A5076452647- Burn Injury Management and Outcomes
- Wound Healing and Treatments
- Injury Epidemiology and Prevention
- Disaster Response and Management
- Thermal Regulation in Medicine
- Cardiac Arrest and Resuscitation
- Dermatologic Treatments and Research
- Tissue Engineering and Regenerative Medicine
- Trauma and Emergency Care Studies
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Pressure Ulcer Prevention and Management
- Reconstructive Surgery and Microvascular Techniques
- Skin Protection and Aging
- Silk-based biomaterials and applications
- Electrospun Nanofibers in Biomedical Applications
- Mesenchymal stem cell research
- Urticaria and Related Conditions
- Drug-Induced Adverse Reactions
- Surgical Sutures and Adhesives
- Restraint-Related Deaths
- Nail Diseases and Treatments
- Corneal Surgery and Treatments
- Biomedical Ethics and Regulation
- Microwave Imaging and Scattering Analysis
Uppsala University Hospital
2016-2025
Uppsala University
2016-2025
Karlstad University
2016
Linköping University
2006-2013
Linköping University Hospital
2001-2010
Faculty of Public Health
2008
Plastic Surgery Hospital
2002
Impaired wound closure is a growing medical problem associated with metabolic diseases and aging. Immune cells play important roles in healing by following instructions from the microenvironment. Here, we developed technology to bioengineer microenvironment enhance abilities of immune cells. This resulted strongly accelerated was achieved transforming Lactobacilli plasmid encoding CXCL12. CXCL12-delivering bacteria administrated topically wounds mice efficiently enhanced increasing...
Our primary aim was to investigate, using a commercial radiometer, the ultraviolet C (UVC) dose received in different areas burn ICU ward room after an automated UVC decontamination. The secondary validate disposable UVC-dose indicator with radiometer readings.Disposable indicators and electronic were positioned ten positions room. decontaminated Tru-D™-UVC device. Colour changes of readings noted compared. Experiment repeated 10 times.The radiation varied between 15.9mJ/cm2 1068mJ/cm2...
Glutamine is thought to have beneficial effects on the metabolic and stress response severe injury. Clinical trials involving patients with burns other critically ill shown conflicting results regarding benefits risks of glutamine supplementation.
To compare three International Classification of Diseases code abstraction strategies that have previously been reported to mirror severe sepsis by examining retrospective Swedish national data from 1987 2005 inclusive.Retrospective cohort study.Swedish hospital discharge database.All admissions during the period were extracted and these patients screened for using strategies, which adapted version Diseases. Two included both Diseases, Ninth Revision Tenth codes, whereas one codes...
Spider silk is an interesting biomaterial for medical applications. Recently, a method production of recombinant spider protein (4RepCT) that forms macroscopic fibres in physiological solution was developed. Herein, 4RepCT and MersilkTM (control) were implanted subcutaneously rats seven days, without any negative systemic or local reactions. The tissue response, characterised by infiltration macrophages multinucleated cells, similar with both fibres, while only the 4RepCT-fibres supported...
Residential fires represent the largest category of fatal in Sweden. The purpose this study was to describe epidemiology residential Sweden and identify clusters events.Data collected from a database that combines information on with data forensic examinations Swedish Cause Death-register. Mortality rates were calculated for different strata using population statistics rescue service turnout reports. Cluster analysis performed multiple correspondence agglomerative hierarchical...
Foetal wounds are unique in their ability to heal rapidly without forming scars. The amniotic fluid, rich nutrients, growth factors, and hyaluronic acid, surrounds the foetus is essential foetal wound healing. healing properties of may be result high concentrations acid. This study aimed verify that fluid induces re-epithelialisation human skin vitro whether this dependent on Standard deep dermal were produced skin. samples, with a central wound, incubated different culture media. Varying...
This study examined the characteristics, experiences, motivations, and preferences of healthy volunteers participating in Phase I clinical trials Sweden. A descriptive, cross-sectional survey was conducted among 135 who had participated at least one trial from 2021 to 2024. Volunteers considered personnel, financial compensation, regulatory review approval as highly important factors their decision participate. Willingness participate varied depending on with greater reluctance for involving...
Burns represents a serious clinical problem because the diagnosis and assessment are very complex. This paper proposes methodology that combines use of advanced medical imaging with predictive modeling for improvement burn injury assessment. The proposed framework makes Adaptive Complex Independent Components Analysis (ACICA) Reference Region (TBSA) methods in conjunction deep learning techniques precise estimation depth Total Body Surface Area analysis. It also allows burns high accuracy,...
The dielectric properties of skin tissues in relation to different degrees burn are a necessary prerequisite for designing non-invasive microwave sensing modalities. Due the difficulties obtaining human tissue samples, such databases largely unavailable. To bridge knowledge gap this field, we attempt create database various burn-degree samples and their statistical analysis work. This research is part European "Senseburn" project, which aims diagnostic tool that can measure severity depth...
Reconstruction of the female breast after cancer surgery is a demanding task where methods used today suffer from several disadvantages. In present study we have investigated possibility to use tissue engineering regenerate human autologous tissue. Human mammary epithelial cells and preadipocytes were derived biopsies healthy women undergoing reduction mammoplasty, two celltypes co-cultured with conventional cell culture as well in 3-D matrices. The shows that it possible harvest both single...
Correcting soft tissue defects by autologous fat grafting is a routine procedure in plastic surgery. Its efficacy and safety has been discussed extensively several techniques of lipoinjection have developed. However, one bound to overcorrect 30%-70% or need repeat the because resorption transplant. The reasons are that many transplanted cells already differentiated, also there no nutritional support inner cell layers when they as fragments. By culturing adipocytes can ensure only...
Burn injury can be a life-threatening and traumatic event. Despite considerable risk for psychological morbidity, few outcome measures have been evaluated. The aim of this study was to examine the psychometric properties Swedish version Impact Event Scale-Revised (IES-R) in patients 1 year after burn (N = 147). A principal component analysis performed, results supported three-factor structure IES-R. High internal consistency intelligible associations with concurrent symptoms known factors...
Accurate determination of burn size significantly impacts both immediate management and long-term outcome. In the era evidence-based medicine, variability in TBSA% assessment shown by traditional methods may prove unacceptable technology-aided systems become "accepted standard." The objective this study was to push scenario limit investigating accuracy consistency estimations using a computer-aided tool. Five Laymen (health care-burn naïve people) were trained on handling tool Burn Case 3D©...
<title>Abstract</title> This study introduces a novel methodology for burn analysis, leveraging dynamic contrast enhancement in RGB images. The proposed approach integrates three pivotal techniques: Adaptive Complex Independent Components Analysis (ACICA) automated color correction, Reference Region (RR) precise region identification, and sophisticated modeling pixel-level classification. Our system aims to accurately efficiently diagnose depth area, facilitating personalized treatment from...