A5012995106- GaN-based semiconductor devices and materials
- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Health Systems, Economic Evaluations, Quality of Life
- Stroke Rehabilitation and Recovery
- Eating Disorders and Behaviors
- Cardiac Health and Mental Health
- Neurogenetic and Muscular Disorders Research
- Ga2O3 and related materials
- Respiratory viral infections research
- Amyotrophic Lateral Sclerosis Research
- ZnO doping and properties
- Metal and Thin Film Mechanics
- Asthma and respiratory diseases
- Semiconductor Quantum Structures and Devices
- Allergic Rhinitis and Sensitization
- Hair Growth and Disorders
- Silicon Carbide Semiconductor Technologies
- Photocathodes and Microchannel Plates
- Adolescent and Pediatric Healthcare
- Heart Rate Variability and Autonomic Control
- Restless Legs Syndrome Research
- Sleep and related disorders
Cleveland Clinic
2025
Jesse Brown VA Medical Center
2025
Carl Zeiss (United States)
2025
The University of Adelaide
2024
Women's and Children's Hospital
2024
RTI Health Solutions
2015-2023
ICF International (United States)
2022
Triangle
2019-2021
Williams (United States)
2018
Research Network (United States)
2016
Moderate‐to‐severe atopic dermatitis (AD) is a chronic disease characterized by intense, persistent and debilitating itch, resulting in sleep deprivation, signs of anxiety depression, impaired quality life reduced productivity. The Peak Pruritus Numerical Rating Scale (NRS) was developed validated as single‐item, patient‐reported outcome (PRO) itch severity. To describe the content validity psychometric assessment (test–retest reliability, construct validity, known‐groups sensitivity to...
Methemoglobinemia typically presents as functional anemia and hypoxemia. It is often recognized by a discordance between the pulse oximeter reading oxygen saturation measured on arterial blood gas. can be inherited or acquired, with some commonly-used medications causative agents. In patients hemolytic such in glucose-6-phosphate dehydrogenase deficiency, hemolysis may main clinical presentation, acquired methemoglobinemia after exposure to oxidizing We present case report of setting...
We report the performance of GaN p-i-n ultraviolet avalanche photodiodes grown on bulk substrates by metal-organic chemical vapor deposition. The low dislocation density in devices enables reverse-bias dark currents prior to breakdown for ∼30μm diameter mesa photodetectors. photoresponse is relatively independent bias voltage onset gain which occurs at an electric field ∼2.8MV∕cm. magnitude shows a positive temperature coefficient ∼0.05V∕K, confirming that mechanism dominates. With...
The temperature-dependent electrical characteristics of Schottky rectifiers fabricated with a SiO2 field plate on freestanding n− gallium nitride (GaN) substrate were reported in the temperature range 298–473K. barrier heights evaluated from forward current-voltage measurement revealed an increase height and series resistance but decrease ideality factor (n) increasing temperature. However, capacitance-voltage remained almost same throughout measured. Richardson constant extrapolated...
Thick GaN bars with [112̱0] orientation have been sliced from boules grown on freestanding films by hydride vapor phase epitaxy (HVPE) in the [0001] direction. High-resolution x-ray diffraction and transmission electron microscopy used to study structural quality defect distribution material comparison heteroepitaxially thick HVPE-GaN direction (11̱02)-plane sapphire. It is demonstrated that while heteroepitaxial possesses a high density of stacking faults partial dislocations, leading...
The Impact of Weight on Quality Life‐Lite (IWQOL‐Lite) is widely used in evaluations weight‐loss interventions, including pharmaceutical trials. Because this measure was developed using input from individuals undergoing intensive residential treatment, the IWQOL‐Lite may include concepts not relevant to clinical trial populations and be missing that are these populations. An alternative version, Clinical Trials Version (IWQOL‐Lite‐CT), validated according US Food Drug Administration's...
Background: Care transitions from hospital to skilled home health care (HH) often pose safety risks, especially for older adults. The Coming Home Intervention (CHI) was developed enhance these based on the Hospital-to-Home Health Transition Quality (H3TQ) index, a previously validated survey instrument assessing quality issues during hospital-to-HH transitions. Objectives: This study aimed pilot CHI and evaluate its impact at 2 large HH agencies in Baltimore, MD, New York, NY. Methods:...
Purpose This paper aims to give a unique, experiential patient perspective on Cassel Hospital’s outpatient treatment, Outreach; the authors were patients at time of writing paper. Design/methodology/approach A collaborative–autoethnographic approach immerses readers into psychodynamic, psychosocial community-based treatment. Initially, this discusses lived-experience research and therapeutic community including description Outreach programme its rationale. The second part provides subjective...
