten kaynaklanan patolojik bir durumdur. Akut zehirlenme genellikle antihelmintik ilaçlar, mineral karışımları veya aşırı miktarda çözünür bakır tuzlarının uygulanmasından sonra görülür. Sunulan bu çalışmanın materyalini 900 toklu oluşturmaktadır. Hasta hayvanlarda abdominal sancı, ishal, hemoglobinüri, ikterus ölüm bulunmaktaydı. Yapılan nekropsiler sonucu deri altı yağ dokusu, serozalar organların etrafındaki dokuda...

10.35864/evmd.1187281 article TR Etlik Veteriner Mikrobiyoloji Dergisi 2022-11-24

In this study, a case of plasmacytoma with widespread metastasis in nine-year-old male Rottweiler dog was described by histopathological and immunohistochemical methods. Macroscopic examination revealed multifocal white or pink-red colored masses ranging size from 0,5 to 3 cm the lung, liver, mediastinal mesenterial lymph nodes, spleen, heart, pancreas, intestine kidneys. microscopic examination, tumor foci consisting mostly atypical plasma cells were observed mesenteric intestine,...

10.15312/eurasianjvetsci.2023.417 article EN Eurasian journal of veterinary sciences 2023-12-08

In humans and animals, botulism is a disease characterized by generalized progressive paralysis caused Clostridium botulinum neurotoxins (BoNT).BoNTs, defined in seven diff erent antigenic types (A to G), proteolyze SNAREs (synaptosomal-associated protein/SNAP-25 synaptobrevin) responsible for acetylcholine release peripheral cholinergic neurons, thus cause fl accid death.Currently, mouse experiments are considered the reference method definitive diagnosis.However, new diagnostic methods...

10.9775/kvfd.2020.25060 article EN Kafkas Universitesi Veteriner Fakultesi Dergisi 2021-01-01

A 4-year-old, 3.5-kg, entire male cat was presented with severe lethargy and increasing dyspnoea respiratory distress, nasal discharge, excessive salivation, loss of appetite weight loss, over the past few days. He an indoor-outdoor fed a homemade diet.&#x0D; On physical examination, laboured abdominal breathing, discharge salivation were evident. Mucous membranes slightly hyperaemic, no jaundice or cyanosis observed. There jugular distension. Gingival capillary refill time 2 seconds. Body...

10.46784/eavm.v14i1.268 article EN cc-by Archives of Veterinary Medicine 2021-09-01
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