A5039428378- Cancer, Hypoxia, and Metabolism
- Amino Acid Enzymes and Metabolism
- Cancer Research and Treatments
- Asthma and respiratory diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Epigenetics and DNA Methylation
- Cancer-related Molecular Pathways
- Respiratory Support and Mechanisms
Instituto de Investigación Biomédica de Málaga
2020-2021
Universidad de Málaga
2020-2021
Instituto de Parasitología y Biomedicina "López - Neyra"
2021
Glutaminase (GA) catalyzes the first step in mitochondrial glutaminolysis playing a key role cancer metabolic reprogramming. Humans express two types of GA isoforms: GLS and GLS2. isozymes have been consistently related to cell proliferation, but GLS2 remains poorly understood. is repressed many tumor cells better understanding its function tumorigenesis may further development new therapeutic approaches. We analyzed expression HCC, GBM neuroblastoma cells, as well monkey COS-7 cells....
Background and Purpose Acute lung injury (ALI), acute respiratory distress syndrome (ARDS) pulmonary fibrosis remain major causes of morbidity, mortality a healthcare burden in critically ill patient. There is an urgent need to identify factors causing susceptibility for the design new therapeutic agents. Here, we evaluate effectiveness immunomodulatory neuropeptide cortistatin regulate inflammation vivo . Experimental Approach ALI/ARDS were induced experimentally wild‐type...
An amendment to this paper has been published and can be accessed via a link at the top of paper.