A5069574561- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Microbial Community Ecology and Physiology
- Gene expression and cancer classification
- Genomics and Phylogenetic Studies
- Protist diversity and phylogeny
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Environmental DNA in Biodiversity Studies
- Evolution and Genetic Dynamics
- Animal Behavior and Reproduction
- Biochemical Analysis and Sensing Techniques
- Regulation of Appetite and Obesity
- melanin and skin pigmentation
École Nationale Vétérinaire de Toulouse
2023-2024
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2022-2024
Université de Toulouse
2023-2024
Génétique Physiologie et Systèmes d'Elevage
2023-2024
University of Edinburgh
2017-2023
Edinburgh College
2023
Laboratoire de Génétique Cellulaire
2022
University of Glasgow
2016-2018
Bielefeld University
2016
The distribution of runs homozygosity (ROH) may be shaped by a number interacting processes such as selection, recombination and population history, but little is known about the importance these mechanisms in shaping ROH wild populations. We combined an empirical dataset >3000 red deer genotyped at >35,000 genome-wide autosomal SNPs evolutionary simulations to investigate influence each factors on ROH. assessed focal comparison effect history. investigated role using both physical map...
Environmental DNA (eDNA) metabarcoding is a relatively new monitoring tool featuring in an increasing number of applications such as the facilitation accurate and cost effective detection species environmental samples. eDNA likely to have major impact on ability salmonid aquaculture industry producers their regulators detect presence abundance pathogens other biological threats surrounding environment. However, for develop into useful bio-monitoring it necessary (a) validate that sequence...
Abstract Meiotic recombination through chromosomal crossing-over is a fundamental feature of sex and an important driver genomic diversity. It ensures proper disjunction, allows increased selection responses, prevents mutation accumulation; however, it also mutagenic can break up favourable haplotypes. This cost/benefit dynamic likely to vary depending on mechanistic evolutionary contexts, indeed, rates show huge variation in nature. Identifying the genetic architecture this key...
Abstract Meiotic recombination through chromosomal crossing-over is a fundamental feature of sex and an important driver genomic diversity. It ensures proper disjunction, allows increased selection responses, prevents mutation accumulation; however, it also mutagenic can break up favorable haplotypes. This cost–benefit dynamic likely to vary depending on mechanistic evolutionary contexts, indeed, rates show huge variation in nature. Identifying the genetic architecture this key understanding...
Underutilized sheep and goat breeds can adapt to challenging environments due their genetics. Integrating publicly available genomic datasets with new data will facilitate genetic diversity analyses; however, this process is complicated by discrepancies, such as outdated assembly versions or different formats. Here, we present the SMARTER-database, a collection of tools scripts standardize metadata, mainly from SNP chip arrays on global small ruminant populations, focus reproducibility....
Although the genetic basis of color variation has been extensively studied in humans and domestic animals, polymorphisms responsible for different morphs remain to be elucidated many wild vertebrate species. For example, hypopigmentation observed numerous marine mammal species but underlying mutations have not identified. A particularly compelling candidate gene explaining polymorphism is melanocortin 1 receptor (MC1R), which plays a key role regulation pigment production. We therefore used...
Abstract Sexually selected traits show large variation and rapid evolution across the animal kingdom, yet genetic often persists within populations despite apparent directional selection. A key step in solving this long‐standing paradox is to determine architecture of sexually understand evolutionary drivers constraints at genomic level. Antlers are a form sexual weaponry male red deer ( Cervus elaphus ). On island Rum, Scotland, males with larger antlers have increased breeding success,...
Abstract Sequencing of environmental DNA (eDNA-seq) is an emergent new monitoring tool that promises to facilitate the accurate and cost effective detection species in samples. eDNA likely have a major impact on ability salmonid aquaculture industry producers their regulators detect presence abundance pathogens other biological threats surrounding environment. However, for eDNA-seq develop into useful bio-monitoring it necessary (a) validate sequence datasets derived from amplification...
Underutilized sheep and goat breeds have the ability to adapt challenging environments due their genetic composition. Integrating publicly available genomic datasets with new data will facilitate diversity analyses; however, this process is complicated by important discrepancies, such as outdated assembly versions or different formats. Here we present SMARTER-database, a collection of tools scripts standardize metadata mainly from SNP chips arrays on global small ruminant populations focus...
Abstract The distribution of runs homozygosity (ROH) may be shaped by a number interacting processes such as selection, recombination and population history, but little is known about the importance these mechanisms in shaping ROH wild populations. We combined an empirical dataset >3,000 red deer genotyped at >35,000 genome-wide autosomal SNPs evolutionary simulations to investigate influence each factors on ROH. assessed location two populations (a focal comparison) effect history....
Males and females largely share the same genome, but optimal value of a trait can differ between sexes. If these traits genetic basis sexes, intra-locus sexual conflict prevent them from reaching their optima. Here, we explore sex-specific early life survival in wild red deer, species with extensive dimorphism, using genomic dataset >38,000 genotyped SNPs for 3,067 individuals. We conducted variance component analysis Bayesian mixed model approach. were ~14% more likely to die before age...
Abstract Sexually-selected traits show large variation and rapid evolution across the animal kingdom, yet genetic often persists within populations despite apparent directional selection. A key step in solving this long-standing paradox is to determine architecture of sexually-selected understand evolutionary drivers constraints at genomic level. Antlers are a form sexual weaponry male red deer. On island Rum, Scotland, males with larger antlers have increased breeding success, there has...