Kanae Obukuro

ORCID: 0000-0002-9672-2344
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About
Contact & Profiles
Research Areas
  • Sleep and Wakefulness Research
  • Regulation of Appetite and Obesity
  • Sleep and related disorders
  • Biochemical Analysis and Sensing Techniques

Kumamoto University
2010-2014

We addressed the role of nitric oxide (NO) in orexin neuron degeneration that has been observed under various pathological conditions. Administration an NO donor NOC18 (50 nmol) into third ventricle mice resulted a significant decrease orexin-immunoreactive (-IR) neurons, contrast to modest change melanin-concentrating hormone-IR neurons. In addition, promoted formation orexin-A-IR aggregates within An endoplasmic reticulum stress inducer tunicamycin replicated effect with regard orexin-IR...

10.1523/jneurosci.0595-13.2013 article EN Journal of Neuroscience 2013-07-31
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