A5021362298- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Genetic Mapping and Diversity in Plants and Animals
- Fish Ecology and Management Studies
- Evolution and Genetic Dynamics
- Animal Behavior and Reproduction
- Animal Diversity and Health Studies
- Pharmacological Effects of Medicinal Plants
- Aquaculture disease management and microbiota
- Marine and fisheries research
- Metabolomics and Mass Spectrometry Studies
- Fish Biology and Ecology Studies
- Genomics and Phylogenetic Studies
- Livestock and Poultry Management
- Genetic Associations and Epidemiology
- Chromosomal and Genetic Variations
- Plant Pathogenic Bacteria Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Identification and Quantification in Food
- Biochemical Analysis and Sensing Techniques
University of Edinburgh
2014-2021
Institut de Biologia Evolutiva
2019
Norwegian University of Science and Technology
2011-2015
Significance Inbreeding depression is the decrease in fitness with increased genome-wide homozygosity that occurs offspring of related parents. Estimation its effect wild populations has been challenging, and while evidence inbreeding juvenile traits widespread, examples during later life stages remain rare. Here, a species extended maternal care, genomic coefficients, but not pedigree-based ones, revealed annual breeding success both sexes, rearing females. This contributed to estimates...
Data on hundreds or thousands of single nucleotide polymorphisms (SNPs) provide detailed information about the relationships between individuals, but currently few tools can turn this into a multigenerational pedigree. I present r package sequoia, which assigns parents, clusters half-siblings sharing an unsampled parent and grandparents to half-sibships. Assignments are made after consideration likelihoods all possible first-, second- third-degree focal as well traditional alternative being...
Abstract High-density linkage maps are an important tool to gain insight into the genetic architecture of traits evolutionary and economic interest, provide a resource characterize variation in recombination landscapes. Here, we used information from cattle genome 50 K Cervine Illumina BeadChip inform refine high-density map wild population red deer (Cervus elaphus). We constructed predicted 38,038 SNPs skeleton 10,835 across 34 groups. identified several chromosomal rearrangements lineage...
Abstract Recombination is a fundamental feature of sexual reproduction, ensuring proper disjunction, preventing mutation accumulation and generating new allelic combinations upon which selection can act. However it also mutagenic, breaks up favorable previously built by selection. Identifying the genetic drivers recombination rate variation key step in understanding causes consequences this variation, how loci associated with are evolving they affect potential population to respond However,...
Abstract Hybridization is a natural process at species range boundaries, but increasing numbers of are hybridizing due to direct or indirect human activities. In such cases anthropogenic hybridization, subsequent introgression can threaten the survival native species. To date, many systems have been studied with too few genetic markers assess level threat resulting from advanced backcrossing. Here, we use 44,999 single nucleotide polymorphisms (SNPs) and ADMIXTURE program study two areas...
The balance between stabilizing selection and migration of maladapted individuals has formerly been modeled using a variety quantitative genetic models increasing complexity, including based on constant expressed variance normality. infinitesimal model can accommodate nonnormality nonconstant as result linkage disequilibrium. It be seen parsimonious one-parameter that approximates the underlying details well when large number loci are involved. Here, performance this is compared to several...
At present, many ungulate populations have a complex history of isolation and translocation. Consequently, may experienced substantial reductions the level overall gene flow, yet simultaneously augmented levels long-distance flow. To investigate effect this dual anthropogenic impact on genetic landscape ungulates, we genotyped 35K SNPs in 47 red deer (Cervus elaphus) The Netherlands, including putative autochthonous relic as well allochthonous established private estates rewilding areas. We...
Interbreeding of two species in the wild implies introgression alleles from one into other only when admixed individuals survive and successfully backcross with parental species. Consequently, estimating proportion first generation hybrids a population may not inform about evolutionary impact hybridization. Samples obtained over long time span offer more accurate view spreading introgressed species' gene pool. Common quail (Coturnix coturnix) populations Europe have been restocked...
The study examined the density‐mediated effects on growth, survival and dispersal of wild farmed Atlantic salmon Salmo salar offspring in period immediately following emergence, using a substitutive design. In small confined stream channels, parr coexisting with had significantly poorer survival, than alone. Density did not affect this relationship. larger unconfined entered downstream trap higher numbers allopatry. results suggests that during earliest life stages, S. can outcompete ,...
Abstract Sexually selected traits show large variation and rapid evolution across the animal kingdom, yet genetic often persists within populations despite apparent directional selection. A key step in solving this long‐standing paradox is to determine architecture of sexually understand evolutionary drivers constraints at genomic level. Antlers are a form sexual weaponry male red deer ( Cervus elaphus ). On island Rum, Scotland, males with larger antlers have increased breeding success,...
Abstract Laboratory studies on associations between disease resistance and susceptibility major histocompatibility (MH) genes in Atlantic salmon Salmo salar have shown the importance of immunogenetics understanding capacity populations to fight specific diseases. However, occurrence virulence pathogens may vary spatially temporally wild, making it more complicated predict overall effect that MH exert fitness natural over several life‐history stages. Here we show variability is a significant...
Abstract Inbreeding depression is widely regarded as a driving force in the evolution of dispersal, mate choice and sperm selection. However, due to likely costs inbreeding avoidance, which are poorly understood, it unclear what extent selection avoid expected nature. Moreover, there currently very few empirical estimates strength against act (mating with relative), opposed fitness being inbred. Here, we use data from individual‐based study red deer on Scottish island Rum, strongly...
Abstract High density linkage maps are an important tool to gain insight into the genetic architecture of traits evolutionary and economic interest, provide a resource characterise variation in recombination landscapes. Here, we used information from cattle genome 50K Cervine Illumina BeadChip inform refine high map wild population red deer ( Cervus elaphus ). We constructed predicted 38,038 SNPs skeleton 10,835 across 34 groups. identified several chromosomal rearrangements lineage relative...
Abstract Recombination is a fundamental feature of sexual reproduction, ensuring proper disjunction, preventing mutation accumulation and generating new allelic combinations upon which selection can act. However it also mutagenic, breaks up favourable previously built by selection. Identifying the genetic drivers recombination rate variation key step in understanding causes consequences this variation, how lociassociated with are evolving they affect potential population to respond However,...
Abstract Hybridization is a natural process at species range boundaries, but increasing numbers of are hybridizing due to direct or indirect human activities. In such cases anthropogenic hybridization, subsequent introgression can threaten the survival native species. To date many systems have been studied with too few genetic markers assess level threat resulting from advanced backcrossing. Here we use 44,999 single nucleotide polymorphisms and ADMIXTURE program study two areas Scotland...