A5003666744- Autism Spectrum Disorder Research
- Suicide and Self-Harm Studies
- Child and Adolescent Psychosocial and Emotional Development
- Genetics and Neurodevelopmental Disorders
- Family and Disability Support Research
- COVID-19 and Mental Health
- Child Nutrition and Feeding Issues
- Virology and Viral Diseases
- Mental Health Treatment and Access
- Genetic Associations and Epidemiology
- Adipose Tissue and Metabolism
- Child and Adolescent Health
- Genomic variations and chromosomal abnormalities
- Bipolar Disorder and Treatment
- Epigenetics and DNA Methylation
- Bullying, Victimization, and Aggression
- Digital Mental Health Interventions
- Cannabis and Cannabinoid Research
- Child Development and Digital Technology
- Obsessive-Compulsive Spectrum Disorders
- Infant Development and Preterm Care
- COVID-19 diagnosis using AI
- Attention Deficit Hyperactivity Disorder
- Health disparities and outcomes
- Homelessness and Social Issues
Saint Louis University
2024-2025
UCLouvain Saint-Louis Brussels
2024-2025
UNSW Sydney
2020-2025
Western Sydney University
2022-2025
Jiangnan University
2025
GenMont Biotech (Taiwan)
2024
Neuroscience Research Australia
2023-2024
Jiangsu Provincial Center for Disease Control and Prevention
2024
Sichuan University
2006-2024
Ingham Institute
2021-2023
Resistin may be associated with obesity and cardiovascular diseases. However, it is unknown whether resistin directly contributes to angiogenesis. In the present study, we evaluated effects of on angiogenic potential, including endothelial cell proliferation, migration, capillary-like tube formation.Human coronary artery cells (HCAECs) were treated resistin. Cell proliferation was by [3H]thymidine incorporation MTS assays. migration assessed a modified Boyden chamber assay. Capillary-like...
OBJECTIVE: To assess whether age at onset variation reflects underlying genetic heterogeneity in bipolar disorder, the authors examined clinical and familial characteristics of disorder subjects from families with multiple affected members. METHOD: A total 211 1,856 were ascertained through I probands. All assessed Diagnostic Interview for Genetic Studies assigned diagnoses by trained clinicians using best estimate procedures. Admixture analysis probands was used to decompose age-at-onset...
Perfluoroalkyl substances (PFASs) are widespread, bioaccumulating, and persistent show placental transfer. Emerging research indicates associations between prenatal exposure low birth weight. The aim of this study was to assess the first trimester PFASs weight (BW) in Swedish Environmental, Longitudinal, Mother child, Asthma allergy (SELMA) examine whether differ girls boys.Eight were analyzed maternal serum (median: 10 weeks pregnancy). Associations PFAS outcomes with BW, BW for gestational...
Past studies have suggested that conditions experienced by women during pregnancy (e.g. obesity and gestational diabetes mellitus (GDM)) may be associated with having a child autism spectrum disorder (ASD). Our objective was to compare mothers who had diagnosed ASD of children non‐ASD developmental (DD) or without any reported DD (controls). To accomplish the we collected medical record data from patients resided in Cincinnati Children's Hospital Medical Center's (CCHMC) primary catchment...
Introduction: For COVID-19 patients accurate prediction of disease severity and mortality risk would greatly improve care delivery resource allocation. There are many patient-related factors, such as pre-existing comorbidities that affect severity. Since rapid automated profiling peripheral blood samples is widely available, we investigated how data from the might be used to predict clinical outcomes. Methods: We thus datasets with known outcomes by combining statistical comparison...
OBJECTIVES To analyze Australian national data to examine the impact of coronavirus disease 2019 (COVID-19) pandemic on mental health-related hospital presentations among children and adolescents during period with restrictions, after restrictions eased. METHODS We analyzed monthly inpatient admissions emergency department (ED) attendances from 6 large pediatric hospitals across Australia, using Bayesian structural time series models. The COVID-19 restriction was March 2020 December 2021...
Pulse wave velocity (PWV), a noninvasive index of central arterial stiffness, is potent predictor cardiovascular mortality and morbidity. Heritability linkage studies have pointed toward genetic component affecting PWV. We conducted genome-wide association study to identify single-nucleotide polymorphisms (SNPs) associated with PWV.The cohort included participants from the SardiNIA for whom PWV measures were available. Genotyping was performed in 4221 individuals, using either Affymetrix...
This study aimed to use machine learning (ML) models predict the risk of self-harm and suicide attempts in adolescents. We conducted secondary analysis cross-sectional data from Longitudinal Study Australian Children dataset. Several key variables at age 14-15 years were used or attempt 16-17 years. Random forest classification select optimal subset predictors subsequently make predictions. Among 2809 participants, 296 (10.54%) reported an act 145 (5.16%) attempting least once past 12...
Little is known regarding the time trend of mass shootings and associated risk factors. In current study, we intended to explore relevant factors for in U.S. We attempted identify with incidence rates at population level. evaluated if state-level gun ownership rate, serious mental illness poverty percentage, law permissiveness could predict shooting using Bayesian zero-inflated Poisson regression model. also tested nationwide rate increased over past three decades non-homogenous further...
Abstract Bisphenol A (BPA) exposure has been linked to neurodevelopmental disorders and effects on epigenetic regulation, such as DNA methylation, at genes involved in brain function. High doses of BPA have shown change expression regulation one gene, Grin2b , mice. Yet, if changes occur relevant animals humans not addressed. We investigated low-dose developmental affects methylation brains adult rats. Furthermore, we assessed associations between prenatal 7-year old children. found that...
Abstract DNA methylation (DNAm) profiles in central airway epithelial cells (AECs) may play a key role pathological processes asthma. The goal of the current study is to compare diagnostic performance DNAm markers across three tissues: AECs, nasal (NECs), and peripheral blood mononuclear (PBMCs). Additionally, we focused on results using machine learning algorithm context multi-locus effects evaluate optimal subset CpG sites. We obtained 74 subjects with asthma 41 controls from 15 14 NECs,...
Abstract Psychiatric symptoms are seen in some COVID-19 patients, as direct or indirect sequelae, but it is unclear whether SARS-CoV-2 infection interacts with underlying neuronal psychiatric susceptibilities. Such interactions might arise from immune responses, of neurons themselves may reflect social-psychological causes. To clarify this we sought the key gene expression pathways altered also affected bipolar disorder, post-traumatic stress disorder (PTSD) and schizophrenia, since identify...
Objective: This study aimed to investigate the help-seeking behaviours among children and young people (CYP) from culturally linguistically diverse (CALD) backgrounds for mental health (MH) needs in a multicultural Australian population. Methods: We analysed electronic medical records (eMR) of 8135 MH-related emergency department (ED) encounters CYP aged up 18 years across six public hospitals South Western Sydney Local Health District, Australia, January 2016 April 2022. Urgency MH care was...
<title>Abstract</title> Emerging evidence suggests gender-based heterogeneity in suicide risk associated with cannabis use, while the role of gender-dependent is elusive. The objective present study to determine whether use contributes differently pathway from depression or pain conditions non-fatal suicidal behaviors (e.g., ideation, plans, attempts) men versus women. We analyzed data was extracted National Survey Drug Use and Health (NSDUH) 2020–2022 during COVID-19 pandemic. Causal...