Yanyan Chen

ORCID: 0000-0002-9681-6105
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About
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Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Cardiovascular Function and Risk Factors
  • Gene expression and cancer classification
  • Retinal Imaging and Analysis
  • Blood Pressure and Hypertension Studies
  • Effects and risks of endocrine disrupting chemicals
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Bioinformatics and Genomic Networks
  • Environmental Toxicology and Ecotoxicology
  • Diabetes Management and Research
  • Cardiovascular Health and Disease Prevention

Huainan Normal University
2024

Xijing Hospital
2023

Air Force Medical University
2023

Hefei National Center for Physical Sciences at Nanoscale
2019

University of Science and Technology of China
2019

We aimed to examine the association between glycated hemoglobin (HbA1c), microvascular complications, and subclinical left ventricular (LV) systolic dysfunction, determine strength of correlation in asymptomatic patients with type 2 diabetes mellitus (T2DM).Global longitudinal strain (GLS) was employed assess LV function 152 enrolled T2DM preserved ejection fraction, cutoff for dysfunction predefined as GLS < 18%.According univariate analysis, reduced exhibited clinical features including...

10.1111/1753-0407.13369 article EN cc-by Journal of Diabetes 2023-02-22

The purpose of this research was to assess the relationship between severity diabetic retinopathy (DR) and indexes left ventricle (LV) structure function in type 2 diabetes mellitus (T2DM). Retrospective analysis 790 patients with T2DM preserved LV ejection fraction. Retinopathy stages were classified as no DR, early nonproliferative moderate severe or proliferative DR. electrocardiogram used myocardial conduction function. Echocardiography evaluate Patients divided into three groups based...

10.1155/2023/6588932 article EN cc-by Journal of Diabetes Research 2023-06-07

The broad-spectrum fungicides mepanipyrim (Mep) and cyprodinil (Cyp) have been reported to be used worldwide control gray mold of fruit crops. Consequently, they are often detected in the water food items. However, impacts potential mechanisms these two pesticides on environmental organisms remain unclear. Utilizing Caenorhabditis elegans (C. elegans) as model, toxic effects were analyzed after Mep Cyp exposure over four generations (P

10.1016/j.ecoenv.2024.117265 article EN cc-by-nc Ecotoxicology and Environmental Safety 2024-11-01

ABSTRACT Despite many genes associated with human diseases have been identified, disease mechanisms often remain elusive due to the lack of understanding how are connected functionally at pathways level. Within biological networks, likely map modules whose identification facilitates etiology studies but remains challenging. We describe a systematic approach identify disease-associated gene modules. A co-expression network based on graphical Gaussian model (GGM) was constructed using GTEx...

10.1101/598151 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-04-09
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