Pain is one of the most important domains affecting health-related quality life (HRQoL) in patients with psoriatic arthritis (PsA). Secukinumab has demonstrated rapid and sustained improvements signs symptoms, including HRQoL, among active PsA. This analysis evaluates effect secukinumab on patient-reported pain PsA through 104 weeks treatment. was assessed week using clinically relevant measures, change from baseline a visual analog scale (VAS) Short Form-36 (SF-36) bodily domain scores;...
A vertical Schottky diode rectifier was fabricated using a bulk n−GaN wafer. Pt contacts were prepared on the Ga face and full backside ohmic contact N by Ti∕Al. The root mean square surface roughnesses of faces are 0.61 4.7nm, respectively. relatively high breakdown field 5.46kV∕cm achieved with no additional edge termination. decreases as size device increases. background electron concentration GaN wafer low (5×1015cm−3), which may lead to even special forward turn-on voltage 2.4V at...
The authors have studied the effects of Fe doping at interface between GaN epitaxial layers for heterostructure field-effect transistors grown by metal-organic chemical vapor deposition and corresponding impact on device characteristics. structures were with different Fe-doped layer-template interface. Analysis measured electron charge distributions in heterostructures demonstrated important role regrowth No was observed transistor a thick layer. Characterization electrical properties...
Individuals with alopecia areata (AA) may experience significant impacts on their health-related quality of life. The novel Alopecia Areata Patient Priority Outcomes (AAPPO) questionnaire has been developed to assess hair loss signs, emotional symptoms, and activity limitations associated AA. objective this study was evaluate psychometric properties establish scoring the AAPPO in adults adolescents AA.Scoring measurement were examined using baseline 2-week follow-up data from a prospective,...
Psoriasis can greatly impact patients' lives by influencing clothing worn as well impairing sexual functioning. Secukinumab, a human monoclonal antibody selectively neutralizing interleukin-17A, has demonstrated good efficacy and safety in the treatment of moderate-to-severe psoriasis psoriatic arthritis with rapid onset action sustained response.This analysis using CLEAR study, phase 3b double-blind study comparing secukinumab vs. ustekinumab adults plaque psoriasis, evaluated effects on...
Abstract Background The Respiratory Infection Intensity and Impact Questionnaire (RiiQ™) is a patient-reported outcome measure designed to assess symptoms impacts of respiratory syncytial virus (RSV) infection. This study evaluated the construct validity, reliability, responsiveness RiiQ™ Systemic Symptoms Scale scores. Methods Prospective data were analyzed from total 1795 participants, including non-hospitalized patients with acute infection (ARI) no coinfections enrolled in Phase 2b RSV...
The authors present the fabrication and characterization of vertical-geometry Schottky-type ultraviolet (UV) photodetectors based on a bulk n-GaN substrate. By using low temperature rapid thermal annealing semitransparent Schottky contacts (nickel with 7% vanadium), they obtained an ultralow dark current 0.56pA at −10V reverse bias. A responsivity ∼0.09A∕W zero bias was measured for wavelength shorter than absorption edge GaN, it found to be independent incident power in range...
Background: Psoriasis can greatly impact patients' lives, influencing what clothing they wear and impairing their sexual functioning.Objective: To provide a detailed comparison of the secukinumab vs. etanercept on enabling patients with psoriasis to have more normal lives respect daily activities (DA) (e.g. choosing clothing) personal relationships (PR) functioning).Methods: Baseline Week 52 ERASURE FIXTURE data for 300 mg were analyzed. Treatment differences in mean scores DA PR subscales...
To investigate the longer-term effects of secukinumab 150 mg on fatigue in patients with ankylosing spondylitis (AS) MEASURE 1 study (up to 3 years) and 2 years).Patients active AS were randomized or placebo (10 mg/kg intravenous [IV] followed by subcutaneous) (150 subcutaneous). Patients naive treatment anti-tumor necrosis factor (anti-TNF-naive) therapy had an inadequate response/intolerance anti-TNF (anti-TNF-IR). Fatigue was measured using Functional Assessment Chronic Illness...
The Impact of Weight on Quality Life-Lite Clinical Trials Version (IWQOL-Lite-CT) was developed to assess weight-related physical and psychosocial functioning in the context clinical trials. Data from two pivotal trials once-weekly subcutaneous semaglutide for purpose weight management (NCT03548935 NCT03552757) were analysed confirm structure, reliability, validity, responsiveness IWQOL-Lite-CT evaluate magnitude meaningful within-patient change patients with overweight or obesity, without...
To assess self-reported physical functioning in patients with sporadic inclusion body myositis (sIBM), the sIBM Physical Functioning Assessment (sIFA) was developed. This research establishes validity, reliability, and responsiveness of sIFA sIBM.Data from 3 small, noninterventional, observational studies were analyzed. Several measures function included to validity. Reliability (Cronbach alpha, test-retest intraclass correlations), construct validity (correlations, analyses variance),